Murcko scaffold
Ring system with 3 rings and 20 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 6
- With full pages
- 2
Scaffold SMILES
O=c1[nH]cnc2c1NC(CCNc1ccccc1)CN2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
Ketotrexate
CAS 52196-22-2C21H27N7O6
p-((2-(2-Amino-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)ethyl)amino)benzoic acid
CAS 14047-44-0C15H18N6O3
Emofolin sodium
CAS 52386-42-2C21H25N7Na2O6
Sodium tetrahydrohomopteroate
CAS 33713-48-3C15H18N6NaO3+
Tetrahydrohomofolic acid
CAS 5786-82-3C20H25N7O6
C21H27N7NaO6
C21H27N7NaO6