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Murcko scaffold

5-(1H-Pyrazol-4-yl)pyrrolidin-2-one scaffold

111 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 111
With full pages: 7

Scaffold SMILES

O=C1CCC(c2cn[nH]c2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5-(1H-Pyrazol-4-yl)pyrrolidin-2-one page

Murcko scaffold O=C1CCC(c2cn[nH]c2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 111 chemicals

1-tert-Butyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C13H19N3O3, CAS 1479954-34-1

1-tert-Butyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid

CAS 1479954-34-1C₁₃H₁₉N₃O₃

1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C10H13N3O3, CAS 1339159-33-9

1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid

CAS 1339159-33-9C₁₀H₁₃N₃O₃

4-Amino-1-methyl-5-(trimethyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C11H18N4O, CAS 1342969-82-7

4-Amino-1-methyl-5-(trimethyl-1H-pyrazol-4-yl)pyrrolidin-2-one

CAS 1342969-82-7C₁₁H₁₈N₄O

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1522082-11-6

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid

CAS 1522082-11-6C₁₁H₁₅N₃O₃

rac-(4R,5S)-4-Amino-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methylpyrrolidin-2-one chemical structure, C10H16N4O, CAS 1807914-35-7

rac-(4R,5S)-4-Amino-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methylpyrrolidin-2-one

CAS 1807914-35-7C₁₀H₁₆N₄O

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1513312-17-8

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid

CAS 1513312-17-8C₁₂H₁₇N₃O₃

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C13H19N3O4, CAS 1501778-35-3

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxylic acid

CAS 1501778-35-3C₁₃H₁₉N₃O₄

(4S,5R)-4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C10H16N4O, CAS 1807940-01-7

(4S,5R)-4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one

CAS 1807940-01-7C₁₀H₁₆N₄O

(4S,5R)-4-(Aminomethyl)-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)pyrrolidin-2-one chemical structure, C13H22N4O2, CAS 1807941-81-6

(4S,5R)-4-(Aminomethyl)-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)pyrrolidin-2-one

CAS 1807941-81-6C₁₃H₂₂N₄O₂

(4R,5S)-4-Amino-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methylpyrrolidin-2-one chemical structure, C10H16N4O, CAS 1820574-32-0

(4R,5S)-4-Amino-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methylpyrrolidin-2-one

CAS 1820574-32-0C₁₀H₁₆N₄O

(4R,5S)-4-Amino-1-methyl-5-(trimethyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C11H18N4O, CAS 1820583-26-3

(4R,5S)-4-Amino-1-methyl-5-(trimethyl-1H-pyrazol-4-yl)pyrrolidin-2-one

CAS 1820583-26-3C₁₁H₁₈N₄O

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxamide chemical structure, C11H16N4O2, CAS 1955560-56-1

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxamide

CAS 1955560-56-1C₁₁H₁₆N₄O₂

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C13H20N4O3, CAS 1955498-05-1

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxamide

CAS 1955498-05-1C₁₃H₂₀N₄O₃

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carbonitrile chemical structure, C13H18N4O2, CAS 1795355-09-7

2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carbonitrile

CAS 1795355-09-7C₁₃H₁₈N₄O₂

1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C10H14N4O2, CAS 1803570-84-4

1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxamide

CAS 1803570-84-4C₁₀H₁₄N₄O₂

(4S,5R)-4-(Aminomethyl)-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methylpyrrolidin-2-one chemical structure, C11H18N4O, CAS 1808324-17-5

(4S,5R)-4-(Aminomethyl)-5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methylpyrrolidin-2-one

CAS 1808324-17-5C₁₁H₁₈N₄O

(4S,5R)-4-(Aminomethyl)-1-methyl-5-(trimethyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C12H20N4O, CAS 1807916-68-2

(4S,5R)-4-(Aminomethyl)-1-methyl-5-(trimethyl-1H-pyrazol-4-yl)pyrrolidin-2-one

CAS 1807916-68-2C₁₂H₂₀N₄O

(4S,5R)-4-(Aminomethyl)-1-(2-methoxyethyl)-5-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C12H20N4O2, CAS 1808338-42-2

(4S,5R)-4-(Aminomethyl)-1-(2-methoxyethyl)-5-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one

CAS 1808338-42-2C₁₂H₂₀N₄O₂

(2R,3R)-2-(1,5-Dimethylpyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxamide chemical structure, C11H16N4O2, CAS 1820569-81-0

(2R,3R)-2-(1,5-Dimethylpyrazol-4-yl)-1-methyl-5-oxopyrrolidine-3-carboxamide

CAS 1820569-81-0C₁₁H₁₆N₄O₂

1-tert-Butyl-2-[1-(2-methoxyethyl)-1H-pyrazol-4-yl]-5-oxopyrrolidine-3-carboxylic acid chemical structure, C15H23N3O4, CAS 1795305-12-2

1-tert-Butyl-2-[1-(2-methoxyethyl)-1H-pyrazol-4-yl]-5-oxopyrrolidine-3-carboxylic acid

CAS 1795305-12-2C₁₅H₂₃N₃O₄

(2R,3R)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carbonitrile chemical structure, C13H18N4O2, CAS 1820575-71-0

(2R,3R)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carbonitrile

CAS 1820575-71-0C₁₃H₁₈N₄O₂

(4S,5R)-4-(Aminomethyl)-1-tert-butyl-5-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C13H22N4O, CAS 1820569-75-2

(4S,5R)-4-(Aminomethyl)-1-tert-butyl-5-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one

CAS 1820569-75-2C₁₃H₂₂N₄O

(2R,3R)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C13H20N4O3, CAS 1820569-64-9

(2R,3R)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxamide

CAS 1820569-64-9C₁₃H₂₀N₄O₃

(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C10H14N4O2, CAS 1820569-87-6

(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxamide

CAS 1820569-87-6C₁₀H₁₄N₄O₂