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Murcko scaffold

2-Azetidinone scaffold

485 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
485
With full pages
48
Scaffold SMILES

O=C1CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Azetidinone page
Murcko scaffold O=C1CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 337 to 384 of 485 chemicals

(3R)-3-(Trimethylsilyl)-2-azetidinone chemical structure, C6H13NOSi, CAS 1199589-84-8
(3R)-3-(Trimethylsilyl)-2-azetidinone
CAS 1199589-84-8C6H13NOSi
4-(2-Hydroxypropyl)azetidin-2-one chemical structure, C6H11NO2, CAS 79009-11-3
4-(2-Hydroxypropyl)azetidin-2-one
CAS 79009-11-3C6H11NO2
(3R,4S)-4-(Prop-1-en-1-yl)-3-{[tri(propan-2-yl)silyl]oxy}azetidin-2-one chemical structure, C15H29NO2Si, CAS 178250-08-3
(3R,4S)-4-(Prop-1-en-1-yl)-3-{[tri(propan-2-yl)silyl]oxy}azetidin-2-one
CAS 178250-08-3C15H29NO2Si
(3S-Cis)-3-t-butoxycarbonylamino-4-methylazetidinone chemical structure, C9H16N2O3, CAS 80542-81-0
(3S-Cis)-3-t-butoxycarbonylamino-4-methylazetidinone
CAS 80542-81-0C9H16N2O3
(3S-Cis)-3-t-butoxycarbonylamino-1-methoxy-4-methylazetidinone chemical structure, C10H18N2O4, CAS 80543-40-4
(3S-Cis)-3-t-butoxycarbonylamino-1-methoxy-4-methylazetidinone
CAS 80543-40-4C10H18N2O4
(3S,4S)-3-Azido-4-(trifluoromethyl)azetidin-2-one chemical structure, C4H3F3N4O, CAS 88968-83-6
(3S,4S)-3-Azido-4-(trifluoromethyl)azetidin-2-one
CAS 88968-83-6C4H3F3N4O
(2S,3R)-tert-Butyl 2-(2,2-difluorovinyl)-4-oxo-3-((triisopropylsilyl)oxy)azetidine-1-carboxylate chemical structure, C19H33F2NO4Si, CAS 926307-01-9
(2S,3R)-tert-Butyl 2-(2,2-difluorovinyl)-4-oxo-3-((triisopropylsilyl)oxy)azetidine-1-carboxylate
CAS 926307-01-9C19H33F2NO4Si
3-(Methylamino)azetidin-2-one chemical structure, C4H8N2O, CAS 2919946-27-1
3-(Methylamino)azetidin-2-one
CAS 2919946-27-1C4H8N2O
tert-Butyl 2-ethenyl-2-methyl-4-oxoazetidine-1-carboxylate chemical structure, C11H17NO3, CAS 1335042-72-2
tert-Butyl 2-ethenyl-2-methyl-4-oxoazetidine-1-carboxylate
CAS 1335042-72-2C11H17NO3
tert-Butyl 2-oxo-4-(propan-2-yl)azetidine-1-carboxylate chemical structure, C11H19NO3, CAS 1335042-42-6
tert-Butyl 2-oxo-4-(propan-2-yl)azetidine-1-carboxylate
CAS 1335042-42-6C11H19NO3
tert-Butyl 2-tert-butyl-4-oxoazetidine-1-carboxylate chemical structure, C12H21NO3, CAS 1335042-29-9
tert-Butyl 2-tert-butyl-4-oxoazetidine-1-carboxylate
CAS 1335042-29-9C12H21NO3
tert-Butyl 2-(2-methylpropyl)-4-oxoazetidine-1-carboxylate chemical structure, C12H21NO3, CAS 1335042-75-5
tert-Butyl 2-(2-methylpropyl)-4-oxoazetidine-1-carboxylate
CAS 1335042-75-5C12H21NO3
3,3-Dimethyl-2-oxo-1-azetidineacetic acid chemical structure, C7H11NO3, CAS 130132-67-1
3,3-Dimethyl-2-oxo-1-azetidineacetic acid
CAS 130132-67-1C7H11NO3
4-(1,1-Difluoroethyl)-3-hydroxy-azetidin-2-one chemical structure, C5H7F2NO2, CAS 1824387-82-7
4-(1,1-Difluoroethyl)-3-hydroxy-azetidin-2-one
CAS 1824387-82-7C5H7F2NO2
3-Amino-1-methylazetidin-2-one chemical structure, C4H8N2O, CAS 38504-97-1
3-Amino-1-methylazetidin-2-one
CAS 38504-97-1C4H8N2O
3-Amino-1-ethylazetidin-2-one chemical structure, C5H10N2O, CAS 1565561-50-3
3-Amino-1-ethylazetidin-2-one
CAS 1565561-50-3C5H10N2O
(3S)-3-Aminoazetidin-2-one hydrochloride chemical structure, C3H7ClN2O, CAS 2044711-48-8
(3S)-3-Aminoazetidin-2-one hydrochloride
CAS 2044711-48-8C3H7ClN2O
Isosulfazecin chemical structure, C12H20N4O9S, CAS 77900-75-5
Isosulfazecin
CAS 77900-75-5C12H20N4O9S
MM 42842 chemical structure, C13H22N4O9S, CAS 113784-28-4
MM 42842
CAS 113784-28-4C13H22N4O9S
Sulfazecin sodium chemical structure, C12H19N4NaO9S, CAS 80734-22-1
Sulfazecin sodium
CAS 80734-22-1C12H19N4NaO9S
3-Ethyl-4-(2-hydroxyethyl)-1-[tri(propan-2-yl)silyl]azetidin-2-one chemical structure, C16H33NO2Si, CAS 89242-02-4
3-Ethyl-4-(2-hydroxyethyl)-1-[tri(propan-2-yl)silyl]azetidin-2-one
CAS 89242-02-4C16H33NO2Si
2-Acetyl-2-chloro-4-oxoazetidine-3-carboxylic acid chemical structure, C6H6ClNO4, CAS 89403-83-8
2-Acetyl-2-chloro-4-oxoazetidine-3-carboxylic acid
CAS 89403-83-8C6H6ClNO4
Diethyl methyl(4-oxoazetidin-2-yl)propanedioate chemical structure, C11H17NO5, CAS 89691-20-3
Diethyl methyl(4-oxoazetidin-2-yl)propanedioate
CAS 89691-20-3C11H17NO5
4-{2-[(Trimethylsilyl)oxy]ethyl}azetidin-2-one chemical structure, C8H17NO2Si, CAS 91504-01-7
4-{2-[(Trimethylsilyl)oxy]ethyl}azetidin-2-one
CAS 91504-01-7C8H17NO2Si