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Murcko scaffold

N-[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide scaffold

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
15
With full pages
3
Scaffold SMILES

O=C(NCc1nc(-c2ccccc2)no1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide page
Murcko scaffold O=C(NCc1nc(-c2ccccc2)no1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

N-[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide chemical structure, C14H11N3O2S, CAS 717828-81-4
N-[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide
CAS 717828-81-4C14H11N3O2S
N-{[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-isopropyl-2-thiophenecarboxamide chemical structure, C17H16ClN3O2S, CAS 708283-97-0
N-{[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-isopropyl-2-thiophenecarboxamide
CAS 708283-97-0C17H16ClN3O2S
N-{[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-(propan-2-yl)thiophene-2-carboxamide chemical structure, C18H19N3O2S, CAS 717833-57-3
N-{[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-(propan-2-yl)thiophene-2-carboxamide
CAS 717833-57-3C18H19N3O2S
N-[[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide chemical structure, C14H10ClN3O2S, CAS 839680-76-1
N-[[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide
CAS 839680-76-1C14H10ClN3O2S
N-[[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide chemical structure, C14H10ClN3O2S, CAS 876902-91-9
N-[[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide
CAS 876902-91-9C14H10ClN3O2S
N-[[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide chemical structure, C16H15N3O4S, CAS 876666-86-3
N-[[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide
CAS 876666-86-3C16H15N3O4S
N-Methyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]thiophene-2-carboxamide chemical structure, C15H13N3O2S, CAS 878432-55-4
N-Methyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]thiophene-2-carboxamide
CAS 878432-55-4C15H13N3O2S
N-[[3-(3-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-prop-2-enylthiophene-2-carboxamide chemical structure, C18H17N3O2S, CAS 878432-79-2
N-[[3-(3-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-prop-2-enylthiophene-2-carboxamide
CAS 878432-79-2C18H17N3O2S
N-[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]-N-prop-2-enylthiophene-2-carboxamide chemical structure, C17H15N3O2S, CAS 878432-65-6
N-[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]-N-prop-2-enylthiophene-2-carboxamide
CAS 878432-65-6C17H15N3O2S
N-Ethyl-N-{[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}thiophene-2-carboxamide chemical structure, C17H17N3O3S, CAS 878432-94-1
N-Ethyl-N-{[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}thiophene-2-carboxamide
CAS 878432-94-1C17H17N3O3S
N-Ethyl-N-{[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}thiophene-2-carboxamide chemical structure, C17H17N3O2S, CAS 878432-75-8
N-Ethyl-N-{[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}thiophene-2-carboxamide
CAS 878432-75-8C17H17N3O2S
N-Methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide chemical structure, C16H15N3O2S, CAS 878432-70-3
N-Methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]thiophene-2-carboxamide
CAS 878432-70-3C16H15N3O2S
N-{[3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-methylthiophene-2-carboxamide chemical structure, C16H15N3O3S, CAS 878432-89-4
N-{[3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-N-methylthiophene-2-carboxamide
CAS 878432-89-4C16H15N3O3S
N-[[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-prop-2-enylthiophene-2-carboxamide chemical structure, C18H17N3O2S, CAS 887688-61-1
N-[[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-prop-2-enylthiophene-2-carboxamide
CAS 887688-61-1C18H17N3O2S
N-tert-Butyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]thiophene-2-carboxamide chemical structure, C18H19N3O2S, CAS 878995-44-9
N-tert-Butyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]thiophene-2-carboxamide
CAS 878995-44-9C18H19N3O2S