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Murcko scaffold

2-Azetidinone scaffold

485 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
485
With full pages
48
Scaffold SMILES

O=C1CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Azetidinone page
Murcko scaffold O=C1CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 289 to 336 of 485 chemicals

(2S,3R)-3-(Dimethylamino)-4-oxoazetidine-2-carboxylic acid chemical structure, C6H10N2O3, CAS 765861-74-3
(2S,3R)-3-(Dimethylamino)-4-oxoazetidine-2-carboxylic acid
CAS 765861-74-3C6H10N2O3
(R)-1,3,3-Trimethyl-4-oxoazetidine-2-carbaldehyde chemical structure, C7H11NO2, CAS 227288-01-9
(R)-1,3,3-Trimethyl-4-oxoazetidine-2-carbaldehyde
CAS 227288-01-9C7H11NO2
1,1'-(1-Hydroxy-4-oxoazetidine-2,2-diyl)diethanone chemical structure, C7H9NO4, CAS 141942-33-8
1,1'-(1-Hydroxy-4-oxoazetidine-2,2-diyl)diethanone
CAS 141942-33-8C7H9NO4
1-Acetyl-3-isopropylazetidin-2-one chemical structure, C8H13NO2, CAS 111463-22-0
1-Acetyl-3-isopropylazetidin-2-one
CAS 111463-22-0C8H13NO2
2-Azetidinone, 3-acetyl-1-ethyl-4-methyl- chemical structure, C8H13NO2, CAS 76269-84-6
2-Azetidinone, 3-acetyl-1-ethyl-4-methyl-
CAS 76269-84-6C8H13NO2
1-(2-Methylprop-2-enyl)azetidin-2-one chemical structure, C7H11NO, CAS 172326-86-2
1-(2-Methylprop-2-enyl)azetidin-2-one
CAS 172326-86-2C7H11NO
2-Azetidinone, 1-(1-oxo-2-propenyl)- chemical structure, C6H7NO2, CAS 151586-60-6
2-Azetidinone, 1-(1-oxo-2-propenyl)-
CAS 151586-60-6C6H7NO2
1-Acetyl-4-fluoroazetidin-2-one chemical structure, C5H6FNO2, CAS 246181-66-8
1-Acetyl-4-fluoroazetidin-2-one
CAS 246181-66-8C5H6FNO2
2-Azetidinone, 1-(2-methyl-1-oxo-2-propenyl)- chemical structure, C7H9NO2, CAS 405114-51-4
2-Azetidinone, 1-(2-methyl-1-oxo-2-propenyl)-
CAS 405114-51-4C7H9NO2
2-(2-Methyl-4-oxoazetidin-1-yl)acetic acid chemical structure, C6H9NO3, CAS 748097-11-2
2-(2-Methyl-4-oxoazetidin-1-yl)acetic acid
CAS 748097-11-2C6H9NO3
(2-Oxoazetidin-1-yl)methyl acetate chemical structure, C6H9NO3, CAS 701910-98-7
(2-Oxoazetidin-1-yl)methyl acetate
CAS 701910-98-7C6H9NO3
2-(3-Hydroxy-2-oxoazetidin-1-yl)acetamide chemical structure, C5H8N2O3, CAS 522644-48-0
2-(3-Hydroxy-2-oxoazetidin-1-yl)acetamide
CAS 522644-48-0C5H8N2O3
1-(Dimethoxymethyl)azetidin-2-one chemical structure, C6H11NO3, CAS 312909-09-4
1-(Dimethoxymethyl)azetidin-2-one
CAS 312909-09-4C6H11NO3
2-Azetidinone, 4-ethenyl-4-methyl-1-(2-propenyl)- chemical structure, C9H13NO, CAS 701304-73-6
2-Azetidinone, 4-ethenyl-4-methyl-1-(2-propenyl)-
CAS 701304-73-6C9H13NO
2-Azetidinone, 1-(3-butenyl)-4-ethenyl-4-methyl- chemical structure, C10H15NO, CAS 701304-71-4
2-Azetidinone, 1-(3-butenyl)-4-ethenyl-4-methyl-
CAS 701304-71-4C10H15NO
(2R,3S)-3-Amino-4-oxo-1-sulfoazetidine-2-carboxylic acid chemical structure, C4H6N2O6S, CAS 167685-65-6
(2R,3S)-3-Amino-4-oxo-1-sulfoazetidine-2-carboxylic acid
CAS 167685-65-6C4H6N2O6S
2-[(2S,3S)-3-Amino-2-methyl-4-oxoazetidine-1-carbonyl]oxyacetic acid chemical structure, C7H10N2O5, CAS 98730-75-7
2-[(2S,3S)-3-Amino-2-methyl-4-oxoazetidine-1-carbonyl]oxyacetic acid
CAS 98730-75-7C7H10N2O5
Methyl (2S,3S)-3-methyl-4-oxoazetidine-2-carboxylate chemical structure, C6H9NO3, CAS 144452-34-6
Methyl (2S,3S)-3-methyl-4-oxoazetidine-2-carboxylate
CAS 144452-34-6C6H9NO3
(R)-Methyl 3,3-dimethyl-4-oxoazetidine-2-carboxylate chemical structure, C7H11NO3, CAS 228868-38-0
(R)-Methyl 3,3-dimethyl-4-oxoazetidine-2-carboxylate
CAS 228868-38-0C7H11NO3
(R)-Methyl 1-methoxy-4-oxoazetidine-2-carboxylate chemical structure, C6H9NO4, CAS 108550-47-6
(R)-Methyl 1-methoxy-4-oxoazetidine-2-carboxylate
CAS 108550-47-6C6H9NO4
(4R)-4-Bromoazetidin-2-one chemical structure, C3H4BrNO, CAS 594866-00-9
(4R)-4-Bromoazetidin-2-one
CAS 594866-00-9C3H4BrNO
4-Pent-4-enoxyazetidin-2-one chemical structure, C8H13NO2, CAS 216857-00-0
4-Pent-4-enoxyazetidin-2-one
CAS 216857-00-0C8H13NO2
3-Methoxy-4-(2-methylprop-1-en-1-yl)azetidin-2-one chemical structure, C8H13NO2, CAS 216366-75-5
3-Methoxy-4-(2-methylprop-1-en-1-yl)azetidin-2-one
CAS 216366-75-5C8H13NO2
(2S,3R)-3-Isopropyl-4-oxoazetidine-2-carboxylic acid chemical structure, C7H11NO3, CAS 172697-24-4
(2S,3R)-3-Isopropyl-4-oxoazetidine-2-carboxylic acid
CAS 172697-24-4C7H11NO3