Murcko scaffold
2-Hydroxy-5-phenylpyridine scaffold
776 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 776
- With full pages
- 32
Scaffold SMILES
O=c1ccc(-c2ccccc2)c[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1](/scaffold/RWFAQYWIBBVEBY-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 241 to 288 of 776 chemicals
5-(3-Formylphenyl)-2-hydroxyisonicotinic acid
CAS 1261945-51-0C13H9NO4
5-(4-Formylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 1261945-76-9C13H9NO4
5-(4-Formylphenyl)-2-hydroxyisonicotinic acid
CAS 1261905-71-8C13H9NO4
5-(2,3-Dimethylphenyl)-2-hydroxynicotinic acid
CAS 1261953-82-5C14H13NO3
5-(2,3-Dimethylphenyl)-2-hydroxyisonicotinic acid
CAS 1261925-92-1C14H13NO3
5-(2,5-Dimethylphenyl)-2-hydroxynicotinic acid
CAS 1261889-73-9C14H13NO3
5-(2,5-Dimethylphenyl)-2-hydroxyisonicotinic acid
CAS 1261973-29-8C14H13NO3
5-(4-Ethylphenyl)-2-hydroxynicotinic acid
CAS 1261973-49-2C14H13NO3
5-(4-Ethylphenyl)-2-hydroxyisonicotinic acid
CAS 1261953-86-9C14H13NO3
5-(2,4-Dimethylphenyl)-2-hydroxynicotinic acid
CAS 1261973-57-2C14H13NO3
5-(2,4-Dimethylphenyl)-2-hydroxyisonicotinic acid
CAS 1261967-49-0C14H13NO3
5-(3,5-Dimethylphenyl)-2-hydroxynicotinic acid
CAS 1261953-92-7C14H13NO3
5-(3,5-Dimethylphenyl)-2-hydroxyisonicotinic acid
CAS 1261988-87-7C14H13NO3
2-Hydroxy-5-(2-hydroxymethylphenyl)nicotinic acid
CAS 1261903-97-2C13H11NO4
2-Hydroxy-5-(2-hydroxymethylphenyl)isonicotinic acid
CAS 1261945-99-6C13H11NO4
2-Hydroxy-5-(3-hydroxymethylphenyl)nicotinic acid
CAS 1261930-07-7C13H11NO4
2-Hydroxy-5-(3-hydroxymethylphenyl)isonicotinic acid
CAS 1261991-87-0C13H11NO4
2-Hydroxy-5-(4-hydroxymethylphenyl)nicotinic acid
CAS 1261929-86-5C13H11NO4
2-Hydroxy-5-(4-hydroxymethylphenyl)isonicotinic acid
CAS 1261904-01-1C13H11NO4
2-Hydroxy-5-(2-methoxyphenyl)nicotinic acid
CAS 1261997-05-0C13H11NO4
2-Hydroxy-5-(2-methoxyphenyl)isonicotinic acid
CAS 1261962-20-2C13H11NO4
2-Hydroxy-5-(3-methoxyphenyl)isonicotinic acid
CAS 1261954-00-0C13H11NO4
2-Hydroxy-5-(4-methoxyphenyl)isonicotinic acid
CAS 1261954-03-3C13H11NO4
5-(2-Fluoro-4-methylphenyl)-2-hydroxynicotinic acid
CAS 1261989-12-1C13H10FNO3
- 5-(2-Fluoro-4-methylphenyl)-2-hydroxyisonicotinic acid1261975-30-7C13H10FNO3
- 5-(2-Fluoro-5-methylphenyl)-2-hydroxynicotinic acid1261997-19-6C13H10FNO3
- 5-(2-Fluoro-5-methylphenyl)-2-hydroxyisonicotinic acid1261997-29-8C13H10FNO3
- 5-(3-Fluoro-2-methylphenyl)-2-hydroxynicotinic acid1261997-54-9C13H10FNO3
- 5-(3-Fluoro-2-methylphenyl)-2-hydroxyisonicotinic acid1261930-10-2C13H10FNO3
- 5-(3-Fluoro-4-methylphenyl)-2-hydroxynicotinic acid1261954-09-9C13H10FNO3
- 5-(3-Fluoro-4-methylphenyl)-2-hydroxyisonicotinic acid1261904-73-7C13H10FNO3
- 5-(4-Fluoro-3-methylphenyl)-2-hydroxynicotinic acid1261930-54-4C13H10FNO3
- 5-(4-Fluoro-3-methylphenyl)-2-hydroxyisonicotinic acid1261954-16-8C13H10FNO3
- 5-(5-Fluoro-2-methylphenyl)-2-hydroxynicotinic acid1261992-18-0C13H10FNO3
- 5-(5-Fluoro-2-methylphenyl)-2-hydroxyisonicotinic acid1261946-64-8C13H10FNO3
- 5-(3-Fluoro-4-hydroxyphenyl)-2-hydroxynicotinic acid1261954-26-0C12H8FNO4
- 5-(3-Fluoro-4-hydroxyphenyl)-2-hydroxyisonicotinic acid1261904-11-3C12H8FNO4
- 5-(3-Fluoro-5-hydroxyphenyl)-2-hydroxynicotinic acid1261954-41-9C12H8FNO4
- 5-(3-Fluoro-5-hydroxyphenyl)-2-hydroxyisonicotinic acid1261954-46-4C12H8FNO4
- 5-(4-Fluoro-2-hydroxyphenyl)-2-hydroxynicotinic acid1261889-91-1C12H8FNO4
- 5-(4-Fluoro-2-hydroxyphenyl)-2-hydroxyisonicotinic acid1261954-34-0C12H8FNO4
- 5-(5-Fluoro-2-hydroxyphenyl)-2-hydroxynicotinic acid1261962-95-1C12H8FNO4
- 5-(5-Fluoro-2-hydroxyphenyl)-2-hydroxyisonicotinic acid1261931-11-6C12H8FNO4
- 5-(2-Chlorophenyl)-2-hydroxyisonicotinic acid1261990-10-6C12H8ClNO3
- 5-(3-Chlorophenyl)-2-hydroxyisonicotinic acid1261963-00-1C12H8ClNO3
- 5-(4-Chlorophenyl)-2-hydroxyisonicotinic acid1261954-43-1C12H8ClNO3
- 5-(2,4-Difluorophenyl)-2-hydroxynicotinic acid1261950-82-6C12H7F2NO3
- 5-(2,4-Difluorophenyl)-2-hydroxyisonicotinic acid1261963-07-8C12H7F2NO3
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(-c2ccccc2)cc11,627 chemicals
c1ccc(N2CCNCC2)cc1595 chemicals
c1ccc(C2CCNCC2)cc1277 chemicals
c1ccc(C2CCCCC2)cc1274 chemicals
c1ccc(N2CCCCC2)cc1235 chemicals
c1ccc(-c2ccccn2)cc1219 chemicals
c1ccc(N2CCOCC2)cc1202 chemicals
C1=CC(c2ccccc2)C=CN1155 chemicals
c1ccc(-c2ccncc2)cc1124 chemicals
c1ccc(-c2ccccn2)nc1118 chemicals
c1ccc(N2CCNCC2)nc1112 chemicals
c1ccc(-c2ncccn2)cc1107 chemicals