Murcko scaffold
Ring system with 4 rings and 23 atoms
1,683 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 1,683
- With full pages
- 15
Scaffold SMILES
O=C(NC1CCCC1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 1,683 chemicals
(1R,3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-1,2,2-trimethylcyclopentane-1-carboxylic acid
CAS 2550996-56-8C24H27NO4
![3-[(1S,3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)cyclopentyl]propanoic acid chemical structure, C23H25NO4, CAS 2445749-54-0](/s/DRPYBDQKTVOADQ-HOTGVXAUSA-N.svg)
3-[(1S,3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)cyclopentyl]propanoic acid
CAS 2445749-54-0C23H25NO4
![3-[Cyclopentyl(9H-fluoren-9-ylmethoxycarbonyl)amino]-2,2-dimethylpropanoic acid chemical structure, C25H29NO4, CAS 2580200-02-6](/s/JZRATWKNWBVKGI-UHFFFAOYSA-N.svg)
3-[Cyclopentyl(9H-fluoren-9-ylmethoxycarbonyl)amino]-2,2-dimethylpropanoic acid
CAS 2580200-02-6C25H29NO4
(1S,3S)-1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylcyclopentane-1-carboxylic acid
CAS 1932259-59-0C22H23NO4
![Rac-5-{1-[(1r,3s)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-methylformamido}pentanoic acid chemical structure, C27H32N2O5, CAS 2227754-24-5](/s/PREDCPYLZSSQFG-RBUKOAKNSA-N.svg)
Rac-5-{1-[(1r,3s)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-methylformamido}pentanoic acid
CAS 2227754-24-5C27H32N2O5
![Chloromethyl 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentane-1-carboxylate chemical structure, C28H33ClN2O6, CAS 2137700-94-6](/s/FCXQCHWLXSOOJO-UHFFFAOYSA-N.svg)
Chloromethyl 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentane-1-carboxylate
CAS 2137700-94-6C28H33ClN2O6
![3-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-2-(propan-2-yl)butanoic acid chemical structure, C28H34N2O5, CAS 2172565-42-1](/s/PDELVEYIDZKLFC-UHFFFAOYSA-N.svg)
3-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-2-(propan-2-yl)butanoic acid
CAS 2172565-42-1C28H34N2O5
![(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-3-methoxypropanoic acid chemical structure, C25H28N2O6, CAS 2648927-19-7](/s/DKQCBDPEEBXBSP-LGHDPPOTSA-N.svg)
(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-3-methoxypropanoic acid
CAS 2648927-19-7C25H28N2O6
![2-(2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}acetamido)acetic acid chemical structure, C25H27N3O6, CAS 2171939-29-8](/s/NEBUKWCGXKLSSC-UHFFFAOYSA-N.svg)
2-(2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}acetamido)acetic acid
CAS 2171939-29-8C25H27N3O6
![3-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}hexanoic acid chemical structure, C28H34N2O5, CAS 2172371-23-0](/s/UJKVBVNWWHJTSE-UHFFFAOYSA-N.svg)
3-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}hexanoic acid
CAS 2172371-23-0C28H34N2O5
![2-{1-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(2-methylpropyl)formamido}acetic acid chemical structure, C27H32N2O5, CAS 2172084-46-5](/s/ABUQMWZNKCBTHB-UHFFFAOYSA-N.svg)
2-{1-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(2-methylpropyl)formamido}acetic acid
CAS 2172084-46-5C27H32N2O5
![3-(Dimethylamino)-2-{2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}propanoic acid chemical structure, C27H33N3O5, CAS 2171714-68-2](/s/FAXSWIJTJSZGAH-UHFFFAOYSA-N.svg)
3-(Dimethylamino)-2-{2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}propanoic acid
CAS 2171714-68-2C27H33N3O5
![2-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}pent-4-ynoic acid chemical structure, C26H26N2O5, CAS 2171756-74-2](/s/LNHRNOFHHXXVCZ-UHFFFAOYSA-N.svg)
2-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}pent-4-ynoic acid
CAS 2171756-74-2C26H26N2O5
![3-{N-Ethyl-1-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-2-methylpropanoic acid chemical structure, C27H32N2O5, CAS 2172519-61-6](/s/ZNOYSMRMXKUIPB-UHFFFAOYSA-N.svg)
3-{N-Ethyl-1-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-2-methylpropanoic acid
CAS 2172519-61-6C27H32N2O5
![2-{N-Ethyl-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}acetic acid chemical structure, C26H30N2O5, CAS 2172132-83-9](/s/MYRYAFGGZKAXDZ-UHFFFAOYSA-N.svg)
2-{N-Ethyl-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}acetic acid
CAS 2172132-83-9C26H30N2O5
![(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}butanoic acid chemical structure, C26H30N2O5, CAS 2171428-84-3](/s/NMCZOYWHDUIBHH-OCJFHSIUSA-N.svg)
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}butanoic acid
CAS 2171428-84-3C26H30N2O5
![2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-3,3,3-trifluoro-2-methylpropanoic acid chemical structure, C25H25F3N2O5, CAS 2171819-71-7](/s/HJSJAVLNFUCKGM-UHFFFAOYSA-N.svg)
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-3,3,3-trifluoro-2-methylpropanoic acid
CAS 2171819-71-7C25H25F3N2O5
![4-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentyl]formamido}-3,3-dimethylbutanoic acid chemical structure, C28H34N2O5, CAS 2171941-55-0](/s/NSPVSRMURFPVBL-UHFFFAOYSA-N.svg)
4-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentyl]formamido}-3,3-dimethylbutanoic acid
CAS 2171941-55-0C28H34N2O5
![(3S)-3-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}heptanoic acid chemical structure, C28H34N2O5, CAS 2171439-11-3](/s/HVMDWMVSDLIVTP-KETPHWKMSA-N.svg)
