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Murcko scaffold

2-(4-Benzylpiperazino)-1-phenyl-1-ethanone scaffold

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
11
With full pages
3
Scaffold SMILES

O=C(CN1CCN(Cc2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(4-Benzylpiperazino)-1-phenyl-1-ethanone page
Murcko scaffold O=C(CN1CCN(Cc2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Acetophenone, 2-(4-(p-tert-butylbenzyl)piperazinyl)-3',4',5'-trimethoxy-, dihydrochloride chemical structure, C26H38Cl2N2O4, CAS 16785-31-2
Acetophenone, 2-(4-(p-tert-butylbenzyl)piperazinyl)-3',4',5'-trimethoxy-, dihydrochloride
CAS 16785-31-2C26H38Cl2N2O4
Acetophenone, 2-(4-(m-methylbenzyl)piperazinyl)-3',4',5'-trimethoxy-, dihydrochloride chemical structure, C23H32Cl2N2O4, CAS 17755-60-1
Acetophenone, 2-(4-(m-methylbenzyl)piperazinyl)-3',4',5'-trimethoxy-, dihydrochloride
CAS 17755-60-1C23H32Cl2N2O4
Acetophenone, 1-(4-benzylpiperazinyl)-3',4',5'-trimethoxy-, dihydrochloride chemical structure, C22H30Cl2N2O4, CAS 17837-65-9
Acetophenone, 1-(4-benzylpiperazinyl)-3',4',5'-trimethoxy-, dihydrochloride
CAS 17837-65-9C22H30Cl2N2O4
2-(4-Benzylpiperazino)-1-phenyl-1-ethanone chemical structure, C19H22N2O, CAS 41298-80-0
2-(4-Benzylpiperazino)-1-phenyl-1-ethanone
CAS 41298-80-0C19H22N2O
2-[4-(Phenylmethyl)-1-piperazinyl]-1-(2,4,6-trinitrophenyl)ethanone chemical structure, C19H19N5O7, CAS 669716-59-0
2-[4-(Phenylmethyl)-1-piperazinyl]-1-(2,4,6-trinitrophenyl)ethanone
CAS 669716-59-0C19H19N5O7
2-(4-Benzylpiperazin-1-yl)-1-(2,4-dihydroxy-3-methylphenyl)ethanone chemical structure, C20H24N2O3, CAS 869340-92-1
2-(4-Benzylpiperazin-1-yl)-1-(2,4-dihydroxy-3-methylphenyl)ethanone
CAS 869340-92-1C20H24N2O3
2-(4-Benzyl-1-piperazinyl)-1-(4-methylphenyl)ethanone dihydrochloride chemical structure, C20H26Cl2N2O, CAS 882865-18-1
2-(4-Benzyl-1-piperazinyl)-1-(4-methylphenyl)ethanone dihydrochloride
CAS 882865-18-1C20H26Cl2N2O
2-(4-Benzyl-1-piperazinyl)-1-phenylethanone dihydrochloride chemical structure, C19H24Cl2N2O, CAS 41379-37-7
2-(4-Benzyl-1-piperazinyl)-1-phenylethanone dihydrochloride
CAS 41379-37-7C19H24Cl2N2O
1-(3,4-Dimethoxyphenyl)-2-[4-(1-phenylethyl)piperazin-1-yl]ethan-1-one chemical structure, C22H28N2O3, CAS 918480-88-3
1-(3,4-Dimethoxyphenyl)-2-[4-(1-phenylethyl)piperazin-1-yl]ethan-1-one
CAS 918480-88-3C22H28N2O3
2-(4-Benzylpiperazin-1-yl)-1-phenylethan-1-one hydrobromide chemical structure, C19H23BrN2O, CAS 1173022-87-1
2-(4-Benzylpiperazin-1-yl)-1-phenylethan-1-one hydrobromide
CAS 1173022-87-1C19H23BrN2O
2-[4-(3,4-Dichloro-benzyl)-piperazin-1-yl]-1-phenyl-ethanone chemical structure, C19H20Cl2N2O, CAS 1385696-17-2
2-[4-(3,4-Dichloro-benzyl)-piperazin-1-yl]-1-phenyl-ethanone
CAS 1385696-17-2C19H20Cl2N2O