CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
6
With full pages
0
Scaffold SMILES

c1ccc(C2CCCC(c3ccccc3)O2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2CCCC(c3ccccc3)O2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

1,5-Bis(3,4-dimethoxyphenyl)tetrahydropyran chemical structure, C21H26O5, CAS 143317-76-4
1,5-Bis(3,4-dimethoxyphenyl)tetrahydropyran
CAS 143317-76-4C21H26O5
1,5-Anhydro-2,4-dideoxy-2-methyl-3-C-methyl-1,5-diphenylpentitol chemical structure, C19H22O2, CAS 7229-43-8
1,5-Anhydro-2,4-dideoxy-2-methyl-3-C-methyl-1,5-diphenylpentitol
CAS 7229-43-8C19H22O2
(2,6-Diphenyloxan-2-yl)phosphonic acid chemical structure, C17H19O4P, CAS 62173-57-3
(2,6-Diphenyloxan-2-yl)phosphonic acid
CAS 62173-57-3C17H19O4P
Methyl 3-(4-acetoxy-tetrahydro-6-phenyl-2H-pyran-2-yl)benzoate chemical structure, C21H22O5, CAS 1918178-09-2
Methyl 3-(4-acetoxy-tetrahydro-6-phenyl-2H-pyran-2-yl)benzoate
CAS 1918178-09-2C21H22O5
Ezetimibe impurity 45 chemical structure, C18H17FO4, CAS 1618657-31-0
Ezetimibe impurity 45
CAS 1618657-31-0C18H17FO4
4-((2R,3S,6S)-6-(4-Fluorophenyl)-3-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenol(Ezetimibe Impurity) chemical structure, C18H19FO3, CAS 2742940-92-5
4-((2R,3S,6S)-6-(4-Fluorophenyl)-3-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenol(Ezetimibe Impurity)
CAS 2742940-92-5C18H19FO3