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Murcko scaffold

[4-(Benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
13
With full pages
5
Scaffold SMILES

O=C(N1CCCCC1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the [4-(Benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone page
Murcko scaffold O=C(N1CCCCC1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Piperidin-1-yl-[4-(toluene-4-sulfonyl)-piperazin-1-yl]-methanone chemical structure, C17H25N3O3S, CAS 510734-56-2
Piperidin-1-yl-[4-(toluene-4-sulfonyl)-piperazin-1-yl]-methanone
CAS 510734-56-2C17H25N3O3S
[4-(2,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-piperidin-1-yl-methanone chemical structure, C18H27N3O3S, CAS 501104-62-7
[4-(2,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-piperidin-1-yl-methanone
CAS 501104-62-7C18H27N3O3S
4-[(4-Chlorophenyl)sulfonyl]piperazinyl piperidyl ketone chemical structure, C16H22ClN3O3S, CAS 708229-24-7
4-[(4-Chlorophenyl)sulfonyl]piperazinyl piperidyl ketone
CAS 708229-24-7C16H22ClN3O3S
4-[(4-Fluorophenyl)sulfonyl]piperazinyl piperidyl ketone chemical structure, C16H22FN3O3S, CAS 712345-24-9
4-[(4-Fluorophenyl)sulfonyl]piperazinyl piperidyl ketone
CAS 712345-24-9C16H22FN3O3S
4-[(3,4-Dimethylphenyl)sulfonyl]piperazinyl piperidyl ketone chemical structure, C18H27N3O3S, CAS 694473-68-2
4-[(3,4-Dimethylphenyl)sulfonyl]piperazinyl piperidyl ketone
CAS 694473-68-2C18H27N3O3S
(4-(Mesitylsulfonyl)piperazin-1-yl)(piperidin-1-yl)methanone chemical structure, C19H29N3O3S, CAS 708232-25-1
(4-(Mesitylsulfonyl)piperazin-1-yl)(piperidin-1-yl)methanone
CAS 708232-25-1C19H29N3O3S
[4-(Benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone chemical structure, C16H23N3O3S, CAS 510734-50-6
[4-(Benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone
CAS 510734-50-6C16H23N3O3S
4-[(3-Nitrophenyl)sulfonyl]piperazinyl piperidyl ketone chemical structure, C16H22N4O5S, CAS 694473-65-9
4-[(3-Nitrophenyl)sulfonyl]piperazinyl piperidyl ketone
CAS 694473-65-9C16H22N4O5S
(4-((3,4-Dimethylphenyl)sulfonyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C19H29N3O3S, CAS 890601-50-0
(4-((3,4-Dimethylphenyl)sulfonyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone
CAS 890601-50-0C19H29N3O3S
(4-(Mesitylsulfonyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C20H31N3O3S, CAS 890601-54-4
(4-(Mesitylsulfonyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone
CAS 890601-54-4C20H31N3O3S
N-(4-((4-(4-Methylpiperidine-1-carbonyl)piperazin-1-yl)sulfonyl)phenyl)acetamide chemical structure, C19H28N4O4S, CAS 890605-49-9
N-(4-((4-(4-Methylpiperidine-1-carbonyl)piperazin-1-yl)sulfonyl)phenyl)acetamide
CAS 890605-49-9C19H28N4O4S
(4-Methylpiperidin-1-yl)(4-(phenylsulfonyl)piperazin-1-yl)methanone chemical structure, C17H25N3O3S, CAS 890605-55-7
(4-Methylpiperidin-1-yl)(4-(phenylsulfonyl)piperazin-1-yl)methanone
CAS 890605-55-7C17H25N3O3S
4-[(4-Chlorophenyl)sulfonyl]piperazinyl 4-methylpiperidyl ketone chemical structure, C17H24ClN3O3S, CAS 890605-44-4
4-[(4-Chlorophenyl)sulfonyl]piperazinyl 4-methylpiperidyl ketone
CAS 890605-44-4C17H24ClN3O3S