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Murcko scaffold

Ring system with 3 rings and 19 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
19
With full pages
3
Scaffold SMILES

c1ccc(Nc2nccc(N3CCCCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nccc(N3CCCCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-N-Methyl-6-(4-methylpiperidin-1-yl)-5-nitro-2-N-phenylpyrimidine-2,4-diamine chemical structure, C17H22N6O2, CAS 577999-39-4
2-N-Methyl-6-(4-methylpiperidin-1-yl)-5-nitro-2-N-phenylpyrimidine-2,4-diamine
CAS 577999-39-4C17H22N6O2
2-N-Methyl-5-nitro-2-N-phenyl-6-piperidin-1-ylpyrimidine-2,4-diamine chemical structure, C16H20N6O2, CAS 673489-27-5
2-N-Methyl-5-nitro-2-N-phenyl-6-piperidin-1-ylpyrimidine-2,4-diamine
CAS 673489-27-5C16H20N6O2
N2-(4-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-5-nitropyrimidine-2,4-diamine chemical structure, C17H22N6O3, CAS 674356-77-5
N2-(4-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-5-nitropyrimidine-2,4-diamine
CAS 674356-77-5C17H22N6O3
6-(4-Methylpiperidin-1-yl)-5-nitro-N2-(p-tolyl)pyrimidine-2,4-diamine chemical structure, C17H22N6O2, CAS 673493-90-8
6-(4-Methylpiperidin-1-yl)-5-nitro-N2-(p-tolyl)pyrimidine-2,4-diamine
CAS 673493-90-8C17H22N6O2
2-N-Methyl-6-(3-methylpiperidin-1-yl)-5-nitro-2-N-phenylpyrimidine-2,4-diamine chemical structure, C17H22N6O2, CAS 713092-42-3
2-N-Methyl-6-(3-methylpiperidin-1-yl)-5-nitro-2-N-phenylpyrimidine-2,4-diamine
CAS 713092-42-3C17H22N6O2
N2-(4-methoxyphenyl)-6-(3-methylpiperidin-1-yl)-5-nitropyrimidine-2,4-diamine chemical structure, C17H22N6O3, CAS 716341-75-2
N2-(4-methoxyphenyl)-6-(3-methylpiperidin-1-yl)-5-nitropyrimidine-2,4-diamine
CAS 716341-75-2C17H22N6O3
3,3-Dimethyl-N-[4-[(4-methyl-6-piperidin-1-ylpyrimidin-2-yl)amino]phenyl]butanamide chemical structure, C22H31N5O, CAS 923245-37-8
3,3-Dimethyl-N-[4-[(4-methyl-6-piperidin-1-ylpyrimidin-2-yl)amino]phenyl]butanamide
CAS 923245-37-8C22H31N5O
3-[1-[5-Nitro-2-(3-nitroanilino)pyrimidin-4-yl]piperidin-2-yl]propan-1-ol chemical structure, C18H22N6O5, CAS 514831-68-6
3-[1-[5-Nitro-2-(3-nitroanilino)pyrimidin-4-yl]piperidin-2-yl]propan-1-ol
CAS 514831-68-6C18H22N6O5
1-[2-(4-Chloroanilino)-5-nitropyrimidin-4-yl]piperidin-3-ol chemical structure, C15H16ClN5O3, CAS 514832-58-7
1-[2-(4-Chloroanilino)-5-nitropyrimidin-4-yl]piperidin-3-ol
CAS 514832-58-7C15H16ClN5O3
1-[2-(4-Chloroanilino)-5-nitropyrimidin-4-yl]piperidin-4-ol chemical structure, C15H16ClN5O3, CAS 514834-73-2
1-[2-(4-Chloroanilino)-5-nitropyrimidin-4-yl]piperidin-4-ol
CAS 514834-73-2C15H16ClN5O3
3-Methyl-N-(4-{[4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl]amino}phenyl)butanamide chemical structure, C21H29N5O, CAS 946369-67-1
3-Methyl-N-(4-{[4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl]amino}phenyl)butanamide
CAS 946369-67-1C21H29N5O
N-(4-{[4-Methyl-6-(piperidin-1-yl)pyrimidin-2-yl]amino}phenyl)butanamide chemical structure, C20H27N5O, CAS 946369-64-8
N-(4-{[4-Methyl-6-(piperidin-1-yl)pyrimidin-2-yl]amino}phenyl)butanamide
CAS 946369-64-8C20H27N5O
N-(4-{[4-Methyl-6-(piperidin-1-yl)pyrimidin-2-yl]amino}phenyl)pentanamide chemical structure, C21H29N5O, CAS 946295-42-7
N-(4-{[4-Methyl-6-(piperidin-1-yl)pyrimidin-2-yl]amino}phenyl)pentanamide
CAS 946295-42-7C21H29N5O
4-Methyl-5-nitro-6-(piperidin-1-yl)-N-(p-tolyl)pyrimidin-2-amine chemical structure, C17H21N5O2, CAS 1209543-62-3
4-Methyl-5-nitro-6-(piperidin-1-yl)-N-(p-tolyl)pyrimidin-2-amine
CAS 1209543-62-3C17H21N5O2
N-(4-Ethoxyphenyl)-4-methyl-5-nitro-6-(piperidin-1-yl)pyrimidin-2-amine chemical structure, C18H23N5O3, CAS 1211659-59-4
N-(4-Ethoxyphenyl)-4-methyl-5-nitro-6-(piperidin-1-yl)pyrimidin-2-amine
CAS 1211659-59-4C18H23N5O3
N1-(4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl)benzene-1,4-diamine chemical structure, C16H21N5, CAS 1706441-77-1
N1-(4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl)benzene-1,4-diamine
CAS 1706441-77-1C16H21N5
N-(1-(2-((2-Nitrophenyl)amino)pyrimidin-4-yl)piperidin-3-yl)propane-1-sulfonamide chemical structure, C18H24N6O4S, CAS 1538605-62-7
N-(1-(2-((2-Nitrophenyl)amino)pyrimidin-4-yl)piperidin-3-yl)propane-1-sulfonamide
CAS 1538605-62-7C18H24N6O4S
tert-Butyl (1-(2-((2-nitrophenyl)amino)pyrimidin-4-yl)piperidin-3-yl)carbamate chemical structure, C20H26N6O4, CAS 1538605-61-6
tert-Butyl (1-(2-((2-nitrophenyl)amino)pyrimidin-4-yl)piperidin-3-yl)carbamate
CAS 1538605-61-6C20H26N6O4
N-[1-[2-(2-Aminoanilino)pyrimidin-4-yl]piperidin-3-yl]propane-1-sulfonamide chemical structure, C18H26N6O2S, CAS 1538605-63-8
N-[1-[2-(2-Aminoanilino)pyrimidin-4-yl]piperidin-3-yl]propane-1-sulfonamide
CAS 1538605-63-8C18H26N6O2S