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Murcko scaffold

1,7-Naphthyridine scaffold

293 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
293
With full pages
32
Scaffold SMILES

c1cnc2cnccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,7-Naphthyridine page
Murcko scaffold c1cnc2cnccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 293 chemicals

Methyl 3-carbamoyl-1,7-naphthyridine-5-carboxylate chemical structure, C11H9N3O3, CAS 1646882-56-5
Methyl 3-carbamoyl-1,7-naphthyridine-5-carboxylate
CAS 1646882-56-5C11H9N3O3
Ethyl 5-bromo-1,7-naphthyridine-3-carboxylate chemical structure, C11H9BrN2O2, CAS 1646882-61-2
Ethyl 5-bromo-1,7-naphthyridine-3-carboxylate
CAS 1646882-61-2C11H9BrN2O2
5-Bromo-1,7-naphthyridine-3-carboxylic acid chemical structure, C9H5BrN2O2, CAS 1646882-64-5
5-Bromo-1,7-naphthyridine-3-carboxylic acid
CAS 1646882-64-5C9H5BrN2O2
5-Bromo-1,7-naphthyridine-3-carboxamide chemical structure, C9H6BrN3O, CAS 1646882-65-6
5-Bromo-1,7-naphthyridine-3-carboxamide
CAS 1646882-65-6C9H6BrN3O
5-Bromo-2-methyl-1,7-naphthyridine-3-carboxylic acid chemical structure, C10H7BrN2O2, CAS 1646882-67-8
5-Bromo-2-methyl-1,7-naphthyridine-3-carboxylic acid
CAS 1646882-67-8C10H7BrN2O2
5-Bromo-2-methyl-1,7-naphthyridine-3-carboxamide chemical structure, C10H8BrN3O, CAS 1646882-68-9
5-Bromo-2-methyl-1,7-naphthyridine-3-carboxamide
CAS 1646882-68-9C10H8BrN3O
5-Bromo-N-(2-(methylsulfonyl)ethyl)-1,7-naphthyridine-3-carboxamide chemical structure, C12H12BrN3O3S, CAS 1646882-69-0
5-Bromo-N-(2-(methylsulfonyl)ethyl)-1,7-naphthyridine-3-carboxamide
CAS 1646882-69-0C12H12BrN3O3S
Ethyl 5-bromo-2-methyl-1,7-naphthyridine-3-carboxylate chemical structure, C12H11BrN2O2, CAS 1646882-66-7
Ethyl 5-bromo-2-methyl-1,7-naphthyridine-3-carboxylate
CAS 1646882-66-7C12H11BrN2O2
8-Bromo-5-fluoro-3-(2-methylpropoxy)-1,7-naphthyridine chemical structure, C12H12BrFN2O, CAS 1600512-39-7
8-Bromo-5-fluoro-3-(2-methylpropoxy)-1,7-naphthyridine
CAS 1600512-39-7C12H12BrFN2O
5-Fluoro-1,7-naphthyridine chemical structure, C8H5FN2, CAS 1309379-35-8
5-Fluoro-1,7-naphthyridine
CAS 1309379-35-8C8H5FN2
8-Chloro-3-ethoxy-5-fluoro-1,7-naphthyridine chemical structure, C10H8ClFN2O, CAS 1600512-36-4
8-Chloro-3-ethoxy-5-fluoro-1,7-naphthyridine
CAS 1600512-36-4C10H8ClFN2O
8-Bromo-3-ethoxy-5-fluoro-1,7-naphthyridine chemical structure, C10H8BrFN2O, CAS 1600512-37-5
8-Bromo-3-ethoxy-5-fluoro-1,7-naphthyridine
CAS 1600512-37-5C10H8BrFN2O
8-Chloro-5-fluoro-3-isobutoxy-1,7-naphthyridine chemical structure, C12H12ClFN2O, CAS 1600512-38-6
8-Chloro-5-fluoro-3-isobutoxy-1,7-naphthyridine
CAS 1600512-38-6C12H12ClFN2O
Ethyl 8-chloro-1,7-naphthyridine-6-carboxylate chemical structure, C11H9ClN2O2, CAS 1660117-73-6
Ethyl 8-chloro-1,7-naphthyridine-6-carboxylate
CAS 1660117-73-6C11H9ClN2O2
8-Chloro-3-iodo-4-methoxy-1,7-naphthyridine chemical structure, C9H6ClIN2O, CAS 1812220-09-9
8-Chloro-3-iodo-4-methoxy-1,7-naphthyridine
CAS 1812220-09-9C9H6ClIN2O
8-Bromo-3-(but-2-ynyloxy)-1,7-naphthyridine chemical structure, C12H9BrN2O, CAS 1838674-90-0
8-Bromo-3-(but-2-ynyloxy)-1,7-naphthyridine
CAS 1838674-90-0C12H9BrN2O
3-Bromo-1,7-naphthyridin-8-amine chemical structure, C8H6BrN3, CAS 1838674-91-1
3-Bromo-1,7-naphthyridin-8-amine
CAS 1838674-91-1C8H6BrN3
Ethyl 4-chloro-6-methyl-1,7-naphthyridine-2-carboxylate chemical structure, C12H11ClN2O2, CAS 1884203-28-4
Ethyl 4-chloro-6-methyl-1,7-naphthyridine-2-carboxylate
CAS 1884203-28-4C12H11ClN2O2
4-Fluoro-1,7-naphthyridine chemical structure, C8H5FN2, CAS 1309379-34-7
4-Fluoro-1,7-naphthyridine
CAS 1309379-34-7C8H5FN2
4-Methoxy-1,7-naphthyridine chemical structure, C9H8N2O, CAS 35170-91-3
4-Methoxy-1,7-naphthyridine
CAS 35170-91-3C9H8N2O
8-Chloro-1,7-naphthyridine-3-carbaldehyde chemical structure, C9H5ClN2O, CAS 1956389-95-9
8-Chloro-1,7-naphthyridine-3-carbaldehyde
CAS 1956389-95-9C9H5ClN2O
4-Methoxy-8-methyl-1,7-naphthyridine-2-carboxylic acid chemical structure, C11H10N2O3, CAS 1421760-38-4
4-Methoxy-8-methyl-1,7-naphthyridine-2-carboxylic acid
CAS 1421760-38-4C11H10N2O3
Methyl 1,7-naphthyridine-3-carboxylate chemical structure, C10H8N2O2, CAS 1935402-75-7
Methyl 1,7-naphthyridine-3-carboxylate
CAS 1935402-75-7C10H8N2O2
6-Bromo-2-chloro-1,7-naphthyridine chemical structure, C8H4BrClN2, CAS 1246554-46-0
6-Bromo-2-chloro-1,7-naphthyridine
CAS 1246554-46-0C8H4BrClN2