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Murcko scaffold

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-phenylacetamide scaffold

36 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 17
Chemicals: 36
With full pages: 9

Scaffold SMILES

O=C(CC1SC(=O)NC1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-phenylacetamide page

Murcko scaffold O=C(CC1SC(=O)NC1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-ethenylphenyl)acetamide chemical structure, C13H12N2O3S, CAS 75851-50-2

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-ethenylphenyl)acetamide

CAS 75851-50-2C₁₃H₁₂N₂O₃S

2-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-yl)-N-phenylacetamide chemical structure, C14H16N2O3S, CAS 499117-49-6

2-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-yl)-N-phenylacetamide

CAS 499117-49-6C₁₄H₁₆N₂O₃S

N-(4-Bromophenyl)-2-(2,4-dioxo-3-propyl-1,3-thiazolidin-5-yl)acetamide chemical structure, C14H15BrN2O3S, CAS 488733-36-4

N-(4-Bromophenyl)-2-(2,4-dioxo-3-propyl-1,3-thiazolidin-5-yl)acetamide

CAS 488733-36-4C₁₄H₁₅BrN₂O₃S

N-(4-Chlorophenyl)-2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C11H9ClN2O3S, CAS 58471-54-8

N-(4-Chlorophenyl)-2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamide

CAS 58471-54-8C₁₁H₉ClN₂O₃S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-hydroxyphenyl)acetamide chemical structure, C11H10N2O4S, CAS 58471-62-8

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-hydroxyphenyl)acetamide

CAS 58471-62-8C₁₁H₁₀N₂O₄S

Ethyl 4-[2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamido]benzoate chemical structure, C14H14N2O5S, CAS 308294-47-5

Ethyl 4-[2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamido]benzoate

CAS 308294-47-5C₁₄H₁₄N₂O₅S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-methylphenyl)acetamide chemical structure, C12H12N2O3S, CAS 314260-23-6

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-methylphenyl)acetamide

CAS 314260-23-6C₁₂H₁₂N₂O₃S

4-{[(2,4-Dioxo-1,3-thiazolidin-5-yl)acetyl]amino}benzoic acid chemical structure, C12H10N2O5S, CAS 58471-60-6

4-{[(2,4-Dioxo-1,3-thiazolidin-5-yl)acetyl]amino}benzoic acid

CAS 58471-60-6C₁₂H₁₀N₂O₅S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-phenylacetamide chemical structure, C11H10N2O3S, CAS 308292-67-3

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-phenylacetamide

CAS 308292-67-3C₁₁H₁₀N₂O₃S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-sulfamoylphenyl)acetamide chemical structure, C11H11N3O5S2, CAS 308295-15-0

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-sulfamoylphenyl)acetamide

CAS 308295-15-0C₁₁H₁₁N₃O₅S₂

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide chemical structure, C13H14N2O4S, CAS 425648-10-8

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide

CAS 425648-10-8C₁₃H₁₄N₂O₄S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-methoxyphenyl)acetamide chemical structure, C12H12N2O4S, CAS 58471-55-9

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-methoxyphenyl)acetamide

CAS 58471-55-9C₁₂H₁₂N₂O₄S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-nitrophenyl)acetamide chemical structure, C11H9N3O5S, CAS 58471-59-3

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-nitrophenyl)acetamide

CAS 58471-59-3C₁₁H₉N₃O₅S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(2-hydroxyphenyl)acetamide chemical structure, C11H10N2O4S, CAS 380212-08-8

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(2-hydroxyphenyl)acetamide

CAS 380212-08-8C₁₁H₁₀N₂O₄S

N-(5-Chloro-2-hydroxyphenyl)-2-(2-hydroxy-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide chemical structure, C11H9ClN2O4S, CAS 496020-68-9

N-(5-Chloro-2-hydroxyphenyl)-2-(2-hydroxy-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide

CAS 496020-68-9C₁₁H₉ClN₂O₄S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C12H9F3N2O3S, CAS 58471-61-7

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-[3-(trifluoromethyl)phenyl]acetamide

CAS 58471-61-7C₁₂H₉F₃N₂O₃S

2-(2,4-Dioxo-3-propyl-thiazolidin-5-yl)-N-p-tolyl-acetamide chemical structure, C15H18N2O3S, CAS 488803-87-8

2-(2,4-Dioxo-3-propyl-thiazolidin-5-yl)-N-p-tolyl-acetamide

CAS 488803-87-8C₁₅H₁₈N₂O₃S

2-(2,4-Dioxo-3-propyl-thiazolidin-5-yl)-N-o-tolyl-acetamide chemical structure, C15H18N2O3S, CAS 497082-34-5

2-(2,4-Dioxo-3-propyl-thiazolidin-5-yl)-N-o-tolyl-acetamide

CAS 497082-34-5C₁₅H₁₈N₂O₃S

2-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide chemical structure, C16H20N2O4S, CAS 488793-59-5

2-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide

CAS 488793-59-5C₁₆H₂₀N₂O₄S

Ethyl 4-{[(2,4-dioxo-3-propyl-1,3-thiazolidin-5-yl)acetyl]amino}benzoate chemical structure, C17H20N2O5S, CAS 497082-35-6

Ethyl 4-{[(2,4-dioxo-3-propyl-1,3-thiazolidin-5-yl)acetyl]amino}benzoate

CAS 497082-35-6C₁₇H₂₀N₂O₅S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(3-nitrophenyl)acetamide chemical structure, C11H9N3O5S, CAS 449185-79-9

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(3-nitrophenyl)acetamide

CAS 449185-79-9C₁₁H₉N₃O₅S

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(3-hydroxyphenyl)acetamide chemical structure, C11H10N2O4S, CAS 308294-46-4

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(3-hydroxyphenyl)acetamide

CAS 308294-46-4C₁₁H₁₀N₂O₄S

2-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-yl)-N-(4-iodophenyl)acetamide chemical structure, C14H15IN2O3S, CAS 489399-91-9

2-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-yl)-N-(4-iodophenyl)acetamide

CAS 489399-91-9C₁₄H₁₅IN₂O₃S

2-{[(2,4-Dioxo-1,3-thiazolidin-5-yl)acetyl]amino}-5-hydroxybenzoic acid chemical structure, C12H10N2O6S, CAS 902307-96-4

2-{[(2,4-Dioxo-1,3-thiazolidin-5-yl)acetyl]amino}-5-hydroxybenzoic acid

CAS 902307-96-4C₁₂H₁₀N₂O₆S