Murcko scaffold
Ring system with 3 rings and 16 atoms
109 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 16
- Chemicals
- 109
- With full pages
- 14
Scaffold SMILES
C1=Cc2ccccc2C1=Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 109 chemicals
5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
CAS 32004-68-5C20H17FO3S
1-(4-N-Methyl-N-nitrosaminobenzylidene)indene
C17H14N2O
![5-Fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid chemical structure, C20H17FO2S, CAS 32004-67-4](/s/LFWHFZJPXXOYNR-UHFFFAOYSA-N.svg)
5-Fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
CAS 32004-67-4C20H17FO2S
![2-[6-Fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]acetic acid chemical structure, C20H17FO4S, CAS 59864-04-9](/s/MVGSNCBCUWPVDA-UHFFFAOYSA-N.svg)
2-[6-Fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]acetic acid
CAS 59864-04-9C20H17FO4S
![1-[(2,4,5-Trimethoxyphenyl)methylidene]indene chemical structure, C19H18O3](/s/RJQDQZJSACRDTL-UHFFFAOYSA-N.svg)
1-[(2,4,5-Trimethoxyphenyl)methylidene]indene
C19H18O3
![4-[(1H-Inden-1-ylidene)methyl]-N,N,2-trimethylaniline chemical structure, C19H19N, CAS 4906-89-2](/s/APDWNFSVJPHAHU-UHFFFAOYSA-N.svg)
4-[(1H-Inden-1-ylidene)methyl]-N,N,2-trimethylaniline
CAS 4906-89-2C19H19N
4-(Inden-1-ylidenemethyl)-2-methoxy-N-methylaniline
CAS 2448-83-1C18H17NO
Benzenamine,n-ethyl-4-(1H-inden-1-ylidenemethyl)-N-nitroso-
CAS 16699-37-9C18H16N2O
2-Chloro-4-(inden-1-ylidenemethyl)-N-methylaniline
CAS 28164-40-1C17H14ClN
![1-[(4-Propan-2-ylphenyl)methylidene]indene chemical structure, C19H18](/s/DMAOTKUXIGUJMG-UHFFFAOYSA-N.svg)
1-[(4-Propan-2-ylphenyl)methylidene]indene
C19H18
1H-Indene, 3-(1,1-dimethylethyl)-1-(2,2-dimethyl-1-phenylpropylidene)-
CAS 61578-68-5C24H28
trans-Sulindac
CAS 53933-60-1C20H17FO3S
Sulindac
CAS 38194-50-2C20H17FO3S
![(1E)-1-[(4-Bromophenyl)methylene]indene chemical structure, C16H11Br, CAS 30251-62-8](/s/IKSNXMHAGMXMCA-SDNWHVSQSA-N.svg)
(1E)-1-[(4-Bromophenyl)methylene]indene
CAS 30251-62-8C16H11Br
Dabi
CAS 443-30-1C18H17N
Sulindac sulfide
CAS 49627-27-2C20H17FO2S
1H-Indene, 1-(phenylmethylene)-
CAS 5394-86-5C16H12
![(1E)-1-[(2-Methoxyphenyl)methylene]indene chemical structure, C17H14O, CAS 2428-40-2](/s/OBWYFXPPDTYSBV-WYMLVPIESA-N.svg)
(1E)-1-[(2-Methoxyphenyl)methylene]indene
CAS 2428-40-2C17H14O
Sulindac methyl ester
CAS 134439-52-4C21H19FO3S
Aniline, 4-(5,6-dimethoxyindenylidene)methyl-N,N-dimethyl-
CAS 21899-30-9C20H21NO2
2,6-Dibromo-4-(1H-inden-1-ylidenemethyl)-N-methylaniline
CAS 26389-98-0C17H13Br2N
![(1E)-1-[(4-Methylsulfanylphenyl)methylene]indene chemical structure, C17H14S, CAS 30117-67-0](/s/BLDWJYPPZFJELO-NTCAYCPXSA-N.svg)
