CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

96 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
96
With full pages
5
Scaffold SMILES

O=C(C=Cc1ccc2c(c1)OCO2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc2c(c1)OCO2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 96 chemicals

(E)-N-(3-Acetylphenyl)-3-(1,3-benzodioxol-5-yl)prop-2-enamide chemical structure, C18H15NO4, CAS 300825-72-3
(E)-N-(3-Acetylphenyl)-3-(1,3-benzodioxol-5-yl)prop-2-enamide
CAS 300825-72-3C18H15NO4
3-(1,3-Benzodioxol-5-yl)-N-(4-fluorophenyl)acrylamide chemical structure, C16H12FNO3, CAS 298215-60-8
3-(1,3-Benzodioxol-5-yl)-N-(4-fluorophenyl)acrylamide
CAS 298215-60-8C16H12FNO3
3-(1,3-Benzodioxol-5-yl)-N-(3-chloro-4-methylphenyl)acrylamide chemical structure, C17H14ClNO3, CAS 298215-59-5
3-(1,3-Benzodioxol-5-yl)-N-(3-chloro-4-methylphenyl)acrylamide
CAS 298215-59-5C17H14ClNO3
3-(1,3-Benzodioxol-5-yl)-N-(2,4-dimethoxyphenyl)prop-2-enamide chemical structure, C18H17NO5, CAS 298215-63-1
3-(1,3-Benzodioxol-5-yl)-N-(2,4-dimethoxyphenyl)prop-2-enamide
CAS 298215-63-1C18H17NO5
3-(1,3-Benzodioxol-5-yl)-N-(2,4-dimethoxyphenyl)acrylamide chemical structure, C18H17NO5, CAS 5703-74-2
3-(1,3-Benzodioxol-5-yl)-N-(2,4-dimethoxyphenyl)acrylamide
CAS 5703-74-2C18H17NO5
3-(1,3-Benzodioxol-5-yl)-N-(4-(tert-butyl)phenyl)acrylamide chemical structure, C20H21NO3, CAS 850496-14-9
3-(1,3-Benzodioxol-5-yl)-N-(4-(tert-butyl)phenyl)acrylamide
CAS 850496-14-9C20H21NO3
3-Benzo[1,3]dioxol-5-yl-N-o-tolyl-acrylamide chemical structure, C17H15NO3, CAS 5360-28-1
3-Benzo[1,3]dioxol-5-yl-N-o-tolyl-acrylamide
CAS 5360-28-1C17H15NO3
3-(1,3-Benzodioxol-5-yl)-N-(4-methylphenyl)acrylamide chemical structure, C17H15NO3, CAS 74957-51-0
3-(1,3-Benzodioxol-5-yl)-N-(4-methylphenyl)acrylamide
CAS 74957-51-0C17H15NO3
3-(1,3-Benzodioxol-5-yl)-N-(3,4-dimethylphenyl)acrylamide chemical structure, C18H17NO3, CAS 300825-67-6
3-(1,3-Benzodioxol-5-yl)-N-(3,4-dimethylphenyl)acrylamide
CAS 300825-67-6C18H17NO3
N-(4-Acetyl-phenyl)-3-benzo[1,3]dioxol-5-yl-acrylamide chemical structure, C18H15NO4, CAS 5362-44-7
N-(4-Acetyl-phenyl)-3-benzo[1,3]dioxol-5-yl-acrylamide
CAS 5362-44-7C18H15NO4
3-(1,3-Benzodioxol-5-yl)-N-(2-methoxy-5-methylphenyl)acrylamide chemical structure, C18H17NO4, CAS 297149-88-3
3-(1,3-Benzodioxol-5-yl)-N-(2-methoxy-5-methylphenyl)acrylamide
CAS 297149-88-3C18H17NO4
(E)-3-(1,3-Benzodioxol-5-yl)-N-(4-sulfamoylphenyl)prop-2-enamide chemical structure, C16H14N2O5S, CAS 349578-38-7
(E)-3-(1,3-Benzodioxol-5-yl)-N-(4-sulfamoylphenyl)prop-2-enamide
CAS 349578-38-7C16H14N2O5S
