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Murcko scaffold

Ring system with 3 rings and 16 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
15
With full pages
4
Scaffold SMILES

O=c1ccnc2scc(-c3ccccc3)n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc2scc(-c3ccccc3)n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

7-Methyl-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one chemical structure, C13H10N2OS, CAS 17649-34-2
7-Methyl-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
CAS 17649-34-2C13H10N2OS
7-Methyl-3-(4-methylphenyl)-[1,3]thiazolo[3,2-a]pyrimidin-5-one chemical structure, C14H12N2OS, CAS 23429-89-2
7-Methyl-3-(4-methylphenyl)-[1,3]thiazolo[3,2-a]pyrimidin-5-one
CAS 23429-89-2C14H12N2OS
3-(4-Chlorophenyl)-7-methyl-5H-pyrimido[2,1-b][1,3]thiazol-5-one chemical structure, C13H9ClN2OS, CAS 23429-91-6
3-(4-Chlorophenyl)-7-methyl-5H-pyrimido[2,1-b][1,3]thiazol-5-one
CAS 23429-91-6C13H9ClN2OS
Ethyl 5-oxo-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C15H12N2O3S, CAS 73644-76-5
Ethyl 5-oxo-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 73644-76-5C15H12N2O3S
7-(Chloromethyl)-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one chemical structure, C13H9ClN2OS, CAS 85811-56-9
7-(Chloromethyl)-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
CAS 85811-56-9C13H9ClN2OS
7-[[Bis(prop-2-enyl)amino]methyl]-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one chemical structure, C19H19N3OS, CAS 852664-93-8
7-[[Bis(prop-2-enyl)amino]methyl]-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one
CAS 852664-93-8C19H19N3OS
7-(Chloromethyl)-3-(4-chlorophenyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one chemical structure, C13H8Cl2N2OS, CAS 100003-85-8
7-(Chloromethyl)-3-(4-chlorophenyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
CAS 100003-85-8C13H8Cl2N2OS
5-Oxo-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylic acid chemical structure, C13H8N2O3S, CAS 446829-29-4
5-Oxo-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylic acid
CAS 446829-29-4C13H8N2O3S
N-(3-(7-Methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)isobutyramide chemical structure, C17H17N3O2S, CAS 1021039-58-6
N-(3-(7-Methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)isobutyramide
CAS 1021039-58-6C17H17N3O2S
N-(3-(7-Methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)-2-propylpentanamide chemical structure, C21H25N3O2S, CAS 1021039-64-4
N-(3-(7-Methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)-2-propylpentanamide
CAS 1021039-64-4C21H25N3O2S
N-(3-(6,7-Dimethyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)-2-methoxyacetamide chemical structure, C17H17N3O3S, CAS 1021073-92-6
N-(3-(6,7-Dimethyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)-2-methoxyacetamide
CAS 1021073-92-6C17H17N3O3S
N-(4-(7-Methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)methanesulfonamide chemical structure, C14H13N3O3S2, CAS 1172774-41-2
N-(4-(7-Methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)methanesulfonamide
CAS 1172774-41-2C14H13N3O3S2
N-(3-(6,7-Dimethyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)methanesulfonamide chemical structure, C15H15N3O3S2, CAS 1021074-34-9
N-(3-(6,7-Dimethyl-5-oxo-5H-thiazolo[3,2-a]pyrimidin-3-yl)phenyl)methanesulfonamide
CAS 1021074-34-9C15H15N3O3S2
3-(4-Methylphenyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylic acid chemical structure, C14H10N2O3S, CAS 446829-31-8
3-(4-Methylphenyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylic acid
CAS 446829-31-8C14H10N2O3S
6-Amino-7-methyl-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one chemical structure, C13H11N3OS, CAS 2197742-66-6
6-Amino-7-methyl-3-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
CAS 2197742-66-6C13H11N3OS