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Murcko scaffold

3-(1H-Pyrazol-1-yl)-1lambda6-thiolane-1,1-dione scaffold

67 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
67
With full pages
11
Scaffold SMILES

O=S1(=O)CCC(n2cccn2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(1H-Pyrazol-1-yl)-1lambda6-thiolane-1,1-dione page
Murcko scaffold O=S1(=O)CCC(n2cccn2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 67 chemicals

1-(1,1-Dioxothiolan-3-yl)pyrazole-4-carboxamide chemical structure, C8H11N3O3S, CAS 251096-51-2
1-(1,1-Dioxothiolan-3-yl)pyrazole-4-carboxamide
CAS 251096-51-2C8H11N3O3S
N-[(Dimethylamino)methylene]-1-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-1H-pyrazole-4-carboxamide chemical structure, C11H16N4O3S, CAS 251096-54-5
N-[(Dimethylamino)methylene]-1-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-1H-pyrazole-4-carboxamide
CAS 251096-54-5C11H16N4O3S
3-(5-Amino-3-methyl-1H-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C8H13N3O2S, CAS 27280-97-3
3-(5-Amino-3-methyl-1H-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 27280-97-3C8H13N3O2S
3-(3,5-Dimethyl-1H-pyrazol-1-yl)-1lambda6-thiolane-1,1-dione chemical structure, C9H14N2O2S, CAS 17115-84-3
3-(3,5-Dimethyl-1H-pyrazol-1-yl)-1lambda6-thiolane-1,1-dione
CAS 17115-84-3C9H14N2O2S
5-Chloro-1-(1,1-dioxidotetrahydrothien-3-yl)-3-methyl-1H-pyrazole-4-carbaldehyde chemical structure, C9H11ClN2O3S, CAS 885-44-9
5-Chloro-1-(1,1-dioxidotetrahydrothien-3-yl)-3-methyl-1H-pyrazole-4-carbaldehyde
CAS 885-44-9C9H11ClN2O3S
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3,5-dimethyl-1H-pyrazole-4-carbaldehyde chemical structure, C10H14N2O3S, CAS 955043-57-9
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3,5-dimethyl-1H-pyrazole-4-carbaldehyde
CAS 955043-57-9C10H14N2O3S
3-{3,5-Dimethyl-4-[(methylamino)methyl]-1H-pyrazol-1-yl}-1lambda6-thiolane-1,1-dione chemical structure, C11H19N3O2S, CAS 956437-74-4
3-{3,5-Dimethyl-4-[(methylamino)methyl]-1H-pyrazol-1-yl}-1lambda6-thiolane-1,1-dione
CAS 956437-74-4C11H19N3O2S
3-[5-Chloro-1-(1,1-dioxo-1lambda6-thiolan-3-yl)-3-methyl-1H-pyrazol-4-yl]prop-2-enoic acid chemical structure, C11H13ClN2O4S, CAS 956204-62-9
3-[5-Chloro-1-(1,1-dioxo-1lambda6-thiolan-3-yl)-3-methyl-1H-pyrazol-4-yl]prop-2-enoic acid
CAS 956204-62-9C11H13ClN2O4S
2-Chloro-N-[1-(1,1-dioxo-1lambda6-thiolan-3-yl)-3-methyl-1H-pyrazol-5-yl]acetamide chemical structure, C10H14ClN3O3S, CAS 956769-05-4
2-Chloro-N-[1-(1,1-dioxo-1lambda6-thiolan-3-yl)-3-methyl-1H-pyrazol-5-yl]acetamide
CAS 956769-05-4C10H14ClN3O3S
5-tert-Butyl-2-(1,1-dioxothiolan-3-yl)pyrazol-3-amine chemical structure, C11H19N3O2S, CAS 956571-71-4
5-tert-Butyl-2-(1,1-dioxothiolan-3-yl)pyrazol-3-amine
CAS 956571-71-4C11H19N3O2S
5-Amino-1-(1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carbonitrile chemical structure, C8H10N4O2S, CAS 956534-57-9
5-Amino-1-(1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carbonitrile
CAS 956534-57-9C8H10N4O2S
1-(1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-yl)-5-isopropyl-1H-pyrazole-3-carboxylic acid chemical structure, C11H16N2O4S, CAS 956610-87-0
1-(1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-yl)-5-isopropyl-1H-pyrazole-3-carboxylic acid
CAS 956610-87-0C11H16N2O4S
3-(4-(Hydroxymethyl)-3,5-dimethyl-1H-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C10H16N2O3S, CAS 926184-45-4
3-(4-(Hydroxymethyl)-3,5-dimethyl-1H-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 926184-45-4C10H16N2O3S
[1-(1,1-Dioxidotetrahydro-3-thienyl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid chemical structure, C11H16N2O4S, CAS 926235-14-5
[1-(1,1-Dioxidotetrahydro-3-thienyl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid
CAS 926235-14-5C11H16N2O4S
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-5-methyl-1H-pyrazole-4-carboxylic acid chemical structure, C9H12N2O4S, CAS 926260-88-0
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-5-methyl-1H-pyrazole-4-carboxylic acid
CAS 926260-88-0C9H12N2O4S
3-[1-(1,1-Dioxidotetrahydro-3-thienyl)-3,5-dimethyl-1H-pyrazol-4-yl]propanoic acid chemical structure, C12H18N2O4S, CAS 1052561-26-8
3-[1-(1,1-Dioxidotetrahydro-3-thienyl)-3,5-dimethyl-1H-pyrazol-4-yl]propanoic acid
CAS 1052561-26-8C12H18N2O4S
Ethyl 5-amino-1-(1,1-dioxo-1lambda6-thiolan-3-yl)-1H-pyrazole-4-carboxylate chemical structure, C10H15N3O4S, CAS 1010863-54-3
Ethyl 5-amino-1-(1,1-dioxo-1lambda6-thiolan-3-yl)-1H-pyrazole-4-carboxylate
CAS 1010863-54-3C10H15N3O4S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid chemical structure, C10H14N2O4S, CAS 1134555-25-1
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid
CAS 1134555-25-1C10H14N2O4S
2-Chloro-1-(1-(1,1-dioxidotetrahydrothiophen-3-yl)-3,5-dimethyl-1H-pyrazol-4-yl)ethanone chemical structure, C11H15ClN2O3S, CAS 1134694-06-6
2-Chloro-1-(1-(1,1-dioxidotetrahydrothiophen-3-yl)-3,5-dimethyl-1H-pyrazol-4-yl)ethanone
CAS 1134694-06-6C11H15ClN2O3S
1-(1,1-Dioxothiolan-3-yl)pyrazole-4-carboxylic acid chemical structure, C8H10N2O4S, CAS 1134714-88-7
1-(1,1-Dioxothiolan-3-yl)pyrazole-4-carboxylic acid
CAS 1134714-88-7C8H10N2O4S
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C8H10N2O3S, CAS 1134423-12-3
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 1134423-12-3C8H10N2O3S
3,5-Dimethyl-1-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C11H16N2O4S, CAS 1170990-64-3
3,5-Dimethyl-1-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carboxylic acid
CAS 1170990-64-3C11H16N2O4S
3,5-Dimethyl-1-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C11H16N2O3S, CAS 1170905-20-0
3,5-Dimethyl-1-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 1170905-20-0C11H16N2O3S
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3-(propan-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C11H16N2O4S, CAS 1152509-17-5
1-(1,1-Dioxo-1lambda6-thiolan-3-yl)-3-(propan-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 1152509-17-5C11H16N2O4S