Murcko scaffold
2-((1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-phenylacetamide scaffold
218 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 23
- Chemicals
- 218
- With full pages
- 8
Scaffold SMILES
O=C(CSC1=NS(=O)(=O)c2ccccc2N1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 218 chemicals
![2-((1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(2-methoxyphenyl)acetamide chemical structure, C16H15N3O4S2, CAS 896686-18-3](/s/ZRXPPKGYRRQCLA-UHFFFAOYSA-N.svg)
2-((1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(2-methoxyphenyl)acetamide
CAS 896686-18-3C16H15N3O4S2
![N-(4-Acetylphenyl)-2-[(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]acetamide chemical structure, C17H15N3O4S2, CAS 896685-58-8](/s/JJPFGSUOLMDRHU-UHFFFAOYSA-N.svg)
N-(4-Acetylphenyl)-2-[(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]acetamide
CAS 896685-58-8C17H15N3O4S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-phenylacetamide chemical structure, C15H12FN3O3S2, CAS 886952-83-6](/s/PACLCXSRVKWDND-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-phenylacetamide
CAS 886952-83-6C15H12FN3O3S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(o-tolyl)acetamide chemical structure, C16H14FN3O3S2, CAS 886952-86-9](/s/NVTXSEQSWUHHIP-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(o-tolyl)acetamide
CAS 886952-86-9C16H14FN3O3S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(m-tolyl)acetamide chemical structure, C16H14FN3O3S2, CAS 886952-91-6](/s/KIUOMSZUOMDXDL-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(m-tolyl)acetamide
CAS 886952-91-6C16H14FN3O3S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(p-tolyl)acetamide chemical structure, C16H14FN3O3S2, CAS 886952-96-1](/s/FOBWMZKHMXMXGE-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(p-tolyl)acetamide
CAS 886952-96-1C16H14FN3O3S2
![N-(2,3-Dimethylphenyl)-2-[(7-fluoro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]acetamide chemical structure, C17H16FN3O3S2, CAS 886953-05-5](/s/XHSRPULACHUXCB-UHFFFAOYSA-N.svg)
N-(2,3-Dimethylphenyl)-2-[(7-fluoro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]acetamide
CAS 886953-05-5C17H16FN3O3S2
![N-(2,5-Dimethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C17H16FN3O3S2, CAS 886953-13-5](/s/PVTFZFRREHZBRT-UHFFFAOYSA-N.svg)
N-(2,5-Dimethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886953-13-5C17H16FN3O3S2
![N-(2,4-Dimethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C17H16FN3O3S2, CAS 886953-21-5](/s/UAVZWCNSRGMPKT-UHFFFAOYSA-N.svg)
N-(2,4-Dimethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886953-21-5C17H16FN3O3S2
![N-(3,5-Dimethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C17H16FN3O3S2, CAS 886953-29-3](/s/DCYWXTZVURMLLD-UHFFFAOYSA-N.svg)
N-(3,5-Dimethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886953-29-3C17H16FN3O3S2
![2-[(7-Fluoro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C18H18FN3O3S2, CAS 886953-39-5](/s/XTPJZNLBGGRWON-UHFFFAOYSA-N.svg)
2-[(7-Fluoro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]-N-(2,4,6-trimethylphenyl)acetamide
CAS 886953-39-5C18H18FN3O3S2
![N-(4-Ethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C17H16FN3O3S2, CAS 886953-49-7](/s/RTDLZBJTUHVFLI-UHFFFAOYSA-N.svg)
N-(4-Ethylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886953-49-7C17H16FN3O3S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(2-fluorophenyl)acetamide chemical structure, C15H11F2N3O3S2, CAS 886953-64-6](/s/VFXDXEYDAHBDCT-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(2-fluorophenyl)acetamide
CAS 886953-64-6C15H11F2N3O3S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-fluorophenyl)acetamide chemical structure, C15H11F2N3O3S2, CAS 886953-69-1](/s/IGQOGVZVOJSNAT-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-fluorophenyl)acetamide
CAS 886953-69-1C15H11F2N3O3S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(4-fluorophenyl)acetamide chemical structure, C15H11F2N3O3S2, CAS 886953-74-8](/s/INQSSANZAMKKEP-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(4-fluorophenyl)acetamide
CAS 886953-74-8C15H11F2N3O3S2
![N-(3-Chlorophenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C15H11ClFN3O3S2, CAS 886953-84-0](/s/MOHNVTZQMUAGNT-UHFFFAOYSA-N.svg)
N-(3-Chlorophenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886953-84-0C15H11ClFN3O3S2
![N-(4-Chlorophenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C15H11ClFN3O3S2, CAS 886953-94-2](/s/BKFXZMKMLXZYSU-UHFFFAOYSA-N.svg)
N-(4-Chlorophenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886953-94-2C15H11ClFN3O3S2
![N-(2,4-Difluorophenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C15H10F3N3O3S2, CAS 886954-14-9](/s/BRCZIXQHYHQXMQ-UHFFFAOYSA-N.svg)
N-(2,4-Difluorophenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886954-14-9C15H10F3N3O3S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-methoxyphenyl)acetamide chemical structure, C16H14FN3O4S2, CAS 886954-54-7](/s/ZTNHUVKFRQNQOG-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-methoxyphenyl)acetamide
