CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
16
With full pages
13
Scaffold SMILES

O=C(CCc1ccccc1)Nc1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1ccccc1)Nc1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Phenylalanine beta-naphthylamide chemical structure, C19H18N2O, CAS 740-57-8
Phenylalanine beta-naphthylamide
CAS 740-57-8C19H18N2O
(S)-2-Amino-3-(p-hydroxyphenyl)-N-(2-naphthyl)propionamide chemical structure, C19H18N2O2, CAS 4357-95-3
(S)-2-Amino-3-(p-hydroxyphenyl)-N-(2-naphthyl)propionamide
CAS 4357-95-3C19H18N2O2
Glycyl-N-2-naphthalenyl-L-phenylalaninamide chemical structure, C21H21N3O2, CAS 21438-66-4
Glycyl-N-2-naphthalenyl-L-phenylalaninamide
CAS 21438-66-4C21H21N3O2
Guanidinophenylalanine-2-naphthylamide chemical structure, C20H21N5O, CAS 115336-09-9
Guanidinophenylalanine-2-naphthylamide
CAS 115336-09-9C20H21N5O
5-[[2-[[2-[[1-(Naphthalen-2-ylamino)-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid chemical structure, C28H30N4O6, CAS 55145-12-5
5-[[2-[[2-[[1-(Naphthalen-2-ylamino)-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid
CAS 55145-12-5C28H30N4O6
4-Amino-5-[[2-[[1-[(4-methoxynaphthalen-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid chemical structure, C27H30N4O6, CAS 100940-58-7
4-Amino-5-[[2-[[1-[(4-methoxynaphthalen-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid
CAS 100940-58-7C27H30N4O6
5-[[1-[[1-[[1-[(4-Methoxynaphthalen-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid chemical structure, C31H36N4O7, CAS 79642-99-2
5-[[1-[[1-[[1-[(4-Methoxynaphthalen-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
CAS 79642-99-2C31H36N4O7
L-Seryl-L-tyrosine 2-naphthylamide chemical structure, C22H23N3O4, CAS 24008-82-0
L-Seryl-L-tyrosine 2-naphthylamide
CAS 24008-82-0C22H23N3O4
(2S)-2-[(2-Aminoacetyl)amino]-N-(4-methoxynaphthalen-2-yl)-3-phenylpropanamide chemical structure, C22H23N3O3
(2S)-2-[(2-Aminoacetyl)amino]-N-(4-methoxynaphthalen-2-yl)-3-phenylpropanamide
C22H23N3O3
N-Glutaryl-L-phenylalanine 2-naphthylamide chemical structure, C24H24N2O4, CAS 17479-62-8
N-Glutaryl-L-phenylalanine 2-naphthylamide
CAS 17479-62-8C24H24N2O4
N-(4-Methoxynaphthalen-2-yl)-L-phenylalaninamide chemical structure, C20H20N2O2, CAS 60285-95-2
N-(4-Methoxynaphthalen-2-yl)-L-phenylalaninamide
CAS 60285-95-2C20H20N2O2
H-Gly-Phe-4MbetaNA chemical structure, C22H23N3O3, CAS 168914-50-9
H-Gly-Phe-4MbetaNA
CAS 168914-50-9C22H23N3O3
3-[4-(1-Hydroxy-3-oxobutyl)phenyl]-N-(naphthalen-2-yl)propanamide chemical structure, C23H23NO3, CAS 682354-64-9
3-[4-(1-Hydroxy-3-oxobutyl)phenyl]-N-(naphthalen-2-yl)propanamide
CAS 682354-64-9C23H23NO3
H-Ala-Ala-Phe-NA chemical structure, C25H28N4O3, CAS 78497-23-1
H-Ala-Ala-Phe-NA
CAS 78497-23-1C25H28N4O3
Ala-Ala-Phe 4-methoxy-beta-naphthylamide chemical structure, C26H30N4O4, CAS 100900-09-2
Ala-Ala-Phe 4-methoxy-beta-naphthylamide
CAS 100900-09-2C26H30N4O4
(S)-2-(2-Aminoacetamido)-N-(naphthalen-2-yl)-3-phenylpropanamide 2,2,2-trifluoroacetate chemical structure, C23H22F3N3O4, CAS 109057-30-9
(S)-2-(2-Aminoacetamido)-N-(naphthalen-2-yl)-3-phenylpropanamide 2,2,2-trifluoroacetate
CAS 109057-30-9C23H22F3N3O4