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Murcko scaffold

2-Propen-1-one, 1-[4-(benzoyloxy)phenyl]-3-phenyl- scaffold

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
22
With full pages
3
Scaffold SMILES

O=C(C=Cc1ccccc1)c1ccc(OC(=O)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Propen-1-one, 1-[4-(benzoyloxy)phenyl]-3-phenyl- page
Murcko scaffold O=C(C=Cc1ccccc1)c1ccc(OC(=O)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

4-[3-[4-(1-Methylethyl)phenyl]-1-oxo-2-propen-1-yl]phenyl 4-(1,1-dimethylethyl)benzoate chemical structure, C29H30O3, CAS 306730-16-5
4-[3-[4-(1-Methylethyl)phenyl]-1-oxo-2-propen-1-yl]phenyl 4-(1,1-dimethylethyl)benzoate
CAS 306730-16-5C29H30O3
2-Propen-1-one, 1-[4-(benzoyloxy)phenyl]-3-phenyl- chemical structure, C22H16O3, CAS 102468-57-5
2-Propen-1-one, 1-[4-(benzoyloxy)phenyl]-3-phenyl-
CAS 102468-57-5C22H16O3
Benzoic acid, 4-methyl-, 4-(1-oxo-3-phenyl-2-propenyl)phenyl ester chemical structure, C23H18O3, CAS 111819-11-5
Benzoic acid, 4-methyl-, 4-(1-oxo-3-phenyl-2-propenyl)phenyl ester
CAS 111819-11-5C23H18O3
4-[3-(4-Fluorophenyl)acryloyl]phenyl 4-(trifluoromethyl)benzoate chemical structure, C23H14F4O3, CAS 279691-57-5
4-[3-(4-Fluorophenyl)acryloyl]phenyl 4-(trifluoromethyl)benzoate
CAS 279691-57-5C23H14F4O3
4-[3-(2,3,4-Trimethoxyphenyl)acryloyl]phenyl 4-(trifluoromethyl)benzoate chemical structure, C26H21F3O6, CAS 279691-62-2
4-[3-(2,3,4-Trimethoxyphenyl)acryloyl]phenyl 4-(trifluoromethyl)benzoate
CAS 279691-62-2C26H21F3O6
4-[3-(2,4-Dimethoxyphenyl)acryloyl]phenyl 4-chlorobenzoate chemical structure, C24H19ClO5, CAS 331461-54-2
4-[3-(2,4-Dimethoxyphenyl)acryloyl]phenyl 4-chlorobenzoate
CAS 331461-54-2C24H19ClO5
[4-[(E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl] 4-methylbenzoate chemical structure, C23H17ClO3, CAS 329777-47-1
[4-[(E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl] 4-methylbenzoate
CAS 329777-47-1C23H17ClO3
4-[(E)-3-(4-Isopropylphenyl)-2-propenoyl]phenyl 4-nitrobenzenecarboxylate chemical structure, C25H21NO5, CAS 306730-00-7
4-[(E)-3-(4-Isopropylphenyl)-2-propenoyl]phenyl 4-nitrobenzenecarboxylate
CAS 306730-00-7C25H21NO5
4-[3-(2,3,4-Trimethoxyphenyl)acryloyl]phenyl 4-nitrobenzenecarboxylate chemical structure, C25H21NO8, CAS 288306-48-9
4-[3-(2,3,4-Trimethoxyphenyl)acryloyl]phenyl 4-nitrobenzenecarboxylate
CAS 288306-48-9C25H21NO8
4-[3-(5-Bromo-2-methoxyphenyl)acryloyl]phenyl 4-methylbenzenecarboxylate chemical structure, C24H19BrO4, CAS 306730-04-1
4-[3-(5-Bromo-2-methoxyphenyl)acryloyl]phenyl 4-methylbenzenecarboxylate
CAS 306730-04-1C24H19BrO4
