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Murcko scaffold

Ring system with 2 rings and 10 atoms

175 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
175
With full pages
30
Scaffold SMILES

c1ncc(B2OCCO2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ncc(B2OCCO2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 175 of 175 chemicals

4-Bromo-2-(n-propyl)thiazole-5-boronic acid pinacol ester chemical structure, C12H19BBrNO2S, CAS 2223043-59-0
4-Bromo-2-(n-propyl)thiazole-5-boronic acid pinacol ester
CAS 2223043-59-0C12H19BBrNO2S
4-(n-Propyl)thiazole-5-boronic acid pinacol ester chemical structure, C12H20BNO2S, CAS 2223040-72-8
4-(n-Propyl)thiazole-5-boronic acid pinacol ester
CAS 2223040-72-8C12H20BNO2S
4-Ethyl-2-(dimethylamino)thiazole-5-boronic acid pinacol ester chemical structure, C13H23BN2O2S, CAS 2223048-21-1
4-Ethyl-2-(dimethylamino)thiazole-5-boronic acid pinacol ester
CAS 2223048-21-1C13H23BN2O2S
4-Methyl-2-(iso-propoxy)thiazole-5-boronic acid pinacol ester chemical structure, C13H22BNO3S, CAS 2223011-51-4
4-Methyl-2-(iso-propoxy)thiazole-5-boronic acid pinacol ester
CAS 2223011-51-4C13H22BNO3S
4-(iso-Propyl)-2-(dimethylamino)thiazole-5-boronic acid pinacol ester chemical structure, C14H25BN2O2S, CAS 2223037-96-3
4-(iso-Propyl)-2-(dimethylamino)thiazole-5-boronic acid pinacol ester
CAS 2223037-96-3C14H25BN2O2S
4-(iso-Propyl)-2-bromothiazole-5-boronic acid pinacol ester chemical structure, C12H19BBrNO2S, CAS 2223035-83-2
4-(iso-Propyl)-2-bromothiazole-5-boronic acid pinacol ester
CAS 2223035-83-2C12H19BBrNO2S
4-Bromo-2-(dimethylamino)thiazole-5-boronic acid pinacol ester chemical structure, C11H18BBrN2O2S, CAS 2223029-37-4
4-Bromo-2-(dimethylamino)thiazole-5-boronic acid pinacol ester
CAS 2223029-37-4C11H18BBrN2O2S
4-Bromo-2-(methylethylamino)thiazole-5-boronic acid pinacol ester chemical structure, C12H20BBrN2O2S, CAS 2223038-92-2
4-Bromo-2-(methylethylamino)thiazole-5-boronic acid pinacol ester
CAS 2223038-92-2C12H20BBrN2O2S
4-Bromo-2-methoxythiazole-5-boronic acid pinacol ester chemical structure, C10H15BBrNO3S, CAS 2223048-13-1
4-Bromo-2-methoxythiazole-5-boronic acid pinacol ester
CAS 2223048-13-1C10H15BBrNO3S
4-Bromo-2-ethoxythiazole-5-boronic acid pinacol ester chemical structure, C11H17BBrNO3S, CAS 2223030-47-3
4-Bromo-2-ethoxythiazole-5-boronic acid pinacol ester
CAS 2223030-47-3C11H17BBrNO3S
4-Bromo-2-(iso-propoxy)thiazole-5-boronic acid pinacol ester chemical structure, C12H19BBrNO3S, CAS 2223038-70-6
4-Bromo-2-(iso-propoxy)thiazole-5-boronic acid pinacol ester
CAS 2223038-70-6C12H19BBrNO3S
4-Bromo-2-chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C9H12BBrClNO2S, CAS 2223030-04-2
4-Bromo-2-chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 2223030-04-2C9H12BBrClNO2S
2-Chloro-4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C10H15BClNO2S, CAS 2223038-84-2
2-Chloro-4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 2223038-84-2C10H15BClNO2S
2-Chloro-4-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C11H17BClNO2S, CAS 2223037-72-5
2-Chloro-4-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 2223037-72-5C11H17BClNO2S
2-(tert-Butyldimethylsilyl)-4-methylthiazole-5-boronic acid pinacol ester chemical structure, C16H30BNO2SSi, CAS 2377607-08-2
2-(tert-Butyldimethylsilyl)-4-methylthiazole-5-boronic acid pinacol ester
CAS 2377607-08-2C16H30BNO2SSi
(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)methanol chemical structure, C10H16BNO3S, CAS 1876408-21-7
(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)methanol
CAS 1876408-21-7C10H16BNO3S
4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)thiazole chemical structure, C11H15BF3NO2S, CAS 2256758-33-3
4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)thiazole
CAS 2256758-33-3C11H15BF3NO2S
2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C17H32BNO3SSi, CAS 2763334-08-1
2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2763334-08-1C17H32BNO3SSi
2-(Propan-2-yl-d7)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-4-d chemical structure, C12H20BNO2S, CAS 2241870-54-0
2-(Propan-2-yl-d7)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-4-d
CAS 2241870-54-0C12H20BNO2S
2-(Bromomethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C10H15BBrNO2S, CAS 2549181-45-3
2-(Bromomethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2549181-45-3C10H15BBrNO2S
1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl]ethanol chemical structure, C11H18BNO3S, CAS 2919688-31-4
1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl]ethanol
CAS 2919688-31-4C11H18BNO3S
N-{[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazol-2-yl]methyl}acetamide chemical structure, C12H19BN2O3S, CAS 2246576-33-8
N-{[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazol-2-yl]methyl}acetamide
CAS 2246576-33-8C12H19BN2O3S
Ethyl-d5 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-2-carboxylate-4-d chemical structure, C12H18BNO4S, CAS 2368221-99-0
Ethyl-d5 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-2-carboxylate-4-d
CAS 2368221-99-0C12H18BNO4S
Methyl-d3 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-2-carboxylate-4-d chemical structure, C11H16BNO4S, CAS 2368221-98-9
Methyl-d3 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-2-carboxylate-4-d
CAS 2368221-98-9C11H16BNO4S