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Murcko scaffold

Ring system with 3 rings and 20 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(NC1CCCNC1)c1ccc(-c2ccccc2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCCNC1)c1ccc(-c2ccccc2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Azd7762 chemical structure, C17H19FN4O2S, CAS 860352-01-8
Azd7762
CAS 860352-01-8C17H19FN4O2S
5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide chemical structure, C17H19FN4O2S, CAS 1184916-21-9
5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
CAS 1184916-21-9C17H19FN4O2S
tert-Butyl (3S)-3-({[3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-2-thienyl]-carbonyl}amino)piperidine-1-carboxylate chemical structure, C22H27FN4O4S, CAS 860354-61-6
tert-Butyl (3S)-3-({[3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-2-thienyl]-carbonyl}amino)piperidine-1-carboxylate
CAS 860354-61-6C22H27FN4O4S
(S)-tert-Butyl 3-(3-amino-5-(3-fluorophenyl)thiophene-2-carboxamido)piperidine-1-carboxylate chemical structure, C21H26FN3O3S, CAS 1192875-04-9
(S)-tert-Butyl 3-(3-amino-5-(3-fluorophenyl)thiophene-2-carboxamido)piperidine-1-carboxylate
CAS 1192875-04-9C21H26FN3O3S
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide hydrochloride chemical structure, C17H20ClFN4O2S, CAS 1246094-78-9
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide hydrochloride
CAS 1246094-78-9C17H20ClFN4O2S
(S)-5-(4-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide chemical structure, C17H19FN4O2S, CAS 860352-99-4
(S)-5-(4-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
CAS 860352-99-4C17H19FN4O2S
tert-Butyl (S)-3-(5-(3-fluorophenyl)-3-(3-(2,2,2-trichloroacetyl)ureido)thiophene-2-carboxamido)piperidine-1-carboxylate chemical structure, C24H26Cl3FN4O5S, CAS 1192875-05-0
tert-Butyl (S)-3-(5-(3-fluorophenyl)-3-(3-(2,2,2-trichloroacetyl)ureido)thiophene-2-carboxamido)piperidine-1-carboxylate
CAS 1192875-05-0C24H26Cl3FN4O5S
5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide hydrochloride chemical structure, C17H20ClFN4O2S, CAS 2089300-74-1
5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide hydrochloride
CAS 2089300-74-1C17H20ClFN4O2S