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Murcko scaffold

Ring system with 4 rings and 22 atoms

25 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
25
With full pages
3
Scaffold SMILES

O=C1CC(c2c[nH]c3ccccc23)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(c2c[nH]c3ccccc23)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

3-(2-Methyl-1H-indol-3-yl)-1-phenylpyrrolidine-2,5-dione chemical structure, C19H16N2O2, CAS 6960-07-2
3-(2-Methyl-1H-indol-3-yl)-1-phenylpyrrolidine-2,5-dione
CAS 6960-07-2C19H16N2O2
3-(1H-Indol-3-yl)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C19H16N2O3, CAS 376385-13-6
3-(1H-Indol-3-yl)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione
CAS 376385-13-6C19H16N2O3
3-(1H-Indol-3-yl)-1-(4-methylphenyl)pyrrolidine-2,5-dione chemical structure, C19H16N2O2, CAS 376373-73-8
3-(1H-Indol-3-yl)-1-(4-methylphenyl)pyrrolidine-2,5-dione
CAS 376373-73-8C19H16N2O2
3-(1H-Indol-3-yl)-1-(3-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C19H16N2O3, CAS 376384-77-9
3-(1H-Indol-3-yl)-1-(3-methoxyphenyl)pyrrolidine-2,5-dione
CAS 376384-77-9C19H16N2O3
3-(1H-Indol-3-yl)-1-(2-methylphenyl)pyrrolidine-2,5-dione chemical structure, C19H16N2O2, CAS 375357-01-0
3-(1H-Indol-3-yl)-1-(2-methylphenyl)pyrrolidine-2,5-dione
CAS 375357-01-0C19H16N2O2
1-(4-Hydroxyphenyl)-3-(1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C18H14N2O3, CAS 433687-70-8
1-(4-Hydroxyphenyl)-3-(1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 433687-70-8C18H14N2O3
3-(1-Methyl-1H-indol-3-yl)-1-(2-methylphenyl)pyrrolidine-2,5-dione chemical structure, C20H18N2O2, CAS 496796-57-7
3-(1-Methyl-1H-indol-3-yl)-1-(2-methylphenyl)pyrrolidine-2,5-dione
CAS 496796-57-7C20H18N2O2
3-(1-Methylindol-3-yl)-1-(4-methylphenyl)pyrrolidine-2,5-dione chemical structure, C20H18N2O2, CAS 701225-45-8
3-(1-Methylindol-3-yl)-1-(4-methylphenyl)pyrrolidine-2,5-dione
CAS 701225-45-8C20H18N2O2
1-(4-Bromophenyl)-3-(1-propyl-1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C21H19BrN2O2, CAS 708280-34-6
1-(4-Bromophenyl)-3-(1-propyl-1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 708280-34-6C21H19BrN2O2
1-(4-Methoxyphenyl)-3-(1-propylindol-3-yl)pyrrolidine-2,5-dione chemical structure, C22H22N2O3, CAS 708279-79-2
1-(4-Methoxyphenyl)-3-(1-propylindol-3-yl)pyrrolidine-2,5-dione
CAS 708279-79-2C22H22N2O3
1-(2,6-Dichlorophenyl)-3-(1-methylindol-3-yl)pyrrolidine-2,5-dione chemical structure, C19H14Cl2N2O2, CAS 708291-70-7
1-(2,6-Dichlorophenyl)-3-(1-methylindol-3-yl)pyrrolidine-2,5-dione
CAS 708291-70-7C19H14Cl2N2O2
1-(2-Methoxyphenyl)-3-(1-methylindol-3-yl)pyrrolidine-2,5-dione chemical structure, C20H18N2O3, CAS 708996-76-3
1-(2-Methoxyphenyl)-3-(1-methylindol-3-yl)pyrrolidine-2,5-dione
CAS 708996-76-3C20H18N2O3
1-(3-Hydroxyphenyl)-3-(1-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C19H16N2O3, CAS 833432-67-0
1-(3-Hydroxyphenyl)-3-(1-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 833432-67-0C19H16N2O3
1-(3-Methoxyphenyl)-3-(1-propylindol-3-yl)pyrrolidine-2,5-dione chemical structure, C22H22N2O3, CAS 833436-68-3
1-(3-Methoxyphenyl)-3-(1-propylindol-3-yl)pyrrolidine-2,5-dione
CAS 833436-68-3C22H22N2O3
1-(4-Bromophenyl)-3-(1-ethyl-1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C20H17BrN2O2, CAS 836662-44-3
1-(4-Bromophenyl)-3-(1-ethyl-1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 836662-44-3C20H17BrN2O2
3-(1-Ethylindol-3-yl)-1-(4-hydroxyphenyl)pyrrolidine-2,5-dione chemical structure, C20H18N2O3, CAS 859661-76-0
3-(1-Ethylindol-3-yl)-1-(4-hydroxyphenyl)pyrrolidine-2,5-dione
CAS 859661-76-0C20H18N2O3
3-(5-Methoxy-1H-indol-3-yl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione chemical structure, C20H15F3N2O3, CAS 338962-79-1
3-(5-Methoxy-1H-indol-3-yl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione
CAS 338962-79-1C20H15F3N2O3
1-(2,4-Dichlorophenyl)-3-(1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C18H12Cl2N2O2, CAS 338962-81-5
1-(2,4-Dichlorophenyl)-3-(1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 338962-81-5C18H12Cl2N2O2
1-(2-Hydroxyphenyl)-3-(1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C18H14N2O3, CAS 433949-43-0
1-(2-Hydroxyphenyl)-3-(1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 433949-43-0C18H14N2O3
3-(1H-Indol-3-yl)-1-(3-methylphenyl)pyrrolidine-2,5-dione chemical structure, C19H16N2O2, CAS 374919-32-1
3-(1H-Indol-3-yl)-1-(3-methylphenyl)pyrrolidine-2,5-dione
CAS 374919-32-1C19H16N2O2
3-(1H-Indol-3-yl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione chemical structure, C19H13F3N2O2, CAS 338962-75-7
3-(1H-Indol-3-yl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione
CAS 338962-75-7C19H13F3N2O2
1-(3-Methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C20H18N2O3, CAS 4574-80-5
1-(3-Methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 4574-80-5C20H18N2O3
3-(2-Methyl-1H-indol-3-yl)-1-(4-nitrophenyl)pyrrolidine-2,5-dione chemical structure, C19H15N3O4, CAS 61123-24-8
3-(2-Methyl-1H-indol-3-yl)-1-(4-nitrophenyl)pyrrolidine-2,5-dione
CAS 61123-24-8C19H15N3O4
1-(4-Methoxyphenyl)-3-(2-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione chemical structure, C20H18N2O3, CAS 61123-25-9
1-(4-Methoxyphenyl)-3-(2-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione
CAS 61123-25-9C20H18N2O3