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Murcko scaffold

Ring system with 3 rings and 24 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)N1CCN(CC=Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)N1CCN(CC=Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-(4-Methylphenyl)(4-(3-phenylprop-2-enyl)piperazinyl)formamide chemical structure, C21H25N3O, CAS 693805-74-2
N-(4-Methylphenyl)(4-(3-phenylprop-2-enyl)piperazinyl)formamide
CAS 693805-74-2C21H25N3O
N-Phenyl-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carboxamide chemical structure, C20H23N3O, CAS 289491-34-5
N-Phenyl-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carboxamide
CAS 289491-34-5C20H23N3O
N-(4-Chlorophenyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carboxamide chemical structure, C20H22ClN3O, CAS 401636-59-7
N-(4-Chlorophenyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carboxamide
CAS 401636-59-7C20H22ClN3O
N-(2-Methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide chemical structure, C21H25N3O, CAS 833436-43-4
N-(2-Methylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide
CAS 833436-43-4C21H25N3O
N-(2-Fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide chemical structure, C20H22FN3O, CAS 891003-41-1
N-(2-Fluorophenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide
CAS 891003-41-1C20H22FN3O
N-(2,5-Dimethylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide chemical structure, C22H27N3O, CAS 895652-85-4
N-(2,5-Dimethylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide
CAS 895652-85-4C22H27N3O
N-(3-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide chemical structure, C21H25N3O2, CAS 905431-02-9
N-(3-Methoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide
CAS 905431-02-9C21H25N3O2
N-(2-Ethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide chemical structure, C22H27N3O2, CAS 892767-97-4
N-(2-Ethoxyphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide
CAS 892767-97-4C22H27N3O2
N-(3,5-Dimethylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide chemical structure, C22H27N3O, CAS 893015-39-9
N-(3,5-Dimethylphenyl)-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carboxamide
CAS 893015-39-9C22H27N3O