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Murcko scaffold

Ring system with 2 rings and 16 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
13
With full pages
3
Scaffold SMILES

O=C1CCC(C(=O)NCCc2cnc[nH]2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC(C(=O)NCCc2cnc[nH]2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Methyl N-(5-oxo-L-prolyl)-L-histidinate chemical structure, C12H16N4O4, CAS 25575-88-6
Methyl N-(5-oxo-L-prolyl)-L-histidinate
CAS 25575-88-6C12H16N4O4
N-(5-Oxo-L-prolyl)-L-histidinohydrazide chemical structure, C11H16N6O3, CAS 25575-89-7
N-(5-Oxo-L-prolyl)-L-histidinohydrazide
CAS 25575-89-7C11H16N6O3
Pyroglutamyl-histidyl-alanine chemical structure, C14H19N5O5, CAS 82780-19-6
Pyroglutamyl-histidyl-alanine
CAS 82780-19-6C14H19N5O5
Pyroglutamyl-3-methylhistidyl-glycine chemical structure, C14H19N5O5, CAS 82780-18-5
Pyroglutamyl-3-methylhistidyl-glycine
CAS 82780-18-5C14H19N5O5
3-(1H-Imidazol-4-yl)-2-[(5-oxo-pyrrolidine-2-carbonyl)-amino]-propionic acid methyl ester chemical structure, C12H16N4O4, CAS 1396963-73-7
3-(1H-Imidazol-4-yl)-2-[(5-oxo-pyrrolidine-2-carbonyl)-amino]-propionic acid methyl ester
CAS 1396963-73-7C12H16N4O4
Anorexigenic peptide chemical structure, C13H17N5O5, CAS 69275-10-1
Anorexigenic peptide
CAS 69275-10-1C13H17N5O5
5-Oxo-L-prolyl-L-histidine chemical structure, C11H14N4O4, CAS 32159-22-1
5-Oxo-L-prolyl-L-histidine
CAS 32159-22-1C11H14N4O4
5-Oxo-D-prolyl-L-histidylglycine chemical structure, C13H17N5O5, CAS 80817-86-3
5-Oxo-D-prolyl-L-histidylglycine
CAS 80817-86-3C13H17N5O5
pGlu-His-Gly amide trifluoro acetate salt chemical structure, C13H18N6O4, CAS 27058-74-8
pGlu-His-Gly amide trifluoro acetate salt
CAS 27058-74-8C13H18N6O4
L-Valinamide, 5-oxo-L-prolyl-L-histidyl- chemical structure, C16H24N6O4, CAS 27058-71-5
L-Valinamide, 5-oxo-L-prolyl-L-histidyl-
CAS 27058-71-5C16H24N6O4
(2S)-3-(1H-Imidazol-5-yl)-2-[(5-oxo-L-prolyl)amino]-1-(triaz-2-yn-2-ium-1-ylidene)propan-1-olate chemical structure, C11H13N7O3, CAS 51814-16-5
(2S)-3-(1H-Imidazol-5-yl)-2-[(5-oxo-L-prolyl)amino]-1-(triaz-2-yn-2-ium-1-ylidene)propan-1-olate
CAS 51814-16-5C11H13N7O3
H-Pyr-His-Glu-OH chemical structure, C16H21N5O7, CAS 141262-41-1
H-Pyr-His-Glu-OH
CAS 141262-41-1C16H21N5O7
pGlu-His-Glyamidetrifluoroacetatesalt chemical structure, C15H19F3N6O6
pGlu-His-Glyamidetrifluoroacetatesalt
C15H19F3N6O6