CompoundList
Sign in
Murcko scaffold

N-Benzyl-5-oxopyrrolidine-2-carboxamide scaffold

16 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
16
With full pages
4
Scaffold SMILES

O=C1CCC(C(=O)NCc2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Benzyl-5-oxopyrrolidine-2-carboxamide page
Murcko scaffold O=C1CCC(C(=O)NCc2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Pyroglutamylbenzylamide chemical structure, C12H14N2O2, CAS 87766-32-3
Pyroglutamylbenzylamide
CAS 87766-32-3C12H14N2O2
N-(4-Chlorobenzyl)-5-oxoprolinamide chemical structure, C12H13ClN2O2, CAS 100119-21-9
N-(4-Chlorobenzyl)-5-oxoprolinamide
CAS 100119-21-9C12H13ClN2O2
N-Benzyl-5-oxopyrrolidine-2-carboxamide chemical structure, C12H14N2O2, CAS 100135-07-7
N-Benzyl-5-oxopyrrolidine-2-carboxamide
CAS 100135-07-7C12H14N2O2
N-Benzyl-5-oxo-D-prolinamide chemical structure, C12H14N2O2, CAS 178327-71-4
N-Benzyl-5-oxo-D-prolinamide
CAS 178327-71-4C12H14N2O2
5-Oxo-N-[(1S)-1-phenylethyl]-L-prolinamide chemical structure, C13H16N2O2, CAS 261951-62-6
5-Oxo-N-[(1S)-1-phenylethyl]-L-prolinamide
CAS 261951-62-6C13H16N2O2
Gsk-1482160 chemical structure, C14H14ClF3N2O2, CAS 1001389-72-5
Gsk-1482160
CAS 1001389-72-5C14H14ClF3N2O2
N-(2-Bromobenzyl)-N-methyl-5-oxopyrrolidine-2-carboxamide chemical structure, C13H15BrN2O2, CAS 1252057-59-2
N-(2-Bromobenzyl)-N-methyl-5-oxopyrrolidine-2-carboxamide
CAS 1252057-59-2C13H15BrN2O2
N-[Cyano(3,4-dichlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide chemical structure, C13H11Cl2N3O2, CAS 1355461-24-3
N-[Cyano(3,4-dichlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide
CAS 1355461-24-3C13H11Cl2N3O2
N-(4-Bromobenzyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C12H13BrN2O2, CAS 1290929-52-0
N-(4-Bromobenzyl)-5-oxopyrrolidine-2-carboxamide
CAS 1290929-52-0C12H13BrN2O2
N-(3-Bromobenzyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C12H13BrN2O2, CAS 1290868-15-3
N-(3-Bromobenzyl)-5-oxopyrrolidine-2-carboxamide
CAS 1290868-15-3C12H13BrN2O2
(2R)-N-{[2-Chloro-3-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxopyrrolidine-2-carboxamide chemical structure, C14H14ClF3N2O2, CAS 1001390-06-2
(2R)-N-{[2-Chloro-3-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxopyrrolidine-2-carboxamide
CAS 1001390-06-2C14H14ClF3N2O2
Gsk1370319A chemical structure, C13H14Cl2N2O2, CAS 1001389-31-6
Gsk1370319A
CAS 1001389-31-6C13H14Cl2N2O2
N-(2-Chlorobenzyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C12H13ClN2O2, CAS 1786103-23-8
N-(2-Chlorobenzyl)-5-oxopyrrolidine-2-carboxamide
CAS 1786103-23-8C12H13ClN2O2
N-(3-Chloro-4-methoxybenzyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C13H15ClN2O3, CAS 1786238-17-2
N-(3-Chloro-4-methoxybenzyl)-5-oxopyrrolidine-2-carboxamide
CAS 1786238-17-2C13H15ClN2O3
N-(1-(3-Chlorophenyl)ethyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C13H15ClN2O2, CAS 1922698-11-0
N-(1-(3-Chlorophenyl)ethyl)-5-oxopyrrolidine-2-carboxamide
CAS 1922698-11-0C13H15ClN2O2
GSK-1482160 (isomer) chemical structure, C14H14ClF3N2O2, CAS 1695551-19-9
GSK-1482160 (isomer)
CAS 1695551-19-9C14H14ClF3N2O2