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Murcko scaffold

Ring system with 2 rings and 19 atoms

63 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
63
With full pages
5
Scaffold SMILES

O=C(CNc1ccccc1)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNc1ccccc1)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 63 chemicals

Ecabapide chemical structure, C20H25N3O4, CAS 104775-36-2
Ecabapide
CAS 104775-36-2C20H25N3O4
Benzamide, 3-((2-((2-(3,4-dimethoxyphenyl)ethyl)amino)-2-oxoethyl)amino)-, monohydrochloride chemical structure, C19H24ClN3O4, CAS 76001-14-4
Benzamide, 3-((2-((2-(3,4-dimethoxyphenyl)ethyl)amino)-2-oxoethyl)amino)-, monohydrochloride
CAS 76001-14-4C19H24ClN3O4
3-[[2-[2-(3,4-Dimethoxyphenyl)ethylamino]-2-oxoethyl]amino]benzamide chemical structure, C19H23N3O4, CAS 76001-09-7
3-[[2-[2-(3,4-Dimethoxyphenyl)ethylamino]-2-oxoethyl]amino]benzamide
CAS 76001-09-7C19H23N3O4
2-(3-Chloro-4-methyl-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide chemical structure, C20H25ClN2O5S, CAS 428489-67-2
2-(3-Chloro-4-methyl-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
CAS 428489-67-2C20H25ClN2O5S
2-(3-Chloro-4-methyl-N-methylsulfonylanilino)-N-(2-phenylethyl)acetamide chemical structure, C18H21ClN2O3S, CAS 363181-67-3
2-(3-Chloro-4-methyl-N-methylsulfonylanilino)-N-(2-phenylethyl)acetamide
CAS 363181-67-3C18H21ClN2O3S
2-(3,4-Dichloro-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide chemical structure, C19H22Cl2N2O5S, CAS 431986-27-5
2-(3,4-Dichloro-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
CAS 431986-27-5C19H22Cl2N2O5S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-(2-methoxy-N-methylsulfonylanilino)acetamide chemical structure, C20H26N2O6S, CAS 431999-38-1
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-(2-methoxy-N-methylsulfonylanilino)acetamide
CAS 431999-38-1C20H26N2O6S
2-[3,4-Dichloro(methylsulfonyl)anilino]-N-(2-phenylethyl)acetamide chemical structure, C17H18Cl2N2O3S, CAS 431983-06-1
2-[3,4-Dichloro(methylsulfonyl)anilino]-N-(2-phenylethyl)acetamide
CAS 431983-06-1C17H18Cl2N2O3S
2-(2-Methoxy-5-methyl-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide chemical structure, C20H26N2O5S, CAS 428466-15-3
2-(2-Methoxy-5-methyl-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide
CAS 428466-15-3C20H26N2O5S
2-(3-Methoxy-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide chemical structure, C19H24N2O5S, CAS 592468-72-9
2-(3-Methoxy-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide
CAS 592468-72-9C19H24N2O5S
2-(2-Bromo-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide chemical structure, C19H23BrN2O5S, CAS 333440-45-2
2-(2-Bromo-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
CAS 333440-45-2C19H23BrN2O5S
2-(4-Iodo-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide chemical structure, C18H21IN2O4S, CAS 449772-41-2
2-(4-Iodo-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide
CAS 449772-41-2C18H21IN2O4S
N~2~-(2,5-dichlorophenyl)-N~2~-(methylsulfonyl)-N-(2-phenylethyl)glycinamide chemical structure, C17H18Cl2N2O3S, CAS 529479-68-3
N~2~-(2,5-dichlorophenyl)-N~2~-(methylsulfonyl)-N-(2-phenylethyl)glycinamide
CAS 529479-68-3C17H18Cl2N2O3S
N~2~-(4-iodophenyl)-N~2~-(methylsulfonyl)-N-(2-phenylethyl)glycinamide chemical structure, C17H19IN2O3S, CAS 690691-89-5
N~2~-(4-iodophenyl)-N~2~-(methylsulfonyl)-N-(2-phenylethyl)glycinamide
CAS 690691-89-5C17H19IN2O3S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-(3-fluoro-N-methylsulfonylanilino)acetamide chemical structure, C19H23FN2O5S, CAS 701926-30-9
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-(3-fluoro-N-methylsulfonylanilino)acetamide
CAS 701926-30-9C19H23FN2O5S
2-(2,4-Dichloro-N-methylsulfonylanilino)-N-(2-phenylethyl)acetamide chemical structure, C17H18Cl2N2O3S, CAS 710971-40-7
2-(2,4-Dichloro-N-methylsulfonylanilino)-N-(2-phenylethyl)acetamide
CAS 710971-40-7C17H18Cl2N2O3S
2-(4-Bromo-3-methyl-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide chemical structure, C20H25BrN2O5S, CAS 824977-17-5
2-(4-Bromo-3-methyl-N-methylsulfonylanilino)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
CAS 824977-17-5C20H25BrN2O5S
2-(4-Ethoxy-N-methylsulfonylanilino)-N-(2-phenylethyl)acetamide chemical structure, C19H24N2O4S, CAS 333356-97-1
2-(4-Ethoxy-N-methylsulfonylanilino)-N-(2-phenylethyl)acetamide
CAS 333356-97-1C19H24N2O4S
2-[2-Ethoxy(methylsulfonyl)anilino]-N-(2-phenylethyl)acetamide chemical structure, C19H24N2O4S, CAS 333446-53-0
2-[2-Ethoxy(methylsulfonyl)anilino]-N-(2-phenylethyl)acetamide
CAS 333446-53-0C19H24N2O4S
2-[3-Chloro-4-methoxy(methylsulfonyl)anilino]-N-(2-phenylethyl)acetamide chemical structure, C18H21ClN2O4S, CAS 425613-91-8
2-[3-Chloro-4-methoxy(methylsulfonyl)anilino]-N-(2-phenylethyl)acetamide
CAS 425613-91-8C18H21ClN2O4S
N~2~-(3,5-dichlorophenyl)-N~2~-(methylsulfonyl)-N~1~-(2-phenylethyl)glycinamide chemical structure, C17H18Cl2N2O3S, CAS 6223-18-3
N~2~-(3,5-dichlorophenyl)-N~2~-(methylsulfonyl)-N~1~-(2-phenylethyl)glycinamide
CAS 6223-18-3C17H18Cl2N2O3S
2-(4-Methoxy-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide chemical structure, C19H24N2O5S, CAS 6385-28-0
2-(4-Methoxy-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide
CAS 6385-28-0C19H24N2O5S
2-(3-Bromo-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide chemical structure, C18H21BrN2O4S, CAS 335208-24-7
2-(3-Bromo-N-methylsulfonylanilino)-N-[2-(4-methoxyphenyl)ethyl]acetamide
CAS 335208-24-7C18H21BrN2O4S
N-[2-(4-Methoxyphenyl)ethyl]-2-(3-methyl-N-methylsulfonylanilino)acetamide chemical structure, C19H24N2O4S, CAS 367962-59-2
N-[2-(4-Methoxyphenyl)ethyl]-2-(3-methyl-N-methylsulfonylanilino)acetamide
CAS 367962-59-2C19H24N2O4S