Murcko scaffold
Ring system with 2 rings and 16 atoms
235 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 235
- With full pages
- 6
Scaffold SMILES
O=C(NC1CCCC1)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 235 chemicals
1-(((Phenylmethoxy)carbonyl)amino)cyclopentanecarboxylic acid
CAS 17191-44-5C14H17NO4
(1R,2S)-2-(Phenylmethoxycarbonylamino)cyclopentane-1-carboxylic acid
CAS 625095-27-4C14H17NO4
![(1S,2S)-2-{[(Benzyloxy)carbonyl]amino}cyclopentane-1-carboxylic acid chemical structure, C14H17NO4, CAS 957229-99-1](/s/NVZVMVSTQZDUJQ-RYUDHWBXSA-N.svg)
(1S,2S)-2-{[(Benzyloxy)carbonyl]amino}cyclopentane-1-carboxylic acid
CAS 957229-99-1C14H17NO4
![Benzyl N-[(1R,2R)-2-hydroxycyclopentyl]carbamate chemical structure, C13H17NO3, CAS 144989-61-7](/s/NPXGDPYTWXXJKU-VXGBXAGGSA-N.svg)
Benzyl N-[(1R,2R)-2-hydroxycyclopentyl]carbamate
CAS 144989-61-7C13H17NO3
![Benzyl N-[(1R,2S)-2-hydroxycyclopentyl]carbamate chemical structure, C13H17NO3, CAS 221152-96-1](/s/NPXGDPYTWXXJKU-NEPJUHHUSA-N.svg)
Benzyl N-[(1R,2S)-2-hydroxycyclopentyl]carbamate
CAS 221152-96-1C13H17NO3
![Benzyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate chemical structure, C13H17NO3, CAS 198422-71-8](/s/NPXGDPYTWXXJKU-RYUDHWBXSA-N.svg)
Benzyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate
CAS 198422-71-8C13H17NO3
(1-Hydroxymethyl-cyclopentyl)-carbamic acid benzyl ester
CAS 676560-72-8C14H19NO3
Benzyl (2-hydroxycyclopentyl)carbamate
CAS 221152-90-5C13H17NO3
![rac-(1R,2S)-2-{[(Benzyloxy)carbonyl]amino}cyclopentane-1-sulfonic acid chemical structure, C13H17NO5S, CAS 678166-72-8](/s/VXZHLBUPKLMYCF-NWDGAFQWSA-N.svg)
rac-(1R,2S)-2-{[(Benzyloxy)carbonyl]amino}cyclopentane-1-sulfonic acid
CAS 678166-72-8C13H17NO5S
amino}acetic acid chemical structure, C15H19NO4, CAS 135836-35-0](/s/ZYZUPUCKSAOCNX-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl](cyclopentyl)amino}acetic acid
CAS 135836-35-0C15H19NO4
2-Benzyloxycarbonylamino-cyclopentanecarboxylic acid
CAS 778598-29-1C14H17NO4
![rac-(1R,2R)-2-{[(Benzyloxy)carbonyl]amino}cyclopentane-1-carboxylic acid chemical structure, C14H17NO4, CAS 61935-50-0](/s/NVZVMVSTQZDUJQ-VXGBXAGGSA-N.svg)
rac-(1R,2R)-2-{[(Benzyloxy)carbonyl]amino}cyclopentane-1-carboxylic acid
CAS 61935-50-0C14H17NO4
(1S,2R)-2-(Benzyloxycarbonylamino)cyclopentanecarboxylic acid
CAS 61935-49-7C14H17NO4
amino}cyclopentane-1-carboxylic acid chemical structure, C15H19NO4, CAS 287210-97-3](/s/IHAJBHBRYYRMOK-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl](methyl)amino}cyclopentane-1-carboxylic acid
CAS 287210-97-3C15H19NO4
![Benzyl N-[(3R,4S)-3,4-dihydroxycyclopentyl]carbamate chemical structure, C13H17NO4, CAS 193751-45-0](/s/TYEMNNUCROCIQN-YOGCLGLASA-N.svg)
Benzyl N-[(3R,4S)-3,4-dihydroxycyclopentyl]carbamate
CAS 193751-45-0C13H17NO4
![rac-(1R,2S,3R,4S)-4-{[(Benzyloxy)carbonyl]amino}-2,3-dihydroxycyclopentane-1-carboxylic acid chemical structure, C14H17NO6, CAS 145451-85-0](/s/VKXZVMXORUAAHZ-QCNOEVLYSA-N.svg)
rac-(1R,2S,3R,4S)-4-{[(Benzyloxy)carbonyl]amino}-2,3-dihydroxycyclopentane-1-carboxylic acid
CAS 145451-85-0C14H17NO6
![rac-Methyl (1R,2S,3R,4S)-4-{[(benzyloxy)carbonyl]amino}-2,3-dihydroxycyclopentane-1-carboxylate chemical structure, C15H19NO6, CAS 958652-90-9](/s/DJNAYZHWHPVCEO-MROQNXINSA-N.svg)
rac-Methyl (1R,2S,3R,4S)-4-{[(benzyloxy)carbonyl]amino}-2,3-dihydroxycyclopentane-1-carboxylate
CAS 958652-90-9C15H19NO6
![Benzyl N-[(1R,3S)-3-fluorocyclopentyl]carbamate chemical structure, C13H16FNO2, CAS 1932288-21-5](/s/NDVBOSIQTJVVNB-NWDGAFQWSA-N.svg)
Benzyl N-[(1R,3S)-3-fluorocyclopentyl]carbamate
CAS 1932288-21-5C13H16FNO2
