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Murcko scaffold

1,7-Naphthyridine scaffold

293 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
293
With full pages
32
Scaffold SMILES

c1cnc2cnccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,7-Naphthyridine page
Murcko scaffold c1cnc2cnccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 293 chemicals

1,7-Naphthyridine chemical structure, C8H6N2, CAS 253-69-0
1,7-Naphthyridine
CAS 253-69-0C8H6N2
1,7-Naphthyridin-8-amine chemical structure, C8H7N3, CAS 17965-82-1
1,7-Naphthyridin-8-amine
CAS 17965-82-1C8H7N3
4-(1,7-Naphthyridin-8-ylamino)-4-oxobutanoic acid chemical structure, C12H11N3O3, CAS 396682-90-9
4-(1,7-Naphthyridin-8-ylamino)-4-oxobutanoic acid
CAS 396682-90-9C12H11N3O3
Acetamide, N-(8-(dimethylamine)-1,7-naphthyridin-6-yl)- chemical structure, C12H14N4O, CAS 106309-67-5
Acetamide, N-(8-(dimethylamine)-1,7-naphthyridin-6-yl)-
CAS 106309-67-5C12H14N4O
8-Methoxy-1,7-naphthyridin-6-amine chemical structure, C9H9N3O, CAS 55716-28-4
8-Methoxy-1,7-naphthyridin-6-amine
CAS 55716-28-4C9H9N3O
8-Bromo-1,7-naphthyridin-6-amine chemical structure, C8H6BrN3, CAS 5912-35-6
8-Bromo-1,7-naphthyridin-6-amine
CAS 5912-35-6C8H6BrN3
Ethyl 2-methyl-1,7-naphthyridine-3-carboxylate chemical structure, C12H12N2O2, CAS 55234-62-3
Ethyl 2-methyl-1,7-naphthyridine-3-carboxylate
CAS 55234-62-3C12H12N2O2
2-Amino-1,7-naphthyridine-3-carbonitrile chemical structure, C9H6N4, CAS 55234-65-6
2-Amino-1,7-naphthyridine-3-carbonitrile
CAS 55234-65-6C9H6N4
2-Amino-1,7-naphthyridine-3-carboxamide chemical structure, C9H8N4O, CAS 55234-67-8
2-Amino-1,7-naphthyridine-3-carboxamide
CAS 55234-67-8C9H8N4O
4-Bromo-1,7-naphthyridine chemical structure, C8H5BrN2, CAS 58680-40-3
4-Bromo-1,7-naphthyridine
CAS 58680-40-3C8H5BrN2
4-Chloro-1,7-naphthyridine chemical structure, C8H5ClN2, CAS 16287-97-1
4-Chloro-1,7-naphthyridine
CAS 16287-97-1C8H5ClN2
1,7-Naphthyridin-3-amine chemical structure, C8H7N3, CAS 58680-42-5
1,7-Naphthyridin-3-amine
CAS 58680-42-5C8H7N3
1,7-Naphthyridin-4-amine chemical structure, C8H7N3, CAS 58680-41-4
1,7-Naphthyridin-4-amine
CAS 58680-41-4C8H7N3
1,7-Naphthyridin-2-amine chemical structure, C8H7N3, CAS 54920-84-2
1,7-Naphthyridin-2-amine
CAS 54920-84-2C8H7N3
3-Bromo-1,7-naphthyridine chemical structure, C8H5BrN2, CAS 67967-05-9
3-Bromo-1,7-naphthyridine
CAS 67967-05-9C8H5BrN2
3-Chloro-1,7-naphthyridine chemical structure, C8H5ClN2, CAS 35170-89-9
3-Chloro-1,7-naphthyridine
CAS 35170-89-9C8H5ClN2
4-Chloro-2-methyl-1,7-naphthyridine chemical structure, C9H7ClN2, CAS 61319-98-0
4-Chloro-2-methyl-1,7-naphthyridine
CAS 61319-98-0C9H7ClN2
3,5-Dibromo-1,7-naphthyridine chemical structure, C8H4Br2N2, CAS 17965-77-4
3,5-Dibromo-1,7-naphthyridine
CAS 17965-77-4C8H4Br2N2
5-Bromo-1,7-naphthyridine chemical structure, C8H5BrN2, CAS 17965-76-3
5-Bromo-1,7-naphthyridine
CAS 17965-76-3C8H5BrN2
3,4-Dibromo-1,7-naphthyridine chemical structure, C8H4Br2N2, CAS 53454-39-0
3,4-Dibromo-1,7-naphthyridine
CAS 53454-39-0C8H4Br2N2
2-Methyl-1,7-naphthyridine chemical structure, C9H8N2, CAS 61523-57-7
2-Methyl-1,7-naphthyridine
CAS 61523-57-7C9H8N2
2,3-Dimethyl-1,7-naphthyridine chemical structure, C10H10N2, CAS 61523-58-8
2,3-Dimethyl-1,7-naphthyridine
CAS 61523-58-8C10H10N2
3-Methyl-1,7-naphthyridine chemical structure, C9H8N2, CAS 61523-59-9
3-Methyl-1,7-naphthyridine
CAS 61523-59-9C9H8N2
8-Chloro-(1,7)naphthyridine chemical structure, C8H5ClN2, CAS 13058-77-0
8-Chloro-(1,7)naphthyridine
CAS 13058-77-0C8H5ClN2