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Murcko scaffold

2-Benzyl-3,4-dihydro-1H-isoquinoline scaffold

146 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
146
With full pages
17
Scaffold SMILES

c1ccc(CN2CCc3ccccc3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzyl-3,4-dihydro-1H-isoquinoline page
Murcko scaffold c1ccc(CN2CCc3ccccc3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 146 chemicals

Isoquinoline, 1,2,3,4-tetrahydro-2-(phenylmethyl)-, hydrochloride (1:1) chemical structure, C16H18ClN, CAS 10166-07-1
Isoquinoline, 1,2,3,4-tetrahydro-2-(phenylmethyl)-, hydrochloride (1:1)
CAS 10166-07-1C16H18ClN
2-Benzyl-3,4-dihydro-1H-isoquinoline chemical structure, C16H17N, CAS 13605-95-3
2-Benzyl-3,4-dihydro-1H-isoquinoline
CAS 13605-95-3C16H17N
N-Benzyl salsolidine chemical structure, C19H23NO2, CAS 19902-16-0
N-Benzyl salsolidine
CAS 19902-16-0C19H23NO2
Isoquinoline, 1,2,3,4-tetrahydro-2-benzyl-6,7-dimethoxy-, hydrobromide chemical structure, C18H22BrNO2, CAS 31756-15-7
Isoquinoline, 1,2,3,4-tetrahydro-2-benzyl-6,7-dimethoxy-, hydrobromide
CAS 31756-15-7C18H22BrNO2
2-Benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline chemical structure, C18H21NO2, CAS 5267-52-7
2-Benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
CAS 5267-52-7C18H21NO2
Isoquinoline, 1,2,3,4-tetrahydro-2-(p-chlorobenzyl)-6,7-dimethoxy-, hydrobromide chemical structure, C18H21BrClNO2, CAS 31756-22-6
Isoquinoline, 1,2,3,4-tetrahydro-2-(p-chlorobenzyl)-6,7-dimethoxy-, hydrobromide
CAS 31756-22-6C18H21BrClNO2
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(o-fluorobenzyl)-, hydrobromide chemical structure, C18H21BrFNO2, CAS 31756-24-8
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(o-fluorobenzyl)-, hydrobromide
CAS 31756-24-8C18H21BrFNO2
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(m-fluorobenzyl)-, hydrobromide chemical structure, C18H21BrFNO2, CAS 31756-26-0
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(m-fluorobenzyl)-, hydrobromide
CAS 31756-26-0C18H21BrFNO2
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(p-fluorobenzyl)-, hydrobromide chemical structure, C18H21BrFNO2, CAS 31756-28-2
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(p-fluorobenzyl)-, hydrobromide
CAS 31756-28-2C18H21BrFNO2
2-[(4-Fluorophenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline chemical structure, C18H20FNO2, CAS 5267-13-0
2-[(4-Fluorophenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline
CAS 5267-13-0C18H20FNO2
Isoquinoline, 1,2,3,4-tetrahydro-2-(o-chlorobenzyl)-6,7-dimethoxy-, hydrobromide chemical structure, C18H21BrClNO2, CAS 31772-98-2
Isoquinoline, 1,2,3,4-tetrahydro-2-(o-chlorobenzyl)-6,7-dimethoxy-, hydrobromide
CAS 31772-98-2C18H21BrClNO2
2-Benzyl-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1) chemical structure, C16H18ClNO2, CAS 79677-15-9
2-Benzyl-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1)
CAS 79677-15-9C16H18ClNO2
2-Benzyl-1-methyl-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1) chemical structure, C17H20ClNO2, CAS 93202-97-2
2-Benzyl-1-methyl-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1)
CAS 93202-97-2C17H20ClNO2
Isoquinoline, 1,2,3,4-tetrahydro-2-benzyl-3-chloromethyl-, hydrochloride chemical structure, C17H19Cl2N, CAS 101573-65-3
Isoquinoline, 1,2,3,4-tetrahydro-2-benzyl-3-chloromethyl-, hydrochloride
CAS 101573-65-3C17H19Cl2N
Benzenamine, 2-((3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl)-4-methyl- chemical structure, C19H24N2O2, CAS 35690-53-0
Benzenamine, 2-((3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl)-4-methyl-
CAS 35690-53-0C19H24N2O2
2-Benzyl-7-nitro-1,2,3,4-tetrahydroisoquinoline chemical structure, C16H16N2O2, CAS 444588-09-4
2-Benzyl-7-nitro-1,2,3,4-tetrahydroisoquinoline
CAS 444588-09-4C16H16N2O2
N-tert-Butyl-4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)benzamide chemical structure, C21H26N2O, CAS 333358-00-2
N-tert-Butyl-4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)benzamide
CAS 333358-00-2C21H26N2O
4-(3,4-Dihydro-2(1H)-isoquinolinylmethyl)benzoic acid chemical structure, C17H17NO2, CAS 333357-96-3
4-(3,4-Dihydro-2(1H)-isoquinolinylmethyl)benzoic acid
CAS 333357-96-3C17H17NO2
Methyl 4-[(3,4-dihydro-2(1H)-isoquinolinyl)methyl]benzoate chemical structure, C18H19NO2, CAS 331750-25-5
Methyl 4-[(3,4-dihydro-2(1H)-isoquinolinyl)methyl]benzoate
CAS 331750-25-5C18H19NO2
Cambridge id 5258124 chemical structure, C16H16N2O2, CAS 70638-30-1
Cambridge id 5258124
CAS 70638-30-1C16H16N2O2
6,7-Dimethoxy-2-[(4-nitrophenyl)methyl]-3,4-dihydro-1H-isoquinoline chemical structure, C18H20N2O4, CAS 103143-17-5
6,7-Dimethoxy-2-[(4-nitrophenyl)methyl]-3,4-dihydro-1H-isoquinoline
CAS 103143-17-5C18H20N2O4
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-2-methoxyphenol chemical structure, C17H19NO2, CAS 375828-85-6
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-2-methoxyphenol
CAS 375828-85-6C17H19NO2
2-[(2,5-Dimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinoline chemical structure, C18H21NO2, CAS 414887-60-8
2-[(2,5-Dimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinoline
CAS 414887-60-8C18H21NO2
2-[(2-Chloro-5-nitrophenyl)methyl]-3,4-dihydro-1H-isoquinoline chemical structure, C16H15ClN2O2, CAS 414893-82-6
2-[(2-Chloro-5-nitrophenyl)methyl]-3,4-dihydro-1H-isoquinoline
CAS 414893-82-6C16H15ClN2O2