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Murcko scaffold

1,7-Naphthyridine scaffold

293 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
293
With full pages
32
Scaffold SMILES

c1cnc2cnccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,7-Naphthyridine page
Murcko scaffold c1cnc2cnccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 293 chemicals

2-Bromo-8-chloro-1,7-naphthyridine chemical structure, C8H4BrClN2, CAS 1260666-72-5
2-Bromo-8-chloro-1,7-naphthyridine
CAS 1260666-72-5C8H4BrClN2
2,8-Dichloro-1,7-naphthyridine chemical structure, C8H4Cl2N2, CAS 1260664-21-8
2,8-Dichloro-1,7-naphthyridine
CAS 1260664-21-8C8H4Cl2N2
3,8-Dichloro-1,7-naphthyridine chemical structure, C8H4Cl2N2, CAS 1260672-65-8
3,8-Dichloro-1,7-naphthyridine
CAS 1260672-65-8C8H4Cl2N2
4-Bromo-8-chloro-1,7-naphthyridine chemical structure, C8H4BrClN2, CAS 1260671-82-6
4-Bromo-8-chloro-1,7-naphthyridine
CAS 1260671-82-6C8H4BrClN2
8-Chloro-1,7-naphthyridin-4-amine chemical structure, C8H6ClN3, CAS 1260664-35-4
8-Chloro-1,7-naphthyridin-4-amine
CAS 1260664-35-4C8H6ClN3
8-Chloro-3-fluoro-1,7-naphthyridine chemical structure, C8H4ClFN2, CAS 1393532-49-4
8-Chloro-3-fluoro-1,7-naphthyridine
CAS 1393532-49-4C8H4ClFN2
8-Chloro-3-(trifluoromethyl)-1,7-naphthyridine chemical structure, C9H4ClF3N2, CAS 1393570-24-5
8-Chloro-3-(trifluoromethyl)-1,7-naphthyridine
CAS 1393570-24-5C9H4ClF3N2
4-Chloro-8-methoxy-1,7-naphthyridine chemical structure, C9H7ClN2O, CAS 1823353-13-4
4-Chloro-8-methoxy-1,7-naphthyridine
CAS 1823353-13-4C9H7ClN2O
8-Amino-1,7-naphthyridine-5-carboxylic acid chemical structure, C9H7N3O2, CAS 1424941-74-1
8-Amino-1,7-naphthyridine-5-carboxylic acid
CAS 1424941-74-1C9H7N3O2
Ethyl 8-amino-1,7-naphthyridine-5-carboxylate chemical structure, C11H11N3O2, CAS 1609558-87-3
Ethyl 8-amino-1,7-naphthyridine-5-carboxylate
CAS 1609558-87-3C11H11N3O2
4-Ethynyl-1,7-naphthyridine chemical structure, C10H6N2, CAS 1824074-82-9
4-Ethynyl-1,7-naphthyridine
CAS 1824074-82-9C10H6N2
4-Vinyl-1,7-naphthyridine chemical structure, C10H8N2, CAS 1824194-82-2
4-Vinyl-1,7-naphthyridine
CAS 1824194-82-2C10H8N2
1,7-Naphthyridin-8-amine hydrochloride chemical structure, C8H8ClN3, CAS 1187932-59-7
1,7-Naphthyridin-8-amine hydrochloride
CAS 1187932-59-7C8H8ClN3
6-Chloro-1,7-naphthyridine chemical structure, C8H5ClN2, CAS 1309379-17-6
6-Chloro-1,7-naphthyridine
CAS 1309379-17-6C8H5ClN2
6-Bromo-2-methoxy-1,7-naphthyridine chemical structure, C9H7BrN2O, CAS 1246555-09-8
6-Bromo-2-methoxy-1,7-naphthyridine
CAS 1246555-09-8C9H7BrN2O
2-Bromo-6-chloro-1,7-naphthyridine chemical structure, C8H4BrClN2, CAS 1246549-09-6
2-Bromo-6-chloro-1,7-naphthyridine
CAS 1246549-09-6C8H4BrClN2
1,7-Naphthyridine-6-carboxylic acid chemical structure, C9H6N2O2, CAS 1368175-86-3
1,7-Naphthyridine-6-carboxylic acid
CAS 1368175-86-3C9H6N2O2
1-(1,7-Naphthyridin-8-yl)methanamine chemical structure, C9H9N3, CAS 1159827-41-4
1-(1,7-Naphthyridin-8-yl)methanamine
CAS 1159827-41-4C9H9N3
8-Chloro-1,7-naphthyridine-5-carboxylic acid chemical structure, C9H5ClN2O2, CAS 1424939-43-4
8-Chloro-1,7-naphthyridine-5-carboxylic acid
CAS 1424939-43-4C9H5ClN2O2
Methyl 8-chloro-1,7-naphthyridine-5-carboxylate chemical structure, C10H7ClN2O2, CAS 1424941-35-4
Methyl 8-chloro-1,7-naphthyridine-5-carboxylate
CAS 1424941-35-4C10H7ClN2O2
1,7-Naphthyridine-3-carbaldehyde chemical structure, C9H6N2O, CAS 1250443-54-9
1,7-Naphthyridine-3-carbaldehyde
CAS 1250443-54-9C9H6N2O
8-Chloro-1,7-naphthyridin-5-amine chemical structure, C8H6ClN3, CAS 123434-47-9
8-Chloro-1,7-naphthyridin-5-amine
CAS 123434-47-9C8H6ClN3
8-Amino-1,7-naphthyridine-5-carbonitrile chemical structure, C9H6N4, CAS 1706448-39-6
8-Amino-1,7-naphthyridine-5-carbonitrile
CAS 1706448-39-6C9H6N4
3,8-Dichloro-5-fluoro-1,7-naphthyridine chemical structure, C8H3Cl2FN2, CAS 1600511-82-7
3,8-Dichloro-5-fluoro-1,7-naphthyridine
CAS 1600511-82-7C8H3Cl2FN2