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Murcko scaffold

2-(Pyrrolidin-2-yl)-1,3-thiazole scaffold

77 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
77
With full pages
5
Scaffold SMILES

c1csc(C2CCCN2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-2-yl)-1,3-thiazole page
Murcko scaffold c1csc(C2CCCN2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

2-(1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)thiazole-4-carboxylic acid chemical structure, C13H18N2O4S, CAS 1824349-18-9
2-(1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)thiazole-4-carboxylic acid
CAS 1824349-18-9C13H18N2O4S
Ethyl 2-(pyrrolidin-2-yl)-1,3-thiazole-4-carboxylate chemical structure, C10H14N2O2S, CAS 1190775-48-4
Ethyl 2-(pyrrolidin-2-yl)-1,3-thiazole-4-carboxylate
CAS 1190775-48-4C10H14N2O2S
2-(Pyrrolidin-2-yl)-1,3-thiazole chemical structure, C7H10N2S, CAS 524674-17-7
2-(Pyrrolidin-2-yl)-1,3-thiazole
CAS 524674-17-7C7H10N2S
(S)-2-(Pyrrolidin-2-yl)thiazole chemical structure, C7H10N2S, CAS 1219909-41-7
(S)-2-(Pyrrolidin-2-yl)thiazole
CAS 1219909-41-7C7H10N2S
(r)-2-(Pyrrolidin-2-yl)thiazole chemical structure, C7H10N2S, CAS 1228558-20-0
(r)-2-(Pyrrolidin-2-yl)thiazole
CAS 1228558-20-0C7H10N2S
2-((S)-1-tert-Butoxycarbonyl-pyrrolidin-2-yl)-thiazole-4-carboxylic acid ethyl ester chemical structure, C15H22N2O4S, CAS 212009-06-8
2-((S)-1-tert-Butoxycarbonyl-pyrrolidin-2-yl)-thiazole-4-carboxylic acid ethyl ester
CAS 212009-06-8C15H22N2O4S
Antibiotic-5d chemical structure, C13H18N2O4S, CAS 251349-54-9
Antibiotic-5d
CAS 251349-54-9C13H18N2O4S
Apramide G chemical structure, C44H73N7O6S, CAS 289726-40-5
Apramide G
CAS 289726-40-5C44H73N7O6S
Dysideaproline B chemical structure, C20H29Cl4N3O2S, CAS 364321-05-1
Dysideaproline B
CAS 364321-05-1C20H29Cl4N3O2S
Dysideaproline A chemical structure, C19H27Cl4N3O2S, CAS 364321-04-0
Dysideaproline A
CAS 364321-04-0C19H27Cl4N3O2S
Dysideaproline C chemical structure, C18H25Cl4N3O2S, CAS 364321-06-2
Dysideaproline C
CAS 364321-06-2C18H25Cl4N3O2S
Dysideaproline F chemical structure, C19H28Cl3N3O2S, CAS 364321-09-5
Dysideaproline F
CAS 364321-09-5C19H28Cl3N3O2S
Dysideaproline E chemical structure, C19H29Cl2N3O2S, CAS 364321-08-4
Dysideaproline E
CAS 364321-08-4C19H29Cl2N3O2S
Dysideaproline D chemical structure, C19H29Cl2N3O2S, CAS 364321-07-3
Dysideaproline D
CAS 364321-07-3C19H29Cl2N3O2S
Methyl 2-(1-Methylpyrrolidin-2-yl)thiazole-4-carboxylate chemical structure, C10H14N2O2S, CAS 2105662-76-6
Methyl 2-(1-Methylpyrrolidin-2-yl)thiazole-4-carboxylate
CAS 2105662-76-6C10H14N2O2S
4-Methyl-2-(pyrrolidin-2-yl)-1,3-thiazole chemical structure, C8H12N2S, CAS 933682-46-3
4-Methyl-2-(pyrrolidin-2-yl)-1,3-thiazole
CAS 933682-46-3C8H12N2S
4,5-Dimethyl-2-(pyrrolidin-2-yl)-1,3-thiazole chemical structure, C9H14N2S, CAS 1017184-04-1
4,5-Dimethyl-2-(pyrrolidin-2-yl)-1,3-thiazole
CAS 1017184-04-1C9H14N2S
(S)-4,5-Dimethyl-2-(pyrrolidin-2-yl)thiazole chemical structure, C9H14N2S, CAS 479067-48-6
(S)-4,5-Dimethyl-2-(pyrrolidin-2-yl)thiazole
CAS 479067-48-6C9H14N2S
4-(tert-Butyl) 2-methyl (2R,5S)-2-isobutyl-5-(1,3-thiazol-2-yl)tetrahydro-1H-pyrrole-2,4-dicarboxyla chemical structure, C18H28N2O4S, CAS 1217691-33-2
4-(tert-Butyl) 2-methyl (2R,5S)-2-isobutyl-5-(1,3-thiazol-2-yl)tetrahydro-1H-pyrrole-2,4-dicarboxyla
CAS 1217691-33-2C18H28N2O4S
(r)-4,5-Dimethyl-2-(pyrrolidin-2-yl)thiazole chemical structure, C9H14N2S, CAS 1821837-31-3
(r)-4,5-Dimethyl-2-(pyrrolidin-2-yl)thiazole
CAS 1821837-31-3C9H14N2S
(R)-Ethyl 2-(pyrrolidin-2-yl)thiazole-4-carboxylate hydrochloride chemical structure, C10H15ClN2O2S, CAS 1217653-08-1
(R)-Ethyl 2-(pyrrolidin-2-yl)thiazole-4-carboxylate hydrochloride
CAS 1217653-08-1C10H15ClN2O2S
Ethyl 2-((R)-pyrrolidin-2-yl)thiazole-4-carboxylate hydrochloride chemical structure, C10H15ClN2O2S, CAS 251349-56-1
Ethyl 2-((R)-pyrrolidin-2-yl)thiazole-4-carboxylate hydrochloride
CAS 251349-56-1C10H15ClN2O2S
4-Methyl-2-pyrrolidin-2-yl-thiazole dihydrochloride chemical structure, C8H14Cl2N2S, CAS 1185302-93-5
4-Methyl-2-pyrrolidin-2-yl-thiazole dihydrochloride
CAS 1185302-93-5C8H14Cl2N2S
(S)-2-(Pyrrolidin-2-yl)thiazole hydrobromide chemical structure, C7H11BrN2S, CAS 1219833-11-0
(S)-2-(Pyrrolidin-2-yl)thiazole hydrobromide
CAS 1219833-11-0C7H11BrN2S