Methyl 3-hydroxy-1-(phenylmethoxycarbonylamino)cyclopentane-1-carboxylate
CAS 1260638-72-9C15H19NO5
![Benzyl N-[3-hydroxy-1-(hydroxymethyl)cyclopentyl]carbamate chemical structure, C14H19NO4, CAS 1260637-45-3](/s/YCASJRROSDDCHH-UHFFFAOYSA-N.svg)
Benzyl N-[3-hydroxy-1-(hydroxymethyl)cyclopentyl]carbamate
CAS 1260637-45-3C14H19NO4
Benzyl (3-hydroxycyclopentyl)carbamate
CAS 939426-84-3C13H17NO3
Methyl 2-(phenylmethoxycarbonylamino)cyclopentane-1-carboxylate
CAS 1260654-77-0C15H19NO4
Benzyl (trans-3-hydroxycyclopentyl)carbamate
CAS 1932370-17-6C13H17NO3
![2-{[(Benzyloxy)carbonyl]amino}-4-hydroxycyclopentane-1-carboxylic acid chemical structure, C14H17NO5, CAS 2580242-45-9](/s/STKZBYIWMVOUHU-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-4-hydroxycyclopentane-1-carboxylic acid
CAS 2580242-45-9C14H17NO5
- 3-{[(Benzyloxy)carbonyl]amino}-1-methylcyclopentane-1-carboxylic acid2580183-66-8C15H19NO4
- Benzyl (3-aminocyclopentyl)carbamate1229624-63-8C13H18N2O2
- Benzyl ((1R,3S)-3-aminocyclopentyl)carbamate1380486-07-6C13H18N2O2
- Carbamic acid, [3-(formyloxy)cyclopentyl]-, phenylmethyl ester, trans-124555-32-4C14H17NO4
- cis-Benzyl (3-hydroxycyclopentyl)carbamate124555-31-3C13H17NO3
- rac-Benzyl N-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]carbamate1332385-88-2C14H19NO5
- trans-Benzyl 3-hydroxycyclopentylcarbamate167298-57-9C13H17NO3
- Benzyl tert-butyl ((1S,3S)-cyclopentane-1,3-diyl)dicarbamate1932086-33-3C18H26N2O4
- Benzyl N-cyclopentyl-N-(2-hydroxyethyl)carbamate1303504-05-3C15H21NO3
- 1-{[(Benzyloxy)carbonyl]amino}-3-methylcyclopentane-1-carboxylic acid1496758-47-4C15H19NO4
- 2-(1-{[(Benzyloxy)carbonyl]amino}cyclopentyl)acetic acid1339747-03-3C15H19NO4
- 1-{[(Benzyloxy)carbonyl]amino}-2-methylcyclopentane-1-carboxylic acid1495525-04-6C15H19NO4
- 3-(((Benzyloxy)carbonyl)amino)cyclopentane-1-carboxylic acid1427475-13-5C14H17NO4
- Benzyl N-[1-(aminomethyl)cyclopentyl]carbamate1352999-72-4C14H20N2O2
- Benzyl N-(1-cyanocyclopentyl)carbamate1352999-40-6C14H16N2O2
- Benzyl N-[(1R,3S)-3-(hydroxymethyl)cyclopentyl]carbamate1380486-16-7C14H19NO3
- (1S,3R)-3-{[(Benzyloxy)carbonyl]amino}cyclopentane-1-carboxylic acid1380486-21-4C14H17NO4
- Benzyl N-[(1R,3S)-3-aminocyclopentyl]carbamate oxalate1418119-71-7C15H20N2O6
- Methyl (1S,3R)-3-{[(benzyloxy)carbonyl]amino}cyclopentane-1-carboxylate1421769-37-0C15H19NO4
- (1-Methoxymethyl-cyclopentyl)-carbamic acid benzyl ester676560-73-9C15H21NO3
- Benzyl 3,3-difluorocyclopentylcarbamate939385-02-1C13H15F2NO2
- 1 suppliers(1S,3R)-1-(Boc-amino)-3-(Cbz-amino)cyclopentane1315495-87-4C18H26N2O4
- Benzyl N-(3-hydroxy-2,2-dimethylcyclopentyl)carbamate2680858-38-0C15H21NO3
- Benzyl N-(2-hydroxy-2-methylcyclopentyl)carbamate2680748-11-0C14H19NO3
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nnc[nH]1)Nc1ccccc1](/scaffold/VJBDIQRNSVRUDP-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnc[nH]1)Nc1ccccc165 chemicals
O=C(COc1ccccc1)Nc1nccs143 chemicals
O=C(CCc1ccco1)Nc1ccccc134 chemicals
O=C(CSc1nncs1)Nc1ccccc134 chemicals![Scaffold O=C(NN=Cc1ccccc1)c1cc[nH]n1](/scaffold/UEBQXDJERRSAMF-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1ccccc1)c1cc[nH]n129 chemicals
O=C(CCc1ccccc1)Nc1nncs125 chemicals
S=C(NCc1ccco1)Nc1ccccc124 chemicals![Scaffold O=C(CSc1nnn[nH]1)Nc1ccccc1](/scaffold/FDRBWKCIVMSABC-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnn[nH]1)Nc1ccccc122 chemicals![Scaffold O=C(CSc1ncc[nH]1)Nc1ccccc1](/scaffold/OMOYRSCPUXAYDW-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncc[nH]1)Nc1ccccc121 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccco121 chemicals
O=C(CCN1CCCC1)Nc1ccccc120 chemicals
O=C(NN=Cc1ccco1)c1ccccc119 chemicals