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Murcko scaffold

Ring system with 3 rings and 17 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
9
With full pages
8
Scaffold SMILES

O=C(c1ccccc1)c1cnc2[nH]ncc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cnc2[nH]ncc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(1,3-Dimethylpyrazolo[3,4-b]pyridin-5-yl)-(2-hydroxyphenyl)methanone chemical structure, C15H13N3O2, CAS 757193-25-2
(1,3-Dimethylpyrazolo[3,4-b]pyridin-5-yl)-(2-hydroxyphenyl)methanone
CAS 757193-25-2C15H13N3O2
(3,5-Dichloro-2-hydroxyphenyl)(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)methanone chemical structure, C14H9Cl2N3O2, CAS 736949-72-7
(3,5-Dichloro-2-hydroxyphenyl)(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)methanone
CAS 736949-72-7C14H9Cl2N3O2
4-Chloro-2-[1-(2-hydroxyethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl]phenol chemical structure, C16H14ClN3O3, CAS 793678-43-0
4-Chloro-2-[1-(2-hydroxyethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl]phenol
CAS 793678-43-0C16H14ClN3O3
(1,3-Dimethylpyrazolo[3,4-b]pyridin-5-yl)-(2-hydroxy-5-methylphenyl)methanone chemical structure, C16H15N3O2, CAS 851797-29-0
(1,3-Dimethylpyrazolo[3,4-b]pyridin-5-yl)-(2-hydroxy-5-methylphenyl)methanone
CAS 851797-29-0C16H15N3O2
(1,3-Dimethylpyrazolo[3,4-b]pyridin-5-yl)-(2-hydroxy-5-methoxyphenyl)methanone chemical structure, C16H15N3O3, CAS 851797-42-7
(1,3-Dimethylpyrazolo[3,4-b]pyridin-5-yl)-(2-hydroxy-5-methoxyphenyl)methanone
CAS 851797-42-7C16H15N3O3
2-{1,3-Dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl}-4-fluorophenol chemical structure, C15H12FN3O2, CAS 851797-46-1
2-{1,3-Dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl}-4-fluorophenol
CAS 851797-46-1C15H12FN3O2
(5-Fluoro-2-hydroxyphenyl)-[1-(2-hydroxyethyl)-3-methylpyrazolo[3,4-b]pyridin-5-yl]methanone chemical structure, C16H14FN3O3, CAS 851797-52-9
(5-Fluoro-2-hydroxyphenyl)-[1-(2-hydroxyethyl)-3-methylpyrazolo[3,4-b]pyridin-5-yl]methanone
CAS 851797-52-9C16H14FN3O3
Bms-265246 chemical structure, C18H17F2N3O2, CAS 582315-72-8
Bms-265246
CAS 582315-72-8C18H17F2N3O2
Methanone, (4-ethoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl- chemical structure, C15H13N3O2, CAS 57259-58-2
Methanone, (4-ethoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl-
CAS 57259-58-2C15H13N3O2