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Murcko scaffold

Ring system with 3 rings and 16 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
14
With full pages
4
Scaffold SMILES

c1ccc(-c2csc(-n3cccc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2csc(-n3cccc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1-[4-Acetyl-1-[4-(3,4-dimethylphenyl)-5-methyl-1,3-thiazol-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone chemical structure, C22H24N2O2S, CAS 701217-21-2
1-[4-Acetyl-1-[4-(3,4-dimethylphenyl)-5-methyl-1,3-thiazol-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone
CAS 701217-21-2C22H24N2O2S
1-[4-Acetyl-2,5-dimethyl-1-(5-methyl-4-phenyl-1,3-thiazol-2-yl)pyrrol-3-yl]ethanone chemical structure, C20H20N2O2S, CAS 461438-87-9
1-[4-Acetyl-2,5-dimethyl-1-(5-methyl-4-phenyl-1,3-thiazol-2-yl)pyrrol-3-yl]ethanone
CAS 461438-87-9C20H20N2O2S
1-[4-Acetyl-1-[4-(3,4-dimethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone chemical structure, C22H24N2O4S, CAS 700862-01-7
1-[4-Acetyl-1-[4-(3,4-dimethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone
CAS 700862-01-7C22H24N2O4S
1-[4-Acetyl-1-[4-(4-bromophenyl)-5-methyl-1,3-thiazol-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone chemical structure, C20H19BrN2O2S, CAS 700857-28-9
1-[4-Acetyl-1-[4-(4-bromophenyl)-5-methyl-1,3-thiazol-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone
CAS 700857-28-9C20H19BrN2O2S
Ethyl 4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylate chemical structure, C16H14N2O2S, CAS 439289-71-1
Ethyl 4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylate
CAS 439289-71-1C16H14N2O2S
Agn-PC-0loerh chemical structure, C24H30N2O2S, CAS 4977-39-3
Agn-PC-0loerh
CAS 4977-39-3C24H30N2O2S
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4-phenyl-1,3-thiazole chemical structure, C15H14N2S, CAS 95337-93-2
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4-phenyl-1,3-thiazole
CAS 95337-93-2C15H14N2S
4-Phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylic acid chemical structure, C14H10N2O2S, CAS 1239751-79-1
4-Phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylic acid
CAS 1239751-79-1C14H10N2O2S
4-(4-Methoxyphenyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylic acid chemical structure, C15H12N2O3S, CAS 1239727-73-1
4-(4-Methoxyphenyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxylic acid
CAS 1239727-73-1C15H12N2O3S
N-(3-Methoxypropyl)-4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide chemical structure, C18H19N3O2S, CAS 1282114-48-0
N-(3-Methoxypropyl)-4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide
CAS 1282114-48-0C18H19N3O2S
4-Phenyl-N-propyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide chemical structure, C17H17N3OS, CAS 1282140-60-6
4-Phenyl-N-propyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide
CAS 1282140-60-6C17H17N3OS
N-(2-Methoxyethyl)-4-(4-methoxyphenyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide chemical structure, C18H19N3O3S, CAS 1324067-73-3
N-(2-Methoxyethyl)-4-(4-methoxyphenyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide
CAS 1324067-73-3C18H19N3O3S
N-(2-Methoxyethyl)-4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide chemical structure, C17H17N3O2S, CAS 1324074-97-6
N-(2-Methoxyethyl)-4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide
CAS 1324074-97-6C17H17N3O2S
Methyl N-{[4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazol-5-yl]carbonyl}-beta-alaninate chemical structure, C18H17N3O3S, CAS 1401580-02-6
Methyl N-{[4-phenyl-2-(1H-pyrrol-1-yl)-1,3-thiazol-5-yl]carbonyl}-beta-alaninate
CAS 1401580-02-6C18H17N3O3S