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Murcko scaffold

2-Benzyl-3,4-dihydro-1H-isoquinoline scaffold

146 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
146
With full pages
17
Scaffold SMILES

c1ccc(CN2CCc3ccccc3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzyl-3,4-dihydro-1H-isoquinoline page
Murcko scaffold c1ccc(CN2CCc3ccccc3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 146 of 146 chemicals

2,6-Dimethoxy-4-((1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)methyl)phenol chemical structure, C19H23NO3, CAS 2450624-57-2
2,6-Dimethoxy-4-((1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)methyl)phenol
CAS 2450624-57-2C19H23NO3
Hdac6-IN-77 chemical structure, C17H16ClFN2O2, CAS 3126891-54-8
Hdac6-IN-77
CAS 3126891-54-8C17H16ClFN2O2