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Murcko scaffold

3-(2,3-Dihydro-1H-indol-1-yl)-1-phenylpyrrolidine-2,5-dione scaffold

12 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 12
With full pages: 8

Scaffold SMILES

O=C1CC(N2CCc3ccccc32)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 3-(2,3-Dihydro-1H-indol-1-yl)-1-phenylpyrrolidine-2,5-dione page

Murcko scaffold O=C1CC(N2CCc3ccccc32)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-(2,3-Dihydro-1H-indol-1-yl)-1-(2-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C19H18N2O3, CAS 384369-32-8

3-(2,3-Dihydro-1H-indol-1-yl)-1-(2-methoxyphenyl)pyrrolidine-2,5-dione

CAS 384369-32-8C₁₉H₁₈N₂O₃

3-(2,3-Dihydro-1H-indol-1-yl)-1-(4-fluorophenyl)pyrrolidine-2,5-dione chemical structure, C18H15FN2O2, CAS 500197-66-0

3-(2,3-Dihydro-1H-indol-1-yl)-1-(4-fluorophenyl)pyrrolidine-2,5-dione

CAS 500197-66-0C₁₈H₁₅FN₂O₂

3-(2,3-Dihydro-1H-indol-1-yl)-1-(3-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C19H18N2O3, CAS 489444-33-9

3-(2,3-Dihydro-1H-indol-1-yl)-1-(3-methoxyphenyl)pyrrolidine-2,5-dione

CAS 489444-33-9C₁₉H₁₈N₂O₃

1-(3-Chloro-4-methylphenyl)-3-(2,3-dihydro-1H-indol-1-yl)pyrrolidine-2,5-dione chemical structure, C19H17ClN2O2, CAS 488861-58-1

1-(3-Chloro-4-methylphenyl)-3-(2,3-dihydro-1H-indol-1-yl)pyrrolidine-2,5-dione

CAS 488861-58-1C₁₉H₁₇ClN₂O₂

Ethyl 4-[3-(2,3-dihydro-1H-indol-1-yl)-2,5-dioxopyrrolidin-1-yl]benzoate chemical structure, C21H20N2O4, CAS 700849-70-3

Ethyl 4-[3-(2,3-dihydro-1H-indol-1-yl)-2,5-dioxopyrrolidin-1-yl]benzoate

CAS 700849-70-3C₂₁H₂₀N₂O₄

3-(2,3-Dihydro-1H-indol-1-yl)-1-(4-ethoxyphenyl)pyrrolidine-2,5-dione chemical structure, C20H20N2O3, CAS 701218-07-7

3-(2,3-Dihydro-1H-indol-1-yl)-1-(4-ethoxyphenyl)pyrrolidine-2,5-dione

CAS 701218-07-7C₂₀H₂₀N₂O₃

3-(2,3-Dihydro-1H-indol-1-yl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione chemical structure, C19H15F3N2O2, CAS 488744-69-0

3-(2,3-Dihydro-1H-indol-1-yl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione

CAS 488744-69-0C₁₉H₁₅F₃N₂O₂

3-(2,3-Dihydro-1H-indol-1-yl)-1-(2-ethylphenyl)pyrrolidine-2,5-dione chemical structure, C20H20N2O2, CAS 500270-00-8

3-(2,3-Dihydro-1H-indol-1-yl)-1-(2-ethylphenyl)pyrrolidine-2,5-dione

CAS 500270-00-8C₂₀H₂₀N₂O₂

1-(5-Chloro-2-methoxyphenyl)-3-(2,3-dihydro-1H-indol-1-yl)pyrrolidine-2,5-dione chemical structure, C19H17ClN2O3, CAS 500145-96-0

1-(5-Chloro-2-methoxyphenyl)-3-(2,3-dihydro-1H-indol-1-yl)pyrrolidine-2,5-dione

CAS 500145-96-0C₁₉H₁₇ClN₂O₃

3-(2,3-Dihydro-1H-indol-1-yl)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C19H18N2O3, CAS 500145-32-4

3-(2,3-Dihydro-1H-indol-1-yl)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione

CAS 500145-32-4C₁₉H₁₈N₂O₃

1-(3,5-Dichlorophenyl)-3-(2,3-dihydro-1H-indol-1-yl)dihydro-1H-pyrrole-2,5-dione chemical structure, C18H14Cl2N2O2, CAS 297149-75-8

1-(3,5-Dichlorophenyl)-3-(2,3-dihydro-1H-indol-1-yl)dihydro-1H-pyrrole-2,5-dione

CAS 297149-75-8C₁₈H₁₄Cl₂N₂O₂

3-(2,3-Dihydro-1H-indol-1-yl)-1-phenylpyrrolidine-2,5-dione chemical structure, C18H16N2O2, CAS 144040-35-7

3-(2,3-Dihydro-1H-indol-1-yl)-1-phenylpyrrolidine-2,5-dione

CAS 144040-35-7C₁₈H₁₆N₂O₂