Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 18 atoms

24 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 24
With full pages: 6

Scaffold SMILES

O=c1[nH]c(SCc2ccccc2)nc2c1SCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1[nH]c(SCc2ccccc2)nc2c1SCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-[(4-Bromophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C14H13BrN2OS2, CAS 869076-13-1

2-[(4-Bromophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-13-1C₁₄H₁₃BrN₂OS₂

3-Methyl-2-[(2-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H16N2OS2, CAS 869076-14-2

3-Methyl-2-[(2-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-14-2C₁₅H₁₆N₂OS₂

2-[(4-Chlorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C14H13ClN2OS2, CAS 869076-15-3

2-[(4-Chlorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-15-3C₁₄H₁₃ClN₂OS₂

3-Methyl-2-[(4-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C14H13N3O3S2, CAS 869076-16-4

3-Methyl-2-[(4-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-16-4C₁₄H₁₃N₃O₃S₂

2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C14H12ClFN2OS2, CAS 869076-17-5

2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-17-5C₁₄H₁₂ClFN₂OS₂

3-Methyl-2-[(3-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H16N2OS2, CAS 869076-18-6

3-Methyl-2-[(3-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-18-6C₁₅H₁₆N₂OS₂

2-[(2-Chlorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C14H13ClN2OS2, CAS 869076-19-7

2-[(2-Chlorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-19-7C₁₄H₁₃ClN₂OS₂

2-[(2,5-Dimethylphenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C16H18N2OS2, CAS 869076-20-0

2-[(2,5-Dimethylphenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 869076-20-0C₁₆H₁₈N₂OS₂

2-[(3-Chlorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C14H13ClN2OS2, CAS 887225-36-7

2-[(3-Chlorophenyl)methylsulfanyl]-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 887225-36-7C₁₄H₁₃ClN₂OS₂

3-Methyl-2-[(3-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C14H13N3O3S2, CAS 893362-69-1

3-Methyl-2-[(3-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893362-69-1C₁₄H₁₃N₃O₃S₂

2-Benzylsulfanyl-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H16N2OS2, CAS 893368-42-8

2-Benzylsulfanyl-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893368-42-8C₁₅H₁₆N₂OS₂

3-Ethyl-2-[(3-fluorophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H15FN2OS2, CAS 887225-37-8

3-Ethyl-2-[(3-fluorophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 887225-37-8C₁₅H₁₅FN₂OS₂

3-Ethyl-2-[(4-fluorophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H15FN2OS2, CAS 887225-38-9

3-Ethyl-2-[(4-fluorophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 887225-38-9C₁₅H₁₅FN₂OS₂

2-[(4-Chlorophenyl)methylsulfanyl]-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H15ClN2OS2, CAS 887225-39-0

2-[(4-Chlorophenyl)methylsulfanyl]-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 887225-39-0C₁₅H₁₅ClN₂OS₂

3-Ethyl-2-[(4-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H15N3O3S2, CAS 893368-64-4

3-Ethyl-2-[(4-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893368-64-4C₁₅H₁₅N₃O₃S₂

2-((2-Chloro-6-fluorobenzyl)thio)-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C15H14ClFN2OS2, CAS 887225-40-3

2-((2-Chloro-6-fluorobenzyl)thio)-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one

CAS 887225-40-3C₁₅H₁₄ClFN₂OS₂

3-Ethyl-2-[(3-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C16H18N2OS2, CAS 893368-72-4

3-Ethyl-2-[(3-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893368-72-4C₁₆H₁₈N₂OS₂

2-((2,5-Dimethylbenzyl)thio)-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C17H20N2OS2, CAS 893368-88-2

2-((2,5-Dimethylbenzyl)thio)-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one

CAS 893368-88-2C₁₇H₂₀N₂OS₂

2-[(3-Chlorophenyl)methylsulfanyl]-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H15ClN2OS2, CAS 887225-41-4

2-[(3-Chlorophenyl)methylsulfanyl]-3-ethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 887225-41-4C₁₅H₁₅ClN₂OS₂

3-Ethyl-2-[(3-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C15H15N3O3S2, CAS 893369-58-9

3-Ethyl-2-[(3-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893369-58-9C₁₅H₁₅N₃O₃S₂

3-(2-Methoxyethyl)-2-[(4-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C16H17N3O4S2, CAS 893376-08-4

3-(2-Methoxyethyl)-2-[(4-nitrophenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893376-08-4C₁₆H₁₇N₃O₄S₂

2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-3-(2-methoxyethyl)-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C16H16ClFN2O2S2, CAS 893376-15-3

2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-3-(2-methoxyethyl)-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893376-15-3C₁₆H₁₆ClFN₂O₂S₂

3-(2-Methoxyethyl)-2-[(3-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C17H20N2O2S2, CAS 893376-23-3

3-(2-Methoxyethyl)-2-[(3-methylphenyl)methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893376-23-3C₁₇H₂₀N₂O₂S₂

3-(2-Methoxyethyl)-2-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C17H17F3N2O2S2, CAS 893376-54-0

3-(2-Methoxyethyl)-2-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-6,7-dihydrothieno[3,2-d]pyrimidin-4-one

CAS 893376-54-0C₁₇H₁₇F₃N₂O₂S₂