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Murcko scaffold

N-(1,3-Dioxoisoindol-2-yl)benzamide scaffold

32 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
32
With full pages
10
Scaffold SMILES

O=C(NN1C(=O)c2ccccc2C1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Dioxoisoindol-2-yl)benzamide page
Murcko scaffold O=C(NN1C(=O)c2ccccc2C1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

N-(1,3-Dioxoisoindol-2-yl)benzamide chemical structure, C15H10N2O3, CAS 16067-65-5
N-(1,3-Dioxoisoindol-2-yl)benzamide
CAS 16067-65-5C15H10N2O3
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methoxybenzamide chemical structure, C16H12N2O4, CAS 118071-20-8
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methoxybenzamide
CAS 118071-20-8C16H12N2O4
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3,5-dihydroxybenzamide chemical structure, C15H10N2O5, CAS 304455-17-2
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3,5-dihydroxybenzamide
CAS 304455-17-2C15H10N2O5
3-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)carbamoyl]phenyl acetate chemical structure, C17H12N2O5, CAS 404365-54-4
3-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)carbamoyl]phenyl acetate
CAS 404365-54-4C17H12N2O5
3-Chloro-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzamide chemical structure, C15H9ClN2O3, CAS 304456-93-7
3-Chloro-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzamide
CAS 304456-93-7C15H9ClN2O3
N-(1,3-Dioxoisoindol-2-yl)-2,6-dimethoxybenzamide chemical structure, C17H14N2O5, CAS 337502-47-3
N-(1,3-Dioxoisoindol-2-yl)-2,6-dimethoxybenzamide
CAS 337502-47-3C17H14N2O5
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-nitrobenzamide chemical structure, C15H9N3O5, CAS 330966-66-0
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-nitrobenzamide
CAS 330966-66-0C15H9N3O5
N-(1,3-Dioxoisoindol-2-yl)-4-ethoxybenzamide chemical structure, C17H14N2O4, CAS 332382-46-4
N-(1,3-Dioxoisoindol-2-yl)-4-ethoxybenzamide
CAS 332382-46-4C17H14N2O4
N-(1,3-Dioxoisoindol-2-yl)-4-hydroxybenzamide chemical structure, C15H10N2O4, CAS 296791-43-0
N-(1,3-Dioxoisoindol-2-yl)-4-hydroxybenzamide
CAS 296791-43-0C15H10N2O4
4-tert-Butyl-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzamide chemical structure, C19H18N2O3, CAS 514811-69-9
4-tert-Butyl-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzamide
CAS 514811-69-9C19H18N2O3
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-nitrobenzamide chemical structure, C15H9N3O5, CAS 305856-19-3
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-nitrobenzamide
CAS 305856-19-3C15H9N3O5
4-Chloro-N-(1,3-dioxoisoindol-2-yl)benzamide chemical structure, C15H9ClN2O3, CAS 314765-82-7
4-Chloro-N-(1,3-dioxoisoindol-2-yl)benzamide
CAS 314765-82-7C15H9ClN2O3
4-Hydroxy-N-(5-nitro-1,3-dioxoisoindol-2-yl)benzamide chemical structure, C15H9N3O6, CAS 351983-40-9
4-Hydroxy-N-(5-nitro-1,3-dioxoisoindol-2-yl)benzamide
CAS 351983-40-9C15H9N3O6
N-(1,3-Dioxoisoindol-2-yl)-3-methyl-4-nitrobenzamide chemical structure, C16H11N3O5, CAS 420842-89-3
N-(1,3-Dioxoisoindol-2-yl)-3-methyl-4-nitrobenzamide
CAS 420842-89-3C16H11N3O5
2-(Benzoylamino)-1,3-dioxo-5-isoindolinecarboxylic acid chemical structure, C16H10N2O5, CAS 211565-51-4
2-(Benzoylamino)-1,3-dioxo-5-isoindolinecarboxylic acid
CAS 211565-51-4C16H10N2O5
N-(1,3-Dioxoisoindol-2-yl)-2-hydroxybenzamide chemical structure, C15H10N2O4, CAS 57187-42-5
N-(1,3-Dioxoisoindol-2-yl)-2-hydroxybenzamide
CAS 57187-42-5C15H10N2O4
2-(4-Hydroxybenzamido)-1,3-dioxoisoindoline-5-carboxylic acid chemical structure, C16H10N2O6, CAS 577982-36-6
2-(4-Hydroxybenzamido)-1,3-dioxoisoindoline-5-carboxylic acid
CAS 577982-36-6C16H10N2O6
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylbenzamide chemical structure, C16H12N2O3, CAS 131526-97-1
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylbenzamide
CAS 131526-97-1C16H12N2O3
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3,4,5-trimethoxybenzamide chemical structure, C18H16N2O6, CAS 356526-72-2
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3,4,5-trimethoxybenzamide
CAS 356526-72-2C18H16N2O6
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-iodo-4-methoxybenzamide chemical structure, C16H11IN2O4, CAS 315675-46-8
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-iodo-4-methoxybenzamide
CAS 315675-46-8C16H11IN2O4
4-(Butyrylamino)-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzamide chemical structure, C19H17N3O4, CAS 327065-75-8
4-(Butyrylamino)-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzamide
CAS 327065-75-8C19H17N3O4
3-Bromo-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methoxybenzamide chemical structure, C16H11BrN2O4, CAS 356764-47-1
3-Bromo-N-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methoxybenzamide
CAS 356764-47-1C16H11BrN2O4
N-(5-Bromo-1,3-dioxoisoindol-2-yl)-3-methoxybenzamide chemical structure, C16H11BrN2O4, CAS 354157-13-4
N-(5-Bromo-1,3-dioxoisoindol-2-yl)-3-methoxybenzamide
CAS 354157-13-4C16H11BrN2O4
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-iodobenzamide chemical structure, C15H9IN2O3, CAS 314282-64-9
N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-iodobenzamide
CAS 314282-64-9C15H9IN2O3