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Murcko scaffold

N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-phenoxyacetamide scaffold

41 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
41
With full pages
15
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc2c(c1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-phenoxyacetamide page
Murcko scaffold O=C(COc1ccccc1)Nc1ccc2c(c1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

2-(2,4-Dichlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)propanamide chemical structure, C17H15Cl2NO4, CAS 346596-87-0
2-(2,4-Dichlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)propanamide
CAS 346596-87-0C17H15Cl2NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2,3-dimethylphenoxy)acetamide chemical structure, C18H19NO4, CAS 433245-75-1
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2,3-dimethylphenoxy)acetamide
CAS 433245-75-1C18H19NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3-methylphenoxy)acetamide chemical structure, C17H17NO4, CAS 301306-83-2
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3-methylphenoxy)acetamide
CAS 301306-83-2C17H17NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(4-methoxyphenoxy)acetamide chemical structure, C17H17NO5, CAS 301306-84-3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(4-methoxyphenoxy)acetamide
CAS 301306-84-3C17H17NO5
2-(4-Chloro-3-methylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C17H16ClNO4, CAS 301306-89-8
2-(4-Chloro-3-methylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 301306-89-8C17H16ClNO4
2-(3-Chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C16H14ClNO4, CAS 6047-19-4
2-(3-Chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 6047-19-4C16H14ClNO4
2-(2-tert-Butylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C20H23NO4, CAS 301307-11-9
2-(2-tert-Butylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 301307-11-9C20H23NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2,4-dimethylphenoxy)acetamide chemical structure, C18H19NO4, CAS 354156-86-8
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2,4-dimethylphenoxy)acetamide
CAS 354156-86-8C18H19NO4
2-(4-Chloro-2-methylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C17H16ClNO4, CAS 420812-84-6
2-(4-Chloro-2-methylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 420812-84-6C17H16ClNO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3-methoxyphenoxy)acetamide chemical structure, C17H17NO5, CAS 352648-94-3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3-methoxyphenoxy)acetamide
CAS 352648-94-3C17H17NO5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3,5-dimethylphenoxy)acetamide chemical structure, C18H19NO4, CAS 443903-38-6
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3,5-dimethylphenoxy)acetamide
CAS 443903-38-6C18H19NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2-methylphenoxy)acetamide chemical structure, C17H17NO4, CAS 299955-84-3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2-methylphenoxy)acetamide
CAS 299955-84-3C17H17NO4
2-(4-tert-Butylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C20H23NO4, CAS 352652-29-0
2-(4-tert-Butylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 352652-29-0C20H23NO4
2-(4-Chloro-3,5-dimethylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C18H18ClNO4, CAS 425372-80-1
2-(4-Chloro-3,5-dimethylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 425372-80-1C18H18ClNO4
2-(4-Chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylpropanamide chemical structure, C18H18ClNO4, CAS 431906-26-2
2-(4-Chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylpropanamide
CAS 431906-26-2C18H18ClNO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2-methoxyphenoxy)acetamide chemical structure, C17H17NO5, CAS 352649-21-9
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2-methoxyphenoxy)acetamide
CAS 352649-21-9C17H17NO5
2-(2,5-Dichlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C16H13Cl2NO4, CAS 301307-10-8
2-(2,5-Dichlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 301307-10-8C16H13Cl2NO4
2-(2,4-Dichlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C16H13Cl2NO4, CAS 347322-28-5
2-(2,4-Dichlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 347322-28-5C16H13Cl2NO4
2-(4-Bromo-2,6-dimethylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C18H18BrNO4, CAS 449752-46-9
2-(4-Bromo-2,6-dimethylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 449752-46-9C18H18BrNO4
2-(2-Bromo-4-methylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C17H16BrNO4, CAS 424796-69-0
2-(2-Bromo-4-methylphenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 424796-69-0C17H16BrNO4
2-(2-Bromo-4-chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C16H13BrClNO4, CAS 351977-50-9
2-(2-Bromo-4-chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 351977-50-9C16H13BrClNO4
2-(2-Chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C16H14ClNO4, CAS 5802-51-7
2-(2-Chlorophenoxy)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 5802-51-7C16H14ClNO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3-ethylphenoxy)acetamide chemical structure, C18H19NO4, CAS 634161-65-2
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(3-ethylphenoxy)acetamide
CAS 634161-65-2C18H19NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2,3,5-trimethylphenoxy)acetamide chemical structure, C19H21NO4, CAS 690988-17-1
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(2,3,5-trimethylphenoxy)acetamide
CAS 690988-17-1C19H21NO4