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Murcko scaffold

Ring system with 3 rings and 22 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
4
With full pages
1
Scaffold SMILES

O=C1NN(c2ccccc2)C(=O)C1=CC=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NN(c2ccccc2)C(=O)C1=CC=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

4-[3-(2-Chlorophenyl)prop-2-enylidene]-1-phenylpyrazolidine-3,5-dione chemical structure, C18H13ClN2O2
4-[3-(2-Chlorophenyl)prop-2-enylidene]-1-phenylpyrazolidine-3,5-dione
C18H13ClN2O2
1-(3,4-Dimethylphenyl)-4-(3-{3-nitrophenyl}-2-propenylidene)-3,5-pyrazolidinedione chemical structure, C20H17N3O4, CAS 330967-26-5
1-(3,4-Dimethylphenyl)-4-(3-{3-nitrophenyl}-2-propenylidene)-3,5-pyrazolidinedione
CAS 330967-26-5C20H17N3O4
Cpypp chemical structure, C18H13ClN2O2, CAS 310460-39-0
Cpypp
CAS 310460-39-0C18H13ClN2O2
(4Z)-4-[(E)-3-(2-Chlorophenyl)prop-2-enylidene]-1-phenylpyrazolidine-3,5-dione chemical structure, C18H13ClN2O2
(4Z)-4-[(E)-3-(2-Chlorophenyl)prop-2-enylidene]-1-phenylpyrazolidine-3,5-dione
C18H13ClN2O2