CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 17 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(C=C1SC(=O)NC1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=C1SC(=O)NC1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-(2,4-Dioxo(1,3-thiazolidin-5-ylidene))-N-(4-hydroxyphenyl)acetamide chemical structure, C11H8N2O4S, CAS 429640-30-2
2-(2,4-Dioxo(1,3-thiazolidin-5-ylidene))-N-(4-hydroxyphenyl)acetamide
CAS 429640-30-2C11H8N2O4S
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(3-methylphenyl)acetamide chemical structure, C12H10N2O3S, CAS 429640-82-4
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(3-methylphenyl)acetamide
CAS 429640-82-4C12H10N2O3S
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(3-hydroxyphenyl)acetamide chemical structure, C11H8N2O4S, CAS 429652-07-3
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(3-hydroxyphenyl)acetamide
CAS 429652-07-3C11H8N2O4S
(Z)-Ethyl 4-(2-(2,4-dioxothiazolidin-5-ylidene)acetamido)benzoate chemical structure, C14H12N2O5S, CAS 429650-55-5
(Z)-Ethyl 4-(2-(2,4-dioxothiazolidin-5-ylidene)acetamido)benzoate
CAS 429650-55-5C14H12N2O5S
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(2-hydroxyphenyl)acetamide chemical structure, C11H8N2O4S, CAS 429655-76-5
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(2-hydroxyphenyl)acetamide
CAS 429655-76-5C11H8N2O4S
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(2-methylphenyl)acetamide chemical structure, C12H10N2O3S, CAS 430443-01-9
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(2-methylphenyl)acetamide
CAS 430443-01-9C12H10N2O3S
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(4-methylphenyl)acetamide chemical structure, C12H10N2O3S, CAS 314260-09-8
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(4-methylphenyl)acetamide
CAS 314260-09-8C12H10N2O3S
2-[2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)acetylamino]benzoic acid chemical structure, C12H8N2O5S, CAS 314260-10-1
2-[2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)acetylamino]benzoic acid
CAS 314260-10-1C12H8N2O5S
(Z)-4-(2-(2,4-Dioxothiazolidin-5-ylidene)acetamido)benzoic acid chemical structure, C12H8N2O5S, CAS 378224-67-0
(Z)-4-(2-(2,4-Dioxothiazolidin-5-ylidene)acetamido)benzoic acid
CAS 378224-67-0C12H8N2O5S
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(4-methoxyphenyl)acetamide chemical structure, C12H10N2O4S, CAS 868152-94-7
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(4-methoxyphenyl)acetamide
CAS 868152-94-7C12H10N2O4S
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(4-sulfamoylphenyl)acetamide chemical structure, C11H9N3O5S2, CAS 430445-70-8
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(4-sulfamoylphenyl)acetamide
CAS 430445-70-8C11H9N3O5S2
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(3-methoxyphenyl)acetamide chemical structure, C12H10N2O4S, CAS 882240-42-8
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(3-methoxyphenyl)acetamide
CAS 882240-42-8C12H10N2O4S
(Z)-2-(2,4-Dioxothiazolidin-5-ylidene)-N-(2-methoxyphenyl)acetamide chemical structure, C12H10N2O4S, CAS 882240-44-0
(Z)-2-(2,4-Dioxothiazolidin-5-ylidene)-N-(2-methoxyphenyl)acetamide
CAS 882240-44-0C12H10N2O4S
(Z)-N-(4-Butylphenyl)-2-(2,4-dioxothiazolidin-5-ylidene)acetamide chemical structure, C15H16N2O3S, CAS 880796-37-2
(Z)-N-(4-Butylphenyl)-2-(2,4-dioxothiazolidin-5-ylidene)acetamide
CAS 880796-37-2C15H16N2O3S