(1E)-1-[(4-Methylsulfanylphenyl)methylene]indene
CAS 30117-67-0C17H14S
2,6-Dibromo-4-(1H-inden-1-ylidenemethyl)aniline
CAS 28164-46-7C16H11Br2N
Sulindac sulfone
CAS 59973-80-7C20H17FO4S
- 1-(4-Aminobenzylidene)indene487-61-6C16H13N
- 1-(4-(1H-Inden-1-ylidenemethyl)phenyl)-3,3-dimethyl-1-triazene30117-77-2C18H17N3
- N-[4-[(E)-Inden-1-ylidenemethyl]phenyl]acetamide2428-32-2C18H15NO
- 2-Bromo-4-(1H-inden-1-ylidenemethyl)-N,N-dimethylaniline28164-39-8C18H16BrN
- 4-[(E)-Inden-1-ylidenemethyl]-2,5-dimethoxy-N,N-dimethyl-aniline2428-39-9C20H21NO2
- 1-(2,5-Dimethoxybenzylidene)-1H-indene2428-42-4C18H16O2
- 4-[(Z)-(3-Bromoinden-1-ylidene)methyl]-N,N-dimethylaniline28164-47-8C18H16BrN
- Guanidine, (4-(1H-inden-1-ylidenemethyl)phenyl)-30117-70-5C17H15N3
- N,N-Diethyl-4-(1H-inden-1-ylidenemethyl)aniline2428-35-5C20H21N
- 2-Fluoro-4-(1H-inden-1-ylidenemethyl)-N,N-dimethylaniline28220-39-5C18H16FN
- 4-(1H-Inden-1-ylidenemethyl)-2-iodo-N-methylaniline28164-42-3C17H14IN
- 2,6-Dichloro-4-(1H-inden-1-ylidenemethyl)-N-methylaniline28164-43-4C17H13Cl2N
- p-Toluidine, 2,6-dichloro-alpha-inden-1-ylidene-28164-45-6C16H11Cl2N
- 1-(2,4,5-Trimethoxybenzylidene)-1H-indene2448-79-5C19H18O3
- N-[2-Chloro-4-(1H-inden-1-ylidenemethyl)phenyl]-N,N-dimethylamine26389-97-9C18H16ClN
- N-Ethyl-4-[(E)-inden-1-ylidenemethyl]aniline2428-34-4C18H17N
- p-Toluidine, alpha-inden-1-ylidene-N-methyl-N-nitroso-16699-07-3C17H14N2O
- 5-Fluoro-2-methyl-1-(p-methylthiobenzylidene)-3-indenyl acetic acid61812-45-1C20H17FO2S
- N,N-Dibutyl-4-(1H-inden-1-ylidenemethyl)aniline2448-82-0C24H29N
- 4-(1H-Inden-1-ylidenemethyl)phenyl methyl ether2428-41-3C17H14O
- (1E)-1-[(4-Isopropylphenyl)methylene]indene30251-61-7C19H18
- (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid1316775-50-4C20H17FO4S
- N,N-Bis(2-chloroethyl)-4-[(Z)-inden-1-ylidenemethyl]aniline2448-77-3C20H19Cl2N
- N-[3-Chloro-4-(1H-inden-1-ylidenemethyl)phenyl]-N,N-dimethylamine28220-40-8C18H16ClN
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cnc3ccccc32)cc1168 chemicals![Scaffold O=c1[nH]c(=O)c2c(ncn2Cc2ccccc2)[nH]1](/scaffold/XDUTVTQACWYOMX-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(ncn2Cc2ccccc2)[nH]1167 chemicals
c1ccc(Cn2ccc3ccccc32)cc1100 chemicals
O=S(=O)(c1ccccc1)n1cnc2ccccc2168 chemicals
O=C(c1ccccc1)c1coc2ccccc1255 chemicals
O=S(=O)(c1ccccc1)n1ccc2ccccc2143 chemicals
O=c1oc2ccccc2n1Cc1ccccc138 chemicals
O=S(=O)(c1ccccc1)N1CCc2ccccc2133 chemicals
O=C(c1ccccc1)N1CCc2ccccc2133 chemicals
O=C(c1ccccc1)n1ccc2ccccc2131 chemicals
c1ccc(Cn2cnc3cncnc32)cc130 chemicals
O=C(c1ccccc1)c1ccc2ccccn1229 chemicals