(3S)-3-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}heptanoic acid
CAS 2171439-11-3C28H34N2O5
![(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}-3-methoxypropanoic acid chemical structure, C26H30N2O6, CAS 2648913-15-7](/s/BNQJSJMMZGRWLT-OCJFHSIUSA-N.svg)
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}-3-methoxypropanoic acid
CAS 2648913-15-7C26H30N2O6
![2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}-3-methoxy-2-methylpropanoic acid chemical structure, C27H32N2O6, CAS 2171952-94-4](/s/DRTFEVMFCPKELY-UHFFFAOYSA-N.svg)
2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}-3-methoxy-2-methylpropanoic acid
CAS 2171952-94-4C27H32N2O6
![3-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}heptanoic acid chemical structure, C28H34N2O5, CAS 2171839-22-6](/s/ILXVYRKADNYHLR-UHFFFAOYSA-N.svg)
3-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}heptanoic acid
CAS 2171839-22-6C28H34N2O5
![2-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}hex-4-ynoic acid chemical structure, C27H28N2O5, CAS 2171694-00-9](/s/KYZJMGQTBHWOCE-UHFFFAOYSA-N.svg)
2-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}hex-4-ynoic acid
CAS 2171694-00-9C27H28N2O5
![1-Ethyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentane-1-carboxylic acid chemical structure, C23H25NO4, CAS 2138142-03-5](/s/AMZCWFFINZLEMF-UHFFFAOYSA-N.svg)
1-Ethyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentane-1-carboxylic acid
CAS 2138142-03-5C23H25NO4
- 2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(prop-2-yn-1-yl)acetamido}acetic acid2171855-93-7C27H28N2O5
- 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-1,4,4-trimethylcyclopentane-1-carboxylic acid2137829-75-3C24H27NO4
- 4-Ethyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentane-1-carboxylic acid2138304-79-5C24H27NO4
- 5-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-3-methylpentanoic acid2172136-96-6C27H32N2O5
- 2-{1-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(propan-2-yl)formamido}acetic acid2172218-31-2C26H30N2O5
- (2R)-2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}pentanoic acid2171286-10-3C26H30N2O5
- 4-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-2-methylbut-2-enoic acid2172609-88-8C26H28N2O5
- (3R)-3-{2-[(1RS,2SR)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}pentanoic acid2227857-12-5C27H32N2O5
- 2-{2-[Cyclopentyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetamido}pent-4-enoic acid2137505-86-1C27H30N2O5
- 2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(2-hydroxyethyl)acetamido}acetic acid2171917-98-7C26H30N2O6
- 4-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-4-methylpentanoic acid2172148-89-7C27H32N2O5
- 2-({1-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-methylformamido}oxy)acetic acid2172393-59-6C24H26N2O6
- 2-({2-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-methylacetamido}oxy)acetic acid2171869-75-1C25H28N2O6
- rac-2-({2-[(1R,2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-methylacetamido}oxy)acetic acid2227763-62-2C25H28N2O6
- 2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-3,3-dimethylbutanoic acid2171465-95-3C27H32N2O5
- 4-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-2,2-dimethylbutanoic acid2172217-22-8C27H32N2O5
- 2-[N-(Butan-2-yl)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido]acetic acid2171972-72-6C28H34N2O5
- 2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(propan-2-yl)acetamido}acetic acid2172033-33-7C27H32N2O5
- 2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-methylacetamido}acetic acid2172183-37-6C25H28N2O5
- (2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}-3-hydroxypropanoic acid2648935-60-6C25H28N2O6
- 2-{1-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(2-methoxyethyl)formamido}acetic acid2171820-95-2C26H30N2O6
- 2-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentyl]formamido}-2-methylpentanoic acid2171801-72-0C28H34N2O5
- (2S)-2-{[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentyl]formamido}-4-(methylsulfanyl)butanoic acid2648926-33-2C27H32N2O5S
- 4-[(2-{[(tert-Butoxy)carbonyl]amino}cyclopentyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]butanoic acid2138126-15-3C29H36N2O6
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NC1CCNC1)OCC1c2ccccc2-c2ccccc218 chemicals
O=C(NC1CCOC1)OCC1c2ccccc2-c2ccccc215 chemicals![Scaffold O=C(Nc1cn[nH]c1)OCC1c2ccccc2-c2ccccc21](/scaffold/GRYNIMLLGMUFHI-UHFFFAOYSA-N/structure.svg)
O=C(Nc1cn[nH]c1)OCC1c2ccccc2-c2ccccc214 chemicals
O=C(NC1CCNC1=O)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(Nc1ccn[nH]1)OCC1c2ccccc2-c2ccccc21](/scaffold/FLEVPWMMBRYGKK-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccn[nH]1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NN=Cc1cn[nH]c1)C1c2ccccc2-c2ccccc21](/scaffold/GTQCBQXRCMODFH-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1cn[nH]c1)C1c2ccccc2-c2ccccc212 chemicals
c1ccc2c(c1)c1ccccc1n2CCCNC1CCCC11 chemical
O=C(NN=Cc1ccco1)C1c2ccccc2-c2ccccc211 chemical
O=C(Nc1ccsc1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(NC1CC=CC1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(NC1C=CCC1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O1 chemical