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Murcko scaffold

1,7-Naphthyridine scaffold

293 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
293
With full pages
32
Scaffold SMILES

c1cnc2cnccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,7-Naphthyridine page
Murcko scaffold c1cnc2cnccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 293 chemicals

6-Bromo-1,7-naphthyridine chemical structure, C8H5BrN2, CAS 2724300-02-9
6-Bromo-1,7-naphthyridine
CAS 2724300-02-9C8H5BrN2
6,8-Dibromo-1,7-naphthyridine chemical structure, C8H4Br2N2, CAS 223553-59-1
6,8-Dibromo-1,7-naphthyridine
CAS 223553-59-1C8H4Br2N2
3-Fluoro-1,7-naphthyridine chemical structure, C8H5FN2, CAS 1309379-33-6
3-Fluoro-1,7-naphthyridine
CAS 1309379-33-6C8H5FN2
2-Bromo-1,7-naphthyridine chemical structure, C8H5BrN2, CAS 54920-83-1
2-Bromo-1,7-naphthyridine
CAS 54920-83-1C8H5BrN2
6-Trifluoromethylsulfonyloxy-8-methoxy-1,7-naphthyridine chemical structure, C10H7F3N2O4S, CAS 207279-29-6
6-Trifluoromethylsulfonyloxy-8-methoxy-1,7-naphthyridine
CAS 207279-29-6C10H7F3N2O4S
2-Chloro-3-methyl-1,7-naphthyridine chemical structure, C9H7ClN2, CAS 1105191-93-2
2-Chloro-3-methyl-1,7-naphthyridine
CAS 1105191-93-2C9H7ClN2
5-Bromo-8-chloro-1,7-naphthyridine chemical structure, C8H4BrClN2, CAS 909649-06-5
5-Bromo-8-chloro-1,7-naphthyridine
CAS 909649-06-5C8H4BrClN2
8-Amino-1,7-naphthyridine-6-carboxylic acid chemical structure, C9H7N3O2, CAS 758726-20-4
8-Amino-1,7-naphthyridine-6-carboxylic acid
CAS 758726-20-4C9H7N3O2
1,7-Naphthyridine-5-carboxylic acid chemical structure, C9H6N2O2, CAS 1019115-06-0
1,7-Naphthyridine-5-carboxylic acid
CAS 1019115-06-0C9H6N2O2
8-Chloro-1,7-naphthyridine-6-carboxylic acid chemical structure, C9H5ClN2O2, CAS 1019111-25-1
8-Chloro-1,7-naphthyridine-6-carboxylic acid
CAS 1019111-25-1C9H5ClN2O2
5-Bromo-6-methyl-1,7-naphthyridine chemical structure, C9H7BrN2, CAS 1049030-25-2
5-Bromo-6-methyl-1,7-naphthyridine
CAS 1049030-25-2C9H7BrN2
1,7-Naphthyridine-6-carboxylic acid, 5-bromo- chemical structure, C9H5BrN2O2, CAS 1049130-81-5
1,7-Naphthyridine-6-carboxylic acid, 5-bromo-
CAS 1049130-81-5C9H5BrN2O2
4-Methyl-1,7-naphthyridine chemical structure, C9H8N2, CAS 54321-51-6
4-Methyl-1,7-naphthyridine
CAS 54321-51-6C9H8N2
6-Methyl-1,7-naphthyridin-8-amine chemical structure, C9H9N3, CAS 63029-22-1
6-Methyl-1,7-naphthyridin-8-amine
CAS 63029-22-1C9H9N3
Methyl 2-chloro-1,7-naphthyridine-3-carboxylate chemical structure, C10H7ClN2O2, CAS 1124194-70-2
Methyl 2-chloro-1,7-naphthyridine-3-carboxylate
CAS 1124194-70-2C10H7ClN2O2
1,7-Naphthyridin-6-yl trifluoromethanesulfonate chemical structure, C9H5F3N2O3S, CAS 864867-09-4
1,7-Naphthyridin-6-yl trifluoromethanesulfonate
CAS 864867-09-4C9H5F3N2O3S
2-Chloro-6-methoxy-1,7-naphthyridine chemical structure, C9H7ClN2O, CAS 27017-57-8
2-Chloro-6-methoxy-1,7-naphthyridine
CAS 27017-57-8C9H7ClN2O
2-Methyl-1,7-naphthyridin-4-amine chemical structure, C9H9N3, CAS 1245210-84-7
2-Methyl-1,7-naphthyridin-4-amine
CAS 1245210-84-7C9H9N3
8-Chloro-6-methyl-1,7-naphthyridine chemical structure, C9H7ClN2, CAS 1250444-30-4
8-Chloro-6-methyl-1,7-naphthyridine
CAS 1250444-30-4C9H7ClN2
2-Methoxy-1,7-naphthyridine chemical structure, C9H8N2O, CAS 35170-90-2
2-Methoxy-1,7-naphthyridine
CAS 35170-90-2C9H8N2O
Ethyl 1,7-naphthyridine-2-carboxylate chemical structure, C11H10N2O2, CAS 250674-53-4
Ethyl 1,7-naphthyridine-2-carboxylate
CAS 250674-53-4C11H10N2O2
8-Hydrazineyl-1,7-naphthyridine chemical structure, C8H8N4, CAS 89977-45-7
8-Hydrazineyl-1,7-naphthyridine
CAS 89977-45-7C8H8N4
1,7-Naphthyridine, 2,4-dihydrazinyl- chemical structure, C8H10N6, CAS 54920-79-5
1,7-Naphthyridine, 2,4-dihydrazinyl-
CAS 54920-79-5C8H10N6
4-Hydrazinyl-1,7-naphthyridine chemical structure, C8H8N4, CAS 99584-25-5
4-Hydrazinyl-1,7-naphthyridine
CAS 99584-25-5C8H8N4