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Murcko scaffold

Ring system with 3 rings and 16 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
5
With full pages
3
Scaffold SMILES

c1cc2cnc(CN3CCCCC3)nc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2cnc(CN3CCCCC3)nc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

4-Chloro-5,6-dimethyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidine chemical structure, C14H18ClN3S, CAS 731827-05-7
4-Chloro-5,6-dimethyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidine
CAS 731827-05-7C14H18ClN3S
Ethyl 4-chloro-5-methyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C16H20ClN3O2S, CAS 851879-24-8
Ethyl 4-chloro-5-methyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxylate
CAS 851879-24-8C16H20ClN3O2S
1-({4-Chloro-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl}methyl)-4-methylpiperidine chemical structure, C15H20ClN3S, CAS 793727-86-3
1-({4-Chloro-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl}methyl)-4-methylpiperidine
CAS 793727-86-3C15H20ClN3S
4-Methoxy-5-methyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C15H19N3O3S, CAS 877826-27-2
4-Methoxy-5-methyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 877826-27-2C15H19N3O3S
5,6-Dimethyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidin-4-amine chemical structure, C14H20N4S, CAS 878217-93-7
5,6-Dimethyl-2-(piperidin-1-ylmethyl)thieno[2,3-d]pyrimidin-4-amine
CAS 878217-93-7C14H20N4S