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Murcko scaffold

1-(4-Phenyl-1,3-thiazol-2-yl)piperazine scaffold

82 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
82
With full pages
6
Scaffold SMILES

c1ccc(-c2csc(N3CCNCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(4-Phenyl-1,3-thiazol-2-yl)piperazine page
Murcko scaffold c1ccc(-c2csc(N3CCNCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 82 chemicals

1-(Methylsulfonyl)-4-(4-phenyl-1,3-thiazol-2-yl)piperazine chemical structure, C14H17N3O2S2, CAS 447428-28-6
1-(Methylsulfonyl)-4-(4-phenyl-1,3-thiazol-2-yl)piperazine
CAS 447428-28-6C14H17N3O2S2
Ethyl 4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperazine-1-carboxylate chemical structure, C17H21N3O3S, CAS 720669-05-6
Ethyl 4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperazine-1-carboxylate
CAS 720669-05-6C17H21N3O3S
1-(4-Phenyl-1,3-thiazol-2-yl)piperazine chemical structure, C13H15N3S, CAS 69389-14-6
1-(4-Phenyl-1,3-thiazol-2-yl)piperazine
CAS 69389-14-6C13H15N3S
Ethyl 4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1-piperazinecarboxylate chemical structure, C16H18FN3O2S, CAS 329071-76-3
Ethyl 4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-1-piperazinecarboxylate
CAS 329071-76-3C16H18FN3O2S
1-[4-(4-Fluoro-phenyl)-thiazol-2-yl]-4-methanesulfonyl-piperazine chemical structure, C14H16FN3O2S2, CAS 384859-21-6
1-[4-(4-Fluoro-phenyl)-thiazol-2-yl]-4-methanesulfonyl-piperazine
CAS 384859-21-6C14H16FN3O2S2
Ethyl 4-(4-(4-chlorophenyl)thiazol-2-yl)piperazine-1-carboxylate chemical structure, C16H18ClN3O2S, CAS 346662-91-7
Ethyl 4-(4-(4-chlorophenyl)thiazol-2-yl)piperazine-1-carboxylate
CAS 346662-91-7C16H18ClN3O2S
4-[4-(4-Chlorophenyl)-2-thiazolyl]-N,N-dimethyl-1-piperazinecarboxamide chemical structure, C16H19ClN4OS, CAS 309733-26-4
4-[4-(4-Chlorophenyl)-2-thiazolyl]-N,N-dimethyl-1-piperazinecarboxamide
CAS 309733-26-4C16H19ClN4OS
4-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-N-(2-methylpropyl)piperazine-1-carbothioamide chemical structure, C19H26N4S2, CAS 606087-77-8
4-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-N-(2-methylpropyl)piperazine-1-carbothioamide
CAS 606087-77-8C19H26N4S2
4-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-piperazine-1-carbothioic acid methylamide chemical structure, C16H20N4OS2, CAS 606088-54-4
4-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-piperazine-1-carbothioic acid methylamide
CAS 606088-54-4C16H20N4OS2
1-Methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperazine chemical structure, C14H17N3S, CAS 231963-95-4
1-Methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperazine
CAS 231963-95-4C14H17N3S
4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide chemical structure, C18H24N4S2, CAS 606087-84-7
4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide
CAS 606087-84-7C18H24N4S2
4-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-piperazine-1-carbothioic acid propylamide chemical structure, C18H24N4OS2, CAS 606088-87-3
4-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-piperazine-1-carbothioic acid propylamide
CAS 606088-87-3C18H24N4OS2
Oxiranecarboxamide,N-methoxy-N,3,3-trimethyl- chemical structure, C19H25N3O2S, CAS 606088-53-3
Oxiranecarboxamide,N-methoxy-N,3,3-trimethyl-
CAS 606088-53-3C19H25N3O2S
4-(4-Nitrophenyl)-2-(piperazin-1-yl)thiazole chemical structure, C13H14N4O2S, CAS 893764-01-7
4-(4-Nitrophenyl)-2-(piperazin-1-yl)thiazole
CAS 893764-01-7C13H14N4O2S
5-Methyl-2-(4-methylsulfonylpiperazin-1-yl)-4-phenyl-1,3-thiazole chemical structure, C15H19N3O2S2, CAS 904508-26-5
5-Methyl-2-(4-methylsulfonylpiperazin-1-yl)-4-phenyl-1,3-thiazole
CAS 904508-26-5C15H19N3O2S2
4-(4-Chlorophenyl)-2-(4-methylsulfonylpiperazin-1-yl)-1,3-thiazole chemical structure, C14H16ClN3O2S2, CAS 879759-81-6
4-(4-Chlorophenyl)-2-(4-methylsulfonylpiperazin-1-yl)-1,3-thiazole
CAS 879759-81-6C14H16ClN3O2S2
1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine chemical structure, C13H14FN3S, CAS 887625-25-4
1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine
CAS 887625-25-4C13H14FN3S
4-(2-(4-Methylpiperazin-1-yl)thiazol-4-yl)benzene-1,2-diol chemical structure, C14H17N3O2S, CAS 1351360-87-6
4-(2-(4-Methylpiperazin-1-yl)thiazol-4-yl)benzene-1,2-diol
CAS 1351360-87-6C14H17N3O2S
4-[2-(4-Methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzoic acid chemical structure, C15H17N3O2S, CAS 294622-47-2
4-[2-(4-Methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzoic acid
CAS 294622-47-2C15H17N3O2S
Benzoic acid, 4-[2-[4-(2-methoxyethyl)-1-piperazinyl]-4-thiazolyl]- chemical structure, C17H21N3O3S, CAS 860343-99-3
Benzoic acid, 4-[2-[4-(2-methoxyethyl)-1-piperazinyl]-4-thiazolyl]-
CAS 860343-99-3C17H21N3O3S
1-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-4-methylpiperazine chemical structure, C14H16ClN3S, CAS 923821-13-0
1-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-4-methylpiperazine
CAS 923821-13-0C14H16ClN3S
4-(4-Chlorophenyl)-2-piperazinyl-1,3-thiazole chemical structure, C13H14ClN3S, CAS 924843-35-6
4-(4-Chlorophenyl)-2-piperazinyl-1,3-thiazole
CAS 924843-35-6C13H14ClN3S
1-[4-(3,4-Dimethoxyphenyl)-2-thiazolyl]piperazine chemical structure, C15H19N3O2S, CAS 924861-70-1
1-[4-(3,4-Dimethoxyphenyl)-2-thiazolyl]piperazine
CAS 924861-70-1C15H19N3O2S
2-(Piperazin-1-yl)-4-(p-tolyl)thiazole hydrochloride chemical structure, C14H18ClN3S, CAS 1158487-74-1
2-(Piperazin-1-yl)-4-(p-tolyl)thiazole hydrochloride
CAS 1158487-74-1C14H18ClN3S