CAS 886954-54-7C16H14FN3O4S2
![2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(4-methoxyphenyl)acetamide chemical structure, C16H14FN3O4S2, CAS 886954-64-9](/s/SJOSWMIZGXDMSM-UHFFFAOYSA-N.svg)
2-((7-Fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(4-methoxyphenyl)acetamide
CAS 886954-64-9C16H14FN3O4S2
![N-(2-Ethoxyphenyl)-2-[(7-fluoro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]acetamide chemical structure, C17H16FN3O4S2, CAS 886954-74-1](/s/NFCZHXHODNNDCB-UHFFFAOYSA-N.svg)
N-(2-Ethoxyphenyl)-2-[(7-fluoro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]acetamide
CAS 886954-74-1C17H16FN3O4S2
![N-(4-Ethoxyphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C17H16FN3O4S2, CAS 886954-84-3](/s/DZPDEMIHOGVDCH-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886954-84-3C17H16FN3O4S2
![N-(4-Acetylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide chemical structure, C17H14FN3O4S2, CAS 886955-88-0](/s/LWUFRDGULARTQW-UHFFFAOYSA-N.svg)
N-(4-Acetylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
CAS 886955-88-0C17H14FN3O4S2
![2-((1,1-Dioxido-4-propyl-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-fluorophenyl)acetamide chemical structure, C18H18FN3O3S2, CAS 933025-57-1](/s/CCZSIDHCTGPVGZ-UHFFFAOYSA-N.svg)
2-((1,1-Dioxido-4-propyl-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-fluorophenyl)acetamide
CAS 933025-57-1C18H18FN3O3S2
- 2-((4-Butyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(o-tolyl)acetamide893790-06-2C20H23N3O3S2
- 2-((4-Butyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-chlorophenyl)acetamide893790-08-4C19H20ClN3O3S2
- 2-((4-Butyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(5-chloro-2-methylphenyl)acetamide893790-14-2C20H22ClN3O3S2
- 2-((4-Butyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(2-chloro-4-methylphenyl)acetamide893790-16-4C20H22ClN3O3S2
- 2-((4-Butyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-chloro-2-methylphenyl)acetamide893790-22-2C20H22ClN3O3S2
- 2-[(4-Butyl-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]-N-(3-chloro-4-methylphenyl)acetamide893790-52-8C20H22ClN3O3S2
- 2-[(4-Butyl-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)thio]-N-(4-chlorophenyl)acetamide892360-29-1C19H20ClN3O3S2
- Ethyl 2-(2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamido)benzoate886955-79-9C18H16FN3O5S2
- Ethyl 2-(2-((1,1-dioxido-4-propyl-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamido)benzoate899725-66-7C21H23N3O5S2
- 2-((1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(o-tolyl)acetamide899976-06-8C16H15N3O3S2
- 2-((1,1-Dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(m-tolyl)acetamide896683-70-8C16H15N3O3S2
- N-(4-Butylphenyl)-2-[(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]acetamide886953-54-4C19H21N3O3S2
- N-(4-Butylphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide886953-59-9C19H20FN3O3S2
- N-(4-Bromophenyl)-2-((1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide886953-99-7C15H12BrN3O3S2
- N-(5-Chloro-2-methoxyphenyl)-2-((7-fluoro-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide886954-44-5C16H13ClFN3O4S2
- 2-[(1,1-Dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]-N-(2-ethoxyphenyl)acetamide886954-69-4C17H17N3O4S2
- 2-[(7-Fluoro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide886955-39-1C16H11F4N3O3S2
- N-(4-Acetamidophenyl)-2-((1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide899966-05-3C17H16N4O4S2
- 2-[(1,1-Dioxo-4-propyl-4H-1lambda6,2,4-benzothiadiazin-3-yl)sulfanyl]-N-(2-methoxyphenyl)acetamide899977-83-4C19H21N3O4S2
- N-(2,5-Dimethoxyphenyl)-2-((1,1-dioxido-4-propyl-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide899725-62-3C20H23N3O5S2
- 2-((4-Ethyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(3-methoxyphenyl)acetamide941950-71-6C18H19N3O4S2
- N-(3,4-Dimethoxyphenyl)-2-((4-ethyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide941950-75-0C19H21N3O5S2
- 2-((4-Ethyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)-N-(4-ethylphenyl)acetamide941899-63-4C19H21N3O3S2
- N-(3-Chloro-4-methoxyphenyl)-2-((4-ethyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide941950-67-0C18H18ClN3O4S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CSc1nc(=O)n2ccccc2n1)Nc1ccccc115 chemicals
O=C(CCNc1ccccc1)c1ccc2ccccc2c115 chemicals
O=C(COc1ccccc1)Nc1ccc2c(c1)OCCO215 chemicals![Scaffold O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc1ccccc1](/scaffold/KDRIURZVJMYZNJ-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc1ccccc113 chemicals
O=C(CCc1ccccc1)Nc1ccc2ccccc2c113 chemicals![Scaffold O=C(NCCc1cc2ccccc2[nH]c1=O)c1ccccc1](/scaffold/RLWQKKJAXJDFAZ-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1cc2ccccc2[nH]c1=O)c1ccccc112 chemicals
O=C(CCN1CCc2ccccc2C1)Nc1ccccc110 chemicals
O=C(CSc1ccc2ccccc2n1)Nc1ccccc18 chemicals
O=C(CCn1cnc2ccccc2c1=O)Nc1ccccc18 chemicals
O=C(NCCc1ccccc1)c1cc2ccccc2oc1=O7 chemicals
O=C(NCCc1ccccc1)c1cc(=O)c2ccccc2o17 chemicals
O=C(CC1Sc2ccccc2NC1=O)NCc1ccccc17 chemicals