4-[(2E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl 3-nitrobenzoate chemical structure, C22H14ClNO5, CAS 298216-10-1
4-[(2E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl 3-nitrobenzoate
CAS 298216-10-1C22H14ClNO5
4-[3-(2,3,4-Trimethoxyphenyl)acryloyl]phenyl 4-(tert-butyl)benzenecarboxylate chemical structure, C29H30O6, CAS 288306-49-0
4-[3-(2,3,4-Trimethoxyphenyl)acryloyl]phenyl 4-(tert-butyl)benzenecarboxylate
CAS 288306-49-0C29H30O6
[4-[(E)-3-(4-Fluorophenyl)prop-2-enoyl]phenyl] 4-methylbenzoate chemical structure, C23H17FO3, CAS 329704-19-0
[4-[(E)-3-(4-Fluorophenyl)prop-2-enoyl]phenyl] 4-methylbenzoate
CAS 329704-19-0C23H17FO3
4-{(2E)-3-[4-(Methylethyl)phenyl]prop-2-enoyl}phenyl 4-methylbenzoate chemical structure, C26H24O3, CAS 306730-02-9
4-{(2E)-3-[4-(Methylethyl)phenyl]prop-2-enoyl}phenyl 4-methylbenzoate
CAS 306730-02-9C26H24O3
4-[3-(2-Chlorophenyl)acryloyl]phenyl 4-(tert-butyl)benzenecarboxylate chemical structure, C26H23ClO3, CAS 331461-31-5
4-[3-(2-Chlorophenyl)acryloyl]phenyl 4-(tert-butyl)benzenecarboxylate
CAS 331461-31-5C26H23ClO3
4-[3-(5-Bromo-2-methoxyphenyl)acryloyl]phenyl 4-(tert-butyl)benzenecarboxylate chemical structure, C27H25BrO4, CAS 306730-17-6
4-[3-(5-Bromo-2-methoxyphenyl)acryloyl]phenyl 4-(tert-butyl)benzenecarboxylate
CAS 306730-17-6C27H25BrO4
4-[3-(2,4-Dimethoxyphenyl)acryloyl]phenyl 3-nitrobenzenecarboxylate chemical structure, C24H19NO7, CAS 331461-70-2
4-[3-(2,4-Dimethoxyphenyl)acryloyl]phenyl 3-nitrobenzenecarboxylate
CAS 331461-70-2C24H19NO7
4-[(2E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl 4-chlorobenzoate chemical structure, C22H14Cl2O3, CAS 298215-99-3
4-[(2E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl 4-chlorobenzoate
CAS 298215-99-3C22H14Cl2O3
4-(3-(3-Chlorophenyl)acryloyl)phenyl 2-fluorobenzenecarboxylate chemical structure, C22H14ClFO3, CAS 298216-00-9
4-(3-(3-Chlorophenyl)acryloyl)phenyl 2-fluorobenzenecarboxylate
CAS 298216-00-9C22H14ClFO3
[4-[(E)-3-(2,3,4-Trimethoxyphenyl)prop-2-enoyl]phenyl] 4-methylbenzoate chemical structure, C26H24O6, CAS 306730-05-2
[4-[(E)-3-(2,3,4-Trimethoxyphenyl)prop-2-enoyl]phenyl] 4-methylbenzoate
CAS 306730-05-2C26H24O6
4-[(2Z)-3-(2,4-Dichlorophenyl)prop-2-enoyl]phenyl 4-methylbenzoate chemical structure, C23H16Cl2O3, CAS 306729-99-7
4-[(2Z)-3-(2,4-Dichlorophenyl)prop-2-enoyl]phenyl 4-methylbenzoate
CAS 306729-99-7C23H16Cl2O3
4-[(2Z)-3-(5-Bromo-2-methoxyphenyl)prop-2-enoyl]phenyl 4-chlorobenzoate chemical structure, C23H16BrClO4, CAS 306730-28-9
4-[(2Z)-3-(5-Bromo-2-methoxyphenyl)prop-2-enoyl]phenyl 4-chlorobenzoate
CAS 306730-28-9C23H16BrClO4