CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
8
With full pages
5
Scaffold SMILES

C(=Cc1noc(-c2ccccc2)n1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1noc(-c2ccccc2)n1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Phenol, 2-[3-[2-[4-(dimethylamino)phenyl]ethenyl]-1,2,4-oxadiazol-5-yl]- chemical structure, C18H17N3O2, CAS 727675-48-1
Phenol, 2-[3-[2-[4-(dimethylamino)phenyl]ethenyl]-1,2,4-oxadiazol-5-yl]-
CAS 727675-48-1C18H17N3O2
2-(3-{(E)-2-[4-(Methylsulfanyl)phenyl]ethenyl}-1,2,4-oxadiazol-5-yl)phenyl acetate chemical structure, C19H16N2O3S, CAS 901886-24-6
2-(3-{(E)-2-[4-(Methylsulfanyl)phenyl]ethenyl}-1,2,4-oxadiazol-5-yl)phenyl acetate
CAS 901886-24-6C19H16N2O3S
[2-[3-[(E)-2-(4-Methoxyphenyl)ethenyl]-1,2,4-oxadiazol-5-yl]phenyl] acetate chemical structure, C19H16N2O4, CAS 901886-16-6
[2-[3-[(E)-2-(4-Methoxyphenyl)ethenyl]-1,2,4-oxadiazol-5-yl]phenyl] acetate
CAS 901886-16-6C19H16N2O4
(E)-2-(3-(3,4-Dimethoxystyryl)-1,2,4-oxadiazol-5-yl)phenol chemical structure, C18H16N2O4, CAS 831234-83-4
(E)-2-(3-(3,4-Dimethoxystyryl)-1,2,4-oxadiazol-5-yl)phenol
CAS 831234-83-4C18H16N2O4
N-[4-[(E)-2-[(5Z)-5-(6-Oxocyclohexa-2,4-dien-1-ylidene)-2H-1,2,4-oxadiazol-3-yl]ethenyl]phenyl]acetamide chemical structure, C18H15N3O3, CAS 831200-48-7
N-[4-[(E)-2-[(5Z)-5-(6-Oxocyclohexa-2,4-dien-1-ylidene)-2H-1,2,4-oxadiazol-3-yl]ethenyl]phenyl]acetamide
CAS 831200-48-7C18H15N3O3
2-{2-[5-(2-Hydroxyphenyl)-1,2,4-oxadiazol-3-yl]vinyl}phenol chemical structure, C16H12N2O3, CAS 342385-04-0
2-{2-[5-(2-Hydroxyphenyl)-1,2,4-oxadiazol-3-yl]vinyl}phenol
CAS 342385-04-0C16H12N2O3
(6Z)-6-[3-[(E)-2-Phenylethenyl]-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,4-dien-1-one chemical structure, C16H12N2O2, CAS 144726-75-0
(6Z)-6-[3-[(E)-2-Phenylethenyl]-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,4-dien-1-one
CAS 144726-75-0C16H12N2O2
2-(3-{(E)-2-[4-(Methylsulfanyl)phenyl]ethenyl}-1,2,4-oxadiazol-5-yl)phenol chemical structure, C17H14N2O2S, CAS 831199-68-9
2-(3-{(E)-2-[4-(Methylsulfanyl)phenyl]ethenyl}-1,2,4-oxadiazol-5-yl)phenol
CAS 831199-68-9C17H14N2O2S