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Murcko scaffold

Ring system with 3 rings and 20 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
7
With full pages
4
Scaffold SMILES

O=C(C=Cc1ccccc1)c1ccc2c(c1)CCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)c1ccc2c(c1)CCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Dorsmanin A chemical structure, C20H20O4, CAS 162229-27-8
Dorsmanin A
CAS 162229-27-8C20H20O4
Xanthohumol B chemical structure, C21H22O6, CAS 189308-10-9
Xanthohumol B
CAS 189308-10-9C21H22O6
Helikrausichalcone chemical structure, C20H20O5, CAS 122585-71-1
Helikrausichalcone
CAS 122585-71-1C20H20O5
Cyclokuraridin chemical structure, C26H30O6, CAS 910459-02-8
Cyclokuraridin
CAS 910459-02-8C26H30O6
Isodehydrocycloxanthohumol hydrate chemical structure, C21H22O5, CAS 250603-94-2
Isodehydrocycloxanthohumol hydrate
CAS 250603-94-2C21H22O5
(2Z)-1-(5-Hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-yl)-3-phenylprop-2-en-1-one chemical structure, C20H20O3, CAS 51619-58-0
(2Z)-1-(5-Hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-yl)-3-phenylprop-2-en-1-one
CAS 51619-58-0C20H20O3
1-(3,4-Dihydro-3,5-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-phenyl-2-propen-1-one chemical structure, C20H20O4, CAS 61235-36-7
1-(3,4-Dihydro-3,5-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-phenyl-2-propen-1-one
CAS 61235-36-7C20H20O4