(E)-N-(4-Acetamidophenyl)-3-(1,3-benzodioxol-5-yl)prop-2-enamide chemical structure, C18H16N2O4, CAS 86181-72-8
(E)-N-(4-Acetamidophenyl)-3-(1,3-benzodioxol-5-yl)prop-2-enamide
CAS 86181-72-8C18H16N2O4
2-[[(E)-3-(1,3-Benzodioxol-5-yl)prop-2-enoyl]amino]benzamide chemical structure, C17H14N2O4, CAS 188544-25-4
2-[[(E)-3-(1,3-Benzodioxol-5-yl)prop-2-enoyl]amino]benzamide
CAS 188544-25-4C17H14N2O4
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2,6-dichlorophenyl)prop-2-enamide chemical structure, C16H11Cl2NO3, CAS 545347-51-1
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2,6-dichlorophenyl)prop-2-enamide
CAS 545347-51-1C16H11Cl2NO3
(E)-3-(1,3-Benzodioxol-5-yl)-N-(3-ethylphenyl)prop-2-enamide chemical structure, C18H17NO3, CAS 522641-28-7
(E)-3-(1,3-Benzodioxol-5-yl)-N-(3-ethylphenyl)prop-2-enamide
CAS 522641-28-7C18H17NO3
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2-methyl-6-propan-2-ylphenyl)prop-2-enamide chemical structure, C20H21NO3, CAS 547696-77-5
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2-methyl-6-propan-2-ylphenyl)prop-2-enamide
CAS 547696-77-5C20H21NO3
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2-methoxy-5-nitrophenyl)prop-2-enamide chemical structure, C17H14N2O6, CAS 349427-65-2
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2-methoxy-5-nitrophenyl)prop-2-enamide
CAS 349427-65-2C17H14N2O6
3-(1,3-Benzodioxol-5-yl)-N-(2-methyl-5-nitrophenyl)acrylamide chemical structure, C17H14N2O5, CAS 6115-44-2
3-(1,3-Benzodioxol-5-yl)-N-(2-methyl-5-nitrophenyl)acrylamide
CAS 6115-44-2C17H14N2O5
(E)-3-(1,3-Benzodioxol-5-yl)-N-ethyl-N-(2-methylphenyl)prop-2-enamide chemical structure, C19H19NO3, CAS 346715-48-8
(E)-3-(1,3-Benzodioxol-5-yl)-N-ethyl-N-(2-methylphenyl)prop-2-enamide
CAS 346715-48-8C19H19NO3
2-{[(2E)-3-(1,3-Benzodioxol-5-yl)prop-2-enoyl]amino}benzoic acid chemical structure, C17H13NO5, CAS 1010115-96-4
2-{[(2E)-3-(1,3-Benzodioxol-5-yl)prop-2-enoyl]amino}benzoic acid
CAS 1010115-96-4C17H13NO5
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2-fluoro-5-nitrophenyl)prop-2-enamide chemical structure, C16H11FN2O5, CAS 349578-14-9
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2-fluoro-5-nitrophenyl)prop-2-enamide
CAS 349578-14-9C16H11FN2O5
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2,3-dichlorophenyl)prop-2-enamide chemical structure, C16H11Cl2NO3, CAS 349578-34-3
(E)-3-(1,3-Benzodioxol-5-yl)-N-(2,3-dichlorophenyl)prop-2-enamide
CAS 349578-34-3C16H11Cl2NO3
(E)-N-(3-Acetamidophenyl)-3-(1,3-benzodioxol-5-yl)prop-2-enamide chemical structure, C18H16N2O4, CAS 349578-13-8
(E)-N-(3-Acetamidophenyl)-3-(1,3-benzodioxol-5-yl)prop-2-enamide
CAS 349578-13-8C18H16N2O4