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Murcko scaffold

Ring system with 3 rings and 18 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
14
With full pages
8
Scaffold SMILES

O=S(=O)(c1ccc2[nH]cnc2c1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccc2[nH]cnc2c1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Morpholine, 4-[(1-ethyl-2-methyl-1H-benzimidazol-5-yl)sulfonyl]- chemical structure, C14H19N3O3S, CAS 185031-67-8
Morpholine, 4-[(1-ethyl-2-methyl-1H-benzimidazol-5-yl)sulfonyl]-
CAS 185031-67-8C14H19N3O3S
6-(Morpholine-4-sulfonyl)-1H-1,3-benzodiazol-1-ol chemical structure, C11H13N3O4S, CAS 730992-71-9
6-(Morpholine-4-sulfonyl)-1H-1,3-benzodiazol-1-ol
CAS 730992-71-9C11H13N3O4S
1-Butyl-2-methyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole chemical structure, C16H23N3O3S, CAS 736188-82-2
1-Butyl-2-methyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole
CAS 736188-82-2C16H23N3O3S
3-[5-(Morpholine-4-sulfonyl)-1-propyl-1H-1,3-benzodiazol-2-yl]propanoic acid chemical structure, C17H23N3O5S, CAS 731815-69-3
3-[5-(Morpholine-4-sulfonyl)-1-propyl-1H-1,3-benzodiazol-2-yl]propanoic acid
CAS 731815-69-3C17H23N3O5S
3-[1-Methyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]propanoic acid chemical structure, C15H19N3O5S, CAS 731820-90-9
3-[1-Methyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]propanoic acid
CAS 731820-90-9C15H19N3O5S
2-(Chloromethyl)-1-ethyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole chemical structure, C14H18ClN3O3S, CAS 785792-29-2
2-(Chloromethyl)-1-ethyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole
CAS 785792-29-2C14H18ClN3O3S
3-[1-Ethyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]propanoic acid chemical structure, C16H21N3O5S, CAS 790270-67-6
3-[1-Ethyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]propanoic acid
CAS 790270-67-6C16H21N3O5S
3-[1-Butyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]propanoic acid chemical structure, C18H25N3O5S, CAS 729575-86-4
3-[1-Butyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]propanoic acid
CAS 729575-86-4C18H25N3O5S
1-Butyl-2-(chloromethyl)-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole chemical structure, C16H22ClN3O3S, CAS 750599-31-6
1-Butyl-2-(chloromethyl)-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole
CAS 750599-31-6C16H22ClN3O3S
2-(Chloromethyl)-5-(4-morpholinylsulfonyl)-1-propyl-1H-benzimidazole chemical structure, C15H20ClN3O3S, CAS 851175-90-1
2-(Chloromethyl)-5-(4-morpholinylsulfonyl)-1-propyl-1H-benzimidazole
CAS 851175-90-1C15H20ClN3O3S
N-(1-Cyano-1,2-dimethylpropyl)-2-{[1-ethyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]sulfanyl}acetamide chemical structure, C21H29N5O4S2, CAS 1012138-36-1
N-(1-Cyano-1,2-dimethylpropyl)-2-{[1-ethyl-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-yl]sulfanyl}acetamide
CAS 1012138-36-1C21H29N5O4S2
2-Chloro-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole chemical structure, C11H12ClN3O3S, CAS 1359859-17-8
2-Chloro-5-(morpholine-4-sulfonyl)-1H-1,3-benzodiazole
CAS 1359859-17-8C11H12ClN3O3S
5-(Morpholine-4-sulfonyl)-1H-1,3-benzodiazole-2-sulfonic acid chemical structure, C11H13N3O6S2, CAS 1513877-24-1
5-(Morpholine-4-sulfonyl)-1H-1,3-benzodiazole-2-sulfonic acid
CAS 1513877-24-1C11H13N3O6S2
5-(Morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-amine chemical structure, C11H14N4O3S, CAS 2172600-50-7
5-(Morpholine-4-sulfonyl)-1H-1,3-benzodiazol-2-amine
CAS 2172600-50-7C11H14N4O3S