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Murcko scaffold

3-Phenyl-1,2,4-thiadiazole scaffold

213 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
213
With full pages
42
Scaffold SMILES

c1ccc(-c2ncsn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-1,2,4-thiadiazole page
Murcko scaffold c1ccc(-c2ncsn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 213 chemicals

N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]butanamide chemical structure, C13H15N3O2S, CAS 898484-17-8
N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]butanamide
CAS 898484-17-8C13H15N3O2S
N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]propanamide chemical structure, C12H13N3O2S, CAS 679411-85-9
N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]propanamide
CAS 679411-85-9C12H13N3O2S
N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]pentanamide chemical structure, C14H17N3O2S, CAS 898484-25-8
N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]pentanamide
CAS 898484-25-8C14H17N3O2S
N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]-2-methylpropanamide chemical structure, C13H15N3O2S, CAS 898484-60-1
N-[3-(4-Methoxyphenyl)-1,2,4-thiadiazol-5-yl]-2-methylpropanamide
CAS 898484-60-1C13H15N3O2S
2-Ethyl-N-[3-(4-methoxyphenyl)-1,2,4-thiadiazol-5-yl]butanamide chemical structure, C15H19N3O2S, CAS 898613-42-8
2-Ethyl-N-[3-(4-methoxyphenyl)-1,2,4-thiadiazol-5-yl]butanamide
CAS 898613-42-8C15H19N3O2S
N-[3-(4-Fluorophenyl)-1,2,4-thiadiazol-5-yl]pentanamide chemical structure, C13H14FN3OS, CAS 898629-29-3
N-[3-(4-Fluorophenyl)-1,2,4-thiadiazol-5-yl]pentanamide
CAS 898629-29-3C13H14FN3OS
N-[3-(4-Fluorophenyl)-1,2,4-thiadiazol-5-yl]butanamide chemical structure, C12H12FN3OS, CAS 898629-31-7
N-[3-(4-Fluorophenyl)-1,2,4-thiadiazol-5-yl]butanamide
CAS 898629-31-7C12H12FN3OS
N-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]butanamide chemical structure, C12H12BrN3OS, CAS 898623-19-3
N-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]butanamide
CAS 898623-19-3C12H12BrN3OS
N-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]propanamide chemical structure, C11H10BrN3OS, CAS 898623-27-3
N-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]propanamide
CAS 898623-27-3C11H10BrN3OS
N-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]-3-methylbutanamide chemical structure, C13H14BrN3OS, CAS 898628-39-2
N-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]-3-methylbutanamide
CAS 898628-39-2C13H14BrN3OS
3-Methyl-N-(3-phenyl-1,2,4-thiadiazol-5-yl)butanamide chemical structure, C13H15N3OS, CAS 898491-47-9
3-Methyl-N-(3-phenyl-1,2,4-thiadiazol-5-yl)butanamide
CAS 898491-47-9C13H15N3OS
1,2,4-Thiadiazole-5-methanol, 3-[4-(trifluoromethyl)phenyl]- chemical structure, C10H7F3N2OS, CAS 851224-81-2
1,2,4-Thiadiazole-5-methanol, 3-[4-(trifluoromethyl)phenyl]-
CAS 851224-81-2C10H7F3N2OS
Ethyl 3-(4-(trifluoromethyl)phenyl)-1,2,4-thiadiazole-5-carboxylate chemical structure, C12H9F3N2O2S, CAS 851224-80-1
Ethyl 3-(4-(trifluoromethyl)phenyl)-1,2,4-thiadiazole-5-carboxylate
CAS 851224-80-1C12H9F3N2O2S
3-(4-Methylphenyl)-1,2,4-thiadiazol-5-amine chemical structure, C9H9N3S, CAS 898651-92-8
3-(4-Methylphenyl)-1,2,4-thiadiazol-5-amine
CAS 898651-92-8C9H9N3S
3-(3,4-Dimethoxyphenyl)-1,2,4-thiadiazol-5-amine chemical structure, C10H11N3O2S, CAS 889940-60-7
3-(3,4-Dimethoxyphenyl)-1,2,4-thiadiazol-5-amine
CAS 889940-60-7C10H11N3O2S
5-Chloro-3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazole chemical structure, C9H4ClF3N2S, CAS 138426-23-0
5-Chloro-3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazole
CAS 138426-23-0C9H4ClF3N2S
5-Chloro-3-(2-chlorophenyl)-1,2,4-thiadiazole chemical structure, C8H4Cl2N2S, CAS 160150-33-4
5-Chloro-3-(2-chlorophenyl)-1,2,4-thiadiazole
CAS 160150-33-4C8H4Cl2N2S
5-Chloro-3-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazole chemical structure, C9H4ClF3N2S, CAS 138426-29-6
5-Chloro-3-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazole
CAS 138426-29-6C9H4ClF3N2S
3-(5-Amino-1,2,4-thiadiazol-3-yl)benzene-1-sulfonic acid chemical structure, C8H7N3O3S2, CAS 331250-06-7
3-(5-Amino-1,2,4-thiadiazol-3-yl)benzene-1-sulfonic acid
CAS 331250-06-7C8H7N3O3S2
5-Chloro-3-(4-nitrophenyl)-1,2,4-thiadiazole chemical structure, C8H4ClN3O2S, CAS 88541-07-5
5-Chloro-3-(4-nitrophenyl)-1,2,4-thiadiazole
CAS 88541-07-5C8H4ClN3O2S
N''-[3-(4-Aminophenyl)-1,2,4-thiadiazol-5-yl]guanidine chemical structure, C9H10N6S, CAS 88540-99-2
N''-[3-(4-Aminophenyl)-1,2,4-thiadiazol-5-yl]guanidine
CAS 88540-99-2C9H10N6S
N''-[3-(4-Nitrophenyl)-1,2,4-thiadiazol-5-yl]guanidine chemical structure, C9H8N6O2S, CAS 88541-05-3
N''-[3-(4-Nitrophenyl)-1,2,4-thiadiazol-5-yl]guanidine
CAS 88541-05-3C9H8N6O2S
5-Chloro-3-(3-methylphenyl)-1,2,4-thiadiazole chemical structure, C9H7ClN2S, CAS 1221342-38-6
5-Chloro-3-(3-methylphenyl)-1,2,4-thiadiazole
CAS 1221342-38-6C9H7ClN2S
3-(o-Tolyl)-1,2,4-thiadiazol-5-amine chemical structure, C9H9N3S, CAS 1082251-12-4
3-(o-Tolyl)-1,2,4-thiadiazol-5-amine
CAS 1082251-12-4C9H9N3S