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Murcko scaffold

Ring system with 3 rings and 21 atoms

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
34
With full pages
19
Scaffold SMILES

O=C(NCc1ccccc1)c1conc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)c1conc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

N-(4-Fluorobenzyl)-5-methyl-3-phenyl-4-isoxazolecarboxamide chemical structure, C18H15FN2O2, CAS 313069-09-9
N-(4-Fluorobenzyl)-5-methyl-3-phenyl-4-isoxazolecarboxamide
CAS 313069-09-9C18H15FN2O2
N-(4-Chlorobenzyl)-5-methyl-3-phenyl-4-isoxazolecarboxamide chemical structure, C18H15ClN2O2, CAS 313069-16-8
N-(4-Chlorobenzyl)-5-methyl-3-phenyl-4-isoxazolecarboxamide
CAS 313069-16-8C18H15ClN2O2
N-Benzyl-5-methyl-3-phenyl-N-(propan-2-yl)-1,2-oxazole-4-carboxamide chemical structure, C21H22N2O2, CAS 710945-18-9
N-Benzyl-5-methyl-3-phenyl-N-(propan-2-yl)-1,2-oxazole-4-carboxamide
CAS 710945-18-9C21H22N2O2
N-Benzyl-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide chemical structure, C18H16N2O2, CAS 55153-40-7
N-Benzyl-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide
CAS 55153-40-7C18H16N2O2
N-Benzyl-3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H14ClFN2O2, CAS 153949-31-6
N-Benzyl-3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamide
CAS 153949-31-6C18H14ClFN2O2
3-(2-Chlorophenyl)-N-(3,4-dichlorobenzyl)-5-methyl-4-isoxazolecarboxamide chemical structure, C18H13Cl3N2O2, CAS 541519-08-8
3-(2-Chlorophenyl)-N-(3,4-dichlorobenzyl)-5-methyl-4-isoxazolecarboxamide
CAS 541519-08-8C18H13Cl3N2O2
3-(2-Chloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid 2-methoxy-benzylamide chemical structure, C19H17ClN2O3, CAS 331847-84-8
3-(2-Chloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid 2-methoxy-benzylamide
CAS 331847-84-8C19H17ClN2O3
N-Benzyl-3-(2,6-dichlorophenyl)-5-methyl-N-propan-2-yl-1,2-oxazole-4-carboxamide chemical structure, C21H20Cl2N2O2, CAS 349398-49-8
N-Benzyl-3-(2,6-dichlorophenyl)-5-methyl-N-propan-2-yl-1,2-oxazole-4-carboxamide
CAS 349398-49-8C21H20Cl2N2O2
N-Benzyl-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H14Cl2N2O2, CAS 153948-24-4
N-Benzyl-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide
CAS 153948-24-4C18H14Cl2N2O2
3-(2,6-Dichlorophenyl)-5-methyl-N-[(4-sulfamoylphenyl)methyl]-1,2-oxazole-4-carboxamide chemical structure, C18H15Cl2N3O4S, CAS 153948-25-5
3-(2,6-Dichlorophenyl)-5-methyl-N-[(4-sulfamoylphenyl)methyl]-1,2-oxazole-4-carboxamide
CAS 153948-25-5C18H15Cl2N3O4S
3-(2,6-Dichlorophenyl)-N-[(4-fluorophenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H13Cl2FN2O2, CAS 309950-08-1
3-(2,6-Dichlorophenyl)-N-[(4-fluorophenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide
CAS 309950-08-1C18H13Cl2FN2O2
N-[(4-Chlorophenyl)methyl]-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H13Cl3N2O2, CAS 353475-65-7
N-[(4-Chlorophenyl)methyl]-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide
CAS 353475-65-7C18H13Cl3N2O2
N-((3,4-Dichlorophenyl)methyl)-5-methyl-3-phenyl-4-isoxazolecarboxamide chemical structure, C18H14Cl2N2O2, CAS 329221-46-7
N-((3,4-Dichlorophenyl)methyl)-5-methyl-3-phenyl-4-isoxazolecarboxamide
CAS 329221-46-7C18H14Cl2N2O2
N-Benzyl-3-(2,6-dichlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide chemical structure, C19H16Cl2N2O2, CAS 349398-56-7
N-Benzyl-3-(2,6-dichlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
CAS 349398-56-7C19H16Cl2N2O2
N-Benzyl-3-(2-chlorophenyl)-N-ethyl-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C20H19ClN2O2, CAS 349130-80-9
N-Benzyl-3-(2-chlorophenyl)-N-ethyl-5-methyl-1,2-oxazole-4-carboxamide
CAS 349130-80-9C20H19ClN2O2
3-(2,6-Dichlorophenyl)-N-[(4-methoxyphenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C19H16Cl2N2O3, CAS 369395-49-3
3-(2,6-Dichlorophenyl)-N-[(4-methoxyphenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide
CAS 369395-49-3C19H16Cl2N2O3
N-Benzyl-3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H15ClN2O2, CAS 300377-64-4
N-Benzyl-3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide
CAS 300377-64-4C18H15ClN2O2
N-[(3-Chlorophenyl)methyl]-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide chemical structure, C18H15ClN2O2, CAS 749877-18-7
N-[(3-Chlorophenyl)methyl]-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide
CAS 749877-18-7C18H15ClN2O2
3-(2-Chlorophenyl)-N-[(4-fluorophenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H14ClFN2O2, CAS 401595-61-7
3-(2-Chlorophenyl)-N-[(4-fluorophenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide
CAS 401595-61-7C18H14ClFN2O2
3-(2-Chlorophenyl)-N-[(2-fluorophenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H14ClFN2O2, CAS 775298-94-7
3-(2-Chlorophenyl)-N-[(2-fluorophenyl)methyl]-5-methyl-1,2-oxazole-4-carboxamide
CAS 775298-94-7C18H14ClFN2O2
N-[(2-Methoxyphenyl)methyl]-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide chemical structure, C19H18N2O3, CAS 420844-79-7
N-[(2-Methoxyphenyl)methyl]-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide
CAS 420844-79-7C19H18N2O3
5-Methyl-3-phenyl-N-(1-phenylethyl)-4-isoxazolecarboxamide chemical structure, C19H18N2O2, CAS 313069-18-0
5-Methyl-3-phenyl-N-(1-phenylethyl)-4-isoxazolecarboxamide
CAS 313069-18-0C19H18N2O2
3-(2-Chloro-6-fluorophenyl)-5-methyl-N-[1-(4-methylphenyl)propyl]-1,2-oxazole-4-carboxamide chemical structure, C21H20ClFN2O2, CAS 524927-49-9
3-(2-Chloro-6-fluorophenyl)-5-methyl-N-[1-(4-methylphenyl)propyl]-1,2-oxazole-4-carboxamide
CAS 524927-49-9C21H20ClFN2O2
4-((3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxamido)methyl)benzoic acid chemical structure, C19H15ClN2O4, CAS 890959-61-2
4-((3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxamido)methyl)benzoic acid
CAS 890959-61-2C19H15ClN2O4