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Murcko scaffold

2-Azetidinone scaffold

485 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
485
With full pages
48
Scaffold SMILES

O=C1CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Azetidinone page
Murcko scaffold O=C1CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 433 to 480 of 485 chemicals

(3R)-3-Amino-1-methylazetidin-2-one chemical structure, C4H8N2O, CAS 2165410-74-0
(3R)-3-Amino-1-methylazetidin-2-one
CAS 2165410-74-0C4H8N2O
(3R)-3-Aminoazetidin-2-one hydrochloride chemical structure, C3H7ClN2O, CAS 2227199-00-8
(3R)-3-Aminoazetidin-2-one hydrochloride
CAS 2227199-00-8C3H7ClN2O
(3S)-2-Oxoazetidine-3-carboxylic acid chemical structure, C4H5NO3, CAS 2165694-44-8
(3S)-2-Oxoazetidine-3-carboxylic acid
CAS 2165694-44-8C4H5NO3
4-[2-[(2-Methyl-2-methylsulfanylpropyl)amino]propyl]azetidin-2-one chemical structure, C11H22N2OS, CAS 2224453-65-8
4-[2-[(2-Methyl-2-methylsulfanylpropyl)amino]propyl]azetidin-2-one
CAS 2224453-65-8C11H22N2OS
(1-Ethyl-3-methyl-2-oxoazetidin-3-yl)methanesulfonyl fluoride chemical structure, C7H12FNO3S, CAS 2253638-55-8
(1-Ethyl-3-methyl-2-oxoazetidin-3-yl)methanesulfonyl fluoride
CAS 2253638-55-8C7H12FNO3S
3-(Aminomethyl)-1,3-dimethylazetidin-2-one chemical structure, C6H12N2O, CAS 2169138-89-8
3-(Aminomethyl)-1,3-dimethylazetidin-2-one
CAS 2169138-89-8C6H12N2O
3,3-Bis(chloromethyl)-1-methylazetidin-2-one chemical structure, C6H9Cl2NO, CAS 2219407-51-7
3,3-Bis(chloromethyl)-1-methylazetidin-2-one
CAS 2219407-51-7C6H9Cl2NO
3-(Chloromethyl)-1-ethyl-3-methylazetidin-2-one chemical structure, C7H12ClNO, CAS 2225144-92-1
3-(Chloromethyl)-1-ethyl-3-methylazetidin-2-one
CAS 2225144-92-1C7H12ClNO
3-(Chloromethyl)-3-methyl-1-(propan-2-yl)azetidin-2-one chemical structure, C8H14ClNO, CAS 2229324-44-9
3-(Chloromethyl)-3-methyl-1-(propan-2-yl)azetidin-2-one
CAS 2229324-44-9C8H14ClNO
3,3-Bis(chloromethyl)-1-ethylazetidin-2-one chemical structure, C7H11Cl2NO, CAS 2225136-45-6
3,3-Bis(chloromethyl)-1-ethylazetidin-2-one
CAS 2225136-45-6C7H11Cl2NO
3-(Chloromethyl)-3-methyl-1-(2,2,2-trifluoroethyl)azetidin-2-one chemical structure, C7H9ClF3NO, CAS 2225144-60-3
3-(Chloromethyl)-3-methyl-1-(2,2,2-trifluoroethyl)azetidin-2-one
CAS 2225144-60-3C7H9ClF3NO
3-(Aminomethyl)-1,3-dimethylazetidin-2-one hydrochloride chemical structure, C6H13ClN2O, CAS 2225146-71-2
3-(Aminomethyl)-1,3-dimethylazetidin-2-one hydrochloride
CAS 2225146-71-2C6H13ClN2O
3-(Aminomethyl)-1-ethyl-3-methylazetidin-2-one chemical structure, C7H14N2O, CAS 2229402-27-9
3-(Aminomethyl)-1-ethyl-3-methylazetidin-2-one
CAS 2229402-27-9C7H14N2O
3-(Aminomethyl)-1-isopropyl-3-methylazetidin-2-one chemical structure, C8H16N2O, CAS 2228423-36-5
3-(Aminomethyl)-1-isopropyl-3-methylazetidin-2-one
CAS 2228423-36-5C8H16N2O
3-(Chloromethyl)-3-methyl-1-(prop-2-en-1-yl)azetidin-2-one chemical structure, C8H12ClNO, CAS 2241131-23-5
3-(Chloromethyl)-3-methyl-1-(prop-2-en-1-yl)azetidin-2-one
CAS 2241131-23-5C8H12ClNO
(1,3-Dimethyl-2-oxoazetidin-3-yl)methanesulfonyl fluoride chemical structure, C6H10FNO3S, CAS 2243514-29-4
(1,3-Dimethyl-2-oxoazetidin-3-yl)methanesulfonyl fluoride
CAS 2243514-29-4C6H10FNO3S
(3R)-3-Aminoazetidin-2-one, acetic acid chemical structure, C5H10N2O3, CAS 1619921-80-0
(3R)-3-Aminoazetidin-2-one, acetic acid
CAS 1619921-80-0C5H10N2O3
4-[(Methylamino)methyl]-2-azetidinone chemical structure, C5H10N2O, CAS 2791272-00-7
4-[(Methylamino)methyl]-2-azetidinone
CAS 2791272-00-7C5H10N2O
3,3-Diethyl-4-oxo-2-azetidinyl butyrate chemical structure, C11H19NO3, CAS 2167962-65-2
3,3-Diethyl-4-oxo-2-azetidinyl butyrate
CAS 2167962-65-2C11H19NO3
1-(tert-Butyldimethylsilyl)-3-(hydroxymethyl)azetidin-2-one chemical structure, C10H21NO2Si, CAS 2791276-78-1
1-(tert-Butyldimethylsilyl)-3-(hydroxymethyl)azetidin-2-one
CAS 2791276-78-1C10H21NO2Si
N,N-Dibutyl-2-(4-oxoazetidin-2-yl)acetamide chemical structure, C13H24N2O2, CAS 2308314-22-7
N,N-Dibutyl-2-(4-oxoazetidin-2-yl)acetamide
CAS 2308314-22-7C13H24N2O2
1-Hydroxy-3,3-dimethylazetidin-2-one hydrochloride chemical structure, C5H10ClNO2, CAS 2460749-20-4
1-Hydroxy-3,3-dimethylazetidin-2-one hydrochloride
CAS 2460749-20-4C5H10ClNO2
4-(Aminomethyl)-4-methylazetidin-2-one chemical structure, C5H10N2O, CAS 2154149-68-3
4-(Aminomethyl)-4-methylazetidin-2-one
CAS 2154149-68-3C5H10N2O
4-[(Acetylsulfanyl)methyl]-4-methylazetidin-2-one chemical structure, C7H11NO2S, CAS 2470440-49-2
4-[(Acetylsulfanyl)methyl]-4-methylazetidin-2-one
CAS 2470440-49-2C7